HitPredict

Interactor 1: CAPZB (P47756)
F-actin-capping protein subunit beta (CapZ beta)
Gene: CAPZB

Interactor 2: ARP10 (Q9NZ32)
Actin-related protein 10 (Actin-related protein 11) (hARP11)
Gene: ACTR10

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.62	1.00	0.789

Property	Details
Experiments	33961781, 35271311
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	Actin~F_actin_cap_B
Common GO terms	GO:0005829 - cytosol
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1 272 Hs			1 417
+	Hs
		813287 CAPZB_HUMAN (1-272): 4.35e-177: 490: 100.00		ACTB_HUMAN (10-384): 1.71e-173: 491: 23.94
+	Hs
		813366 CAPZB_HUMAN (1-272): 4.35e-177: 490: 100.00		ACTG_HUMAN (10-384): 2.53e-173: 491: 24.44
+	Hs
		813370 CAPZB_HUMAN (1-272): 4.35e-177: 490: 100.00		ACTC_HUMAN (7-384): 4e-172: 487: 24.51
+	Dm
		820547 CAPZB_DROME (1-269): 1.72e-166: 463: 81.78		ACT3_DROME (8-383): 6.35e-173: 489: 25.12
+	Dm
		820587 CAPZB_DROME (1-269): 1.72e-166: 463: 81.78		Q9VWE8_DROME (1-394): 1.1e-92: 285: 40.25