Interactor 1: NOTC1 (P46531)
Neurogenic locus notch homolog protein 1 (Notch 1) (hN1) (Translocation-associated notch protein TAN-1) [Cleaved into: Notch 1 extracellular truncation (NEXT); Notch 1 intracellular domain (NICD)]
Gene: NOTCH1

Interactor 2: HIF1N (Q9NWT6)
Hypoxia-inducible factor 1-alpha inhibitor (EC 1.14.11.30) (EC 1.14.11.n4) (Factor inhibiting HIF-1) (FIH-1) (Hypoxia-inducible factor asparagine hydroxylase)
Gene: HIF1AN

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.41 1.00 0.647

The method score is based on:

Property Details
Experiments unassigned1260
Identification Methods hydroxylase assay
Interaction Type hydroxylation reaction

The annotation score is based on:

Property Details
Interacting Pfam domains Ank~Cupin_8
Common GO terms GO:0005112 - Notch binding
GO:0005654 - nucleoplasm
GO:0005829 - cytosol
Homologous interactions 14

Homologous interactions

Color coding for hit scores

1 2555
Hs

1 349
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Last updated: 15 Jul 2024