HitPredict

Interactor 1: GRIK2 (P39087)
Glutamate receptor ionotropic, kainate 2 (GluK2) (Glutamate receptor 6) (GluR-6) (GluR6) (Glutamate receptor beta-2) (GluR beta-2)
Gene: GRIK2

Interactor 2: Q8C825 (Q8C825)
Glutamate receptor ionotropic, kainate 1
Gene: Grik1

Species: Mus musculus

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	17174564
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	ANF_receptor~ANF_receptor, ANF_receptor~Lig_chan-Glu_bd, Lig_chan~Lig_chan-Glu_bd, Lig_chan-Glu_bd~Lig_chan-Glu_bd
Common GO terms	GO:0045211 - postsynaptic membrane
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 908 Mm			1 589
+	Hs
		811287 GRIK2_HUMAN (1-908): 0: 969: 99.01		GRIK1_HUMAN (1-587): 0: 610: 94.02
+	Rn
		652695 GRIK2_RAT (1-908): 0: 973: 99.89		GRIK1_RAT (1-587): 0: 594: 94.85
+	Hs
		1092399 GRIK2_HUMAN (1-908): 0: 969: 99.01		GRIK2_HUMAN (5-587): 0: 582: 75.51
+	Rn
		838432 GRIK2_RAT (1-908): 0: 973: 99.89		GRIK2_RAT (7-587): 0: 578: 75.21
+	Rn
		838433 GRIK2_RAT (1-908): 0: 973: 99.89		GRIK3_RAT (20-587): 0: 557: 71.80
+	Mm
		73013 GRIK2_MOUSE (1-908): 0: 973: 100.00		GRIK3_MOUSE (20-587): 0: 556: 71.45
+	Hs
		811288 GRIK3_HUMAN (6-908): 0: 902: 79.25		GRIK1_HUMAN (1-587): 0: 610: 94.02
+	Rn
		652696 GRIK3_RAT (6-908): 0: 900: 79.14		GRIK1_RAT (1-587): 0: 594: 94.85
+	Hs
		1092409 GRIK3_HUMAN (6-908): 0: 902: 79.25		GRIK3_HUMAN (19-587): 0: 559: 71.78
+	Hs
		838452 GRIK2_HUMAN (1-908): 0: 969: 99.01		GRIA1_HUMAN (16-587): 1.31e-162: 489: 34.54
+	Hs
		838490 GRIK2_HUMAN (1-908): 0: 969: 99.01		GRIA2_HUMAN (3-587): 3.2e-155: 469: 33.06
+	Mm
		811306 GRIK2_MOUSE (1-908): 0: 973: 100.00		GRIK4_MOUSE (14-587): 1.99e-146: 448: 35.75
+	Hs
		1092401 GRIK2_HUMAN (1-908): 0: 969: 99.01		GRIK4_HUMAN (14-587): 8.68e-146: 446: 35.23
+	Hs
		215877 GRIK2_HUMAN (1-908): 0: 969: 99.01		GRID2_HUMAN (18-568): 5.34e-144: 443: 25.09
+	Rn
		838436 GRIK2_RAT (1-908): 0: 973: 99.89		GRIK5_RAT (21-587): 8.64e-134: 416: 36.35
+	Hs
		1092402 GRIK2_HUMAN (1-908): 0: 969: 99.01		GRIK5_HUMAN (18-587): 7.62e-134: 416: 36.00
+	Hs
		1092410 GRIK3_HUMAN (6-908): 0: 902: 79.25		GRIK4_HUMAN (14-587): 8.68e-146: 446: 35.23
+	Mm
		771438 GRIK2_MOUSE (1-908): 0: 973: 100.00		NMDZ1_MOUSE (16-586): 3.43e-118: 374: 22.13
+	Hs
		1092411 GRIK3_HUMAN (6-908): 0: 902: 79.25		GRIK5_HUMAN (18-587): 7.62e-134: 416: 36.00