HitPredict

Interactor 1: CUL8 (P47050)
Cullin-8 (Cullin-C) (Regulator of Ty1 transposition protein 101)
Gene: RTT101

Interactor 2: RBX1 (Q08273)
RING-box protein HRT1 (RING-box protein 1) (E3 ubiquitin-protein ligase complex SCF subunit HRT1) (High level expression reduces Ty3 transposition protein 1) (Regulator of cullins protein 1)
Gene: HRT1

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.82 0.60 0.703

The method score is based on:

Property Details
Experiments 12676951, 11805837, 18719252, 19882662
Identification Methods coimmunoprecipitation, two hybrid, anti tag coimmunoprecipitation, affinity chromatography technology, pull down
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005634 - nucleus
GO:0005737 - cytoplasm
GO:0006275 - regulation of DNA replication
GO:0006334 - nucleosome assembly
GO:0016567 - protein ubiquitination
and 4 others

more...
Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 842
Sc

1 121
+ Mm
+ Hs
+ Mm
+ Hs
+ Hs
+ Ce
+ Mm
+ Hs
+ Hs
+ Ce
+ Dm
+ Dm
+ Sp
+ At
+ Hs
+ Mm
+ Dm
+ Hs
+ Hs
+ Hs

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Last updated: 15 Jul 2024