HitPredict

Interactor 1: KCNJ4 (P48050)
Inward rectifier potassium channel 4 (HIRK2) (HRK1) (Hippocampal inward rectifier) (HIR) (Inward rectifier K(+) channel Kir2.3) (IRK-3) (Potassium channel, inwardly rectifying subfamily J member 4)
Gene: KCNJ4

Interactor 2: DLG1 (Q12959)
Disks large homolog 1 (Synapse-associated protein 97) (SAP-97) (SAP97) (hDlg)
Gene: DLG1

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.69	0.60	0.646

Property	Details
Experiments	15024025, 14960569, 11181181
Identification Methods	affinity chromatography technology, pull down
Interaction Type	physical association, direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane GO:0016323 - basolateral plasma membrane
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 445 Hs			1 904
+	Hs
		1021490 KCJ12_HUMAN (7-445): 0: 660: 63.86		DLG1_HUMAN (1-904): 0: 725: 100.00
+	Hs
		80982 KCJ18_HUMAN (7-445): 0: 654: 63.41		DLG1_HUMAN (1-904): 0: 725: 100.00
+	Rn
		852397 KCJ12_RAT (7-445): 0: 648: 63.55		DLG1_RAT (1-904): 0: 701: 92.54
+	Hs
		1054724 KCJ12_HUMAN (7-445): 0: 660: 63.86		DLG3_HUMAN (139-904): 0: 585: 66.28
+	Rn
		852399 KCJ12_RAT (7-445): 0: 648: 63.55		DLG3_RAT (99-904): 0: 590: 64.57
+	Hs
		1054729 KCJ12_HUMAN (7-445): 0: 660: 63.86		PALS2_HUMAN (421-899): 2.36e-108: 346: 23.48
+	Hs
		159173 KCNJ4_HUMAN (1-445): 0: 690: 100.00		CSKP_HUMAN (19-360): 4.23e-28: 124: 10.64
+	Mm
		852403 KCNJ4_MOUSE (1-445): 0: 691: 96.86		DLG4_MOUSE (86-477): 2.03e-24: 111: 16.07
+	Hs
		816146 KCNJ4_HUMAN (1-445): 0: 690: 100.00		DLG4_HUMAN (86-493): 2.62e-24: 111: 15.64
+	Hs
		816149 KCNJ4_HUMAN (1-445): 0: 690: 100.00		SCRIB_HUMAN (217-396): 1.59e-23: 109: 41.49
+	Hs
		816150 KCNJ4_HUMAN (1-445): 0: 690: 100.00		DLG2_HUMAN (393-627): 7.26e-21: 100: 24.48
+	Hs
		159210 KCJ12_HUMAN (7-445): 0: 660: 63.86		CSKP_HUMAN (19-360): 4.23e-28: 124: 10.64
+	Rn
		852398 KCJ12_RAT (7-445): 0: 648: 63.55		CSKP_RAT (19-362): 1.15e-28: 125: 12.26
+	Hs
		942342 KCJ12_HUMAN (7-445): 0: 660: 63.86		DLG4_HUMAN (86-493): 2.62e-24: 111: 15.64
+	Hs
		1049947 KCJ12_HUMAN (7-445): 0: 660: 63.86		SCRIB_HUMAN (217-396): 1.59e-23: 109: 41.49
+	Mm
		1143540 Q9QYK8_MOUSE (9-439): 0: 657: 97.45		DLG4_MOUSE (86-477): 2.03e-24: 111: 16.07
+	Hs
		1054723 KCJ12_HUMAN (7-445): 0: 660: 63.86		DLG2_HUMAN (393-627): 7.26e-21: 100: 24.48
+	Rn
		677769 KCJ12_RAT (7-445): 0: 648: 63.55		DLG4_RAT (86-493): 2.93e-24: 111: 15.40
+	Hs
		929762 KCNJ2_HUMAN (7-445): 0: 641: 60.46		DLG4_HUMAN (86-493): 2.62e-24: 111: 15.64
+	Rn
		852400 KCJ12_RAT (7-445): 0: 648: 63.55		DLG2_RAT (393-627): 2.93e-21: 101: 24.48