HitPredict

Interactor 1: YAP1 (P46937)
Transcriptional coactivator YAP1 (Yes-associated protein 1) (Protein yorkie homolog) (Yes-associated protein YAP65 homolog)
Gene: YAP1

Interactor 2: EREP3 (P81408)
Protein ENTREP3 (Endosomal transmembrane epsin interactor 3) (Protein COTE1)
Gene: ENTREP3

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.58	0.60	0.595

Property	Details
Experiments	26186194, 35044719
Identification Methods	affinity chromatography technology, unspecified method, phage display
Interaction Type	physical association, direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0016020 - membrane
Homologous interactions	17

Homologous interactions

Color coding for hit scores

	1 504 Hs			1 668
+	Hs
		946429 ITCH_HUMAN (3-504): 3.59e-121: 378: 15.17		EREP3_HUMAN (1-668): 0: 1058: 100.00
+	Hs
		946430 NED4L_HUMAN (4-504): 4.82e-115: 364: 19.73		EREP3_HUMAN (1-668): 0: 1058: 100.00
+	Hs
		946437 WWP1_HUMAN (4-504): 1.27e-114: 361: 14.42		EREP3_HUMAN (1-668): 0: 1058: 100.00
+	Hs
		808086 NEDD4_HUMAN (40-504): 2.15e-103: 338: 19.26		EREP3_HUMAN (1-668): 0: 1058: 100.00
+	Hs
		946447 WWOX_HUMAN (166-263): 7.4e-29: 120: 30.61		EREP3_HUMAN (1-668): 0: 1058: 100.00
+	Hs
		946405 HECW1_HUMAN (2-222): 1.33e-24: 110: 14.96		EREP3_HUMAN (1-668): 0: 1058: 100.00
+	Hs
		946449 HECW2_HUMAN (13-303): 1.56e-14: 79: 14.79		EREP3_HUMAN (1-668): 0: 1058: 100.00
+	Hs
		125488 WWP2_HUMAN (12-504): 8.56e-129: 397: 16.54		EREP1_HUMAN (111-367): 3.33e-88: 284: 23.91
+	Hs
		1079771 ITCH_HUMAN (3-504): 3.59e-121: 378: 15.17		EREP1_HUMAN (111-367): 3.33e-88: 284: 23.91
+	Hs
		1079773 NED4L_HUMAN (4-504): 4.82e-115: 364: 19.73		EREP1_HUMAN (111-367): 3.33e-88: 284: 23.91
+	Hs
		1079783 WWP1_HUMAN (4-504): 1.27e-114: 361: 14.42		EREP1_HUMAN (111-367): 3.33e-88: 284: 23.91
+	Hs
		808136 NEDD4_HUMAN (40-504): 2.15e-103: 338: 19.26		EREP1_HUMAN (111-367): 3.33e-88: 284: 23.91
+	Hs
		125597 WWP2_HUMAN (12-504): 8.56e-129: 397: 16.54		Q8WU02_HUMAN (267-419): 3.85e-48: 168: 23.08
+	Hs
		1259694 WWP1_HUMAN (4-504): 1.27e-114: 361: 14.42		Q8WU02_HUMAN (267-419): 3.85e-48: 168: 23.08
+	Hs
		1079748 WWC2_HUMAN (163-315): 3.48e-35: 142: 24.18		EREP1_HUMAN (111-367): 3.33e-88: 284: 23.91
+	Hs
		1079794 WWOX_HUMAN (166-263): 7.4e-29: 120: 30.61		EREP1_HUMAN (111-367): 3.33e-88: 284: 23.91
+	Hs
		1079795 HECW2_HUMAN (13-303): 1.56e-14: 79: 14.79		EREP1_HUMAN (111-367): 3.33e-88: 284: 23.91