HitPredict

Interactor 1: LIMS1 (P48059)
LIM and senescent cell antigen-like-containing domain protein 1 (Particularly interesting new Cys-His protein 1) (PINCH-1) (Renal carcinoma antigen NY-REN-48)
Gene: LIMS1

Interactor 2: ACTB (P60709)
Actin, cytoplasmic 1 (EC 3.6.4.-) (Beta-actin) [Cleaved into: Actin, cytoplasmic 1, N-terminally processed]
Gene: ACTB

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	30367047
Identification Methods	x-ray crystallography
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0005886 - plasma membrane GO:0005911 - cell-cell junction GO:0005925 - focal adhesion and 1 others more... GO:0019901 - protein kinase binding
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 325 Hs			1 375
+	Hs
		930016 PDLI7_HUMAN (191-324): 1.12e-35: 135: 29.85		ACTG_HUMAN (1-375): 0: 601: 98.93
+	Hs
		932996 ABLM2_HUMAN (2-171): 1.4e-30: 123: 24.18		ACTS_HUMAN (2-375): 0: 592: 93.58
+	Hs
		150545 ABLM1_HUMAN (3-146): 5.18e-26: 110: 22.92		ACTB_HUMAN (1-375): 0: 603: 100.00
+	Hs
		150554 ABLM1_HUMAN (3-146): 5.18e-26: 110: 22.92		ACTG_HUMAN (1-375): 0: 601: 98.93
+	Hs
		300997 ABLM3_HUMAN (179-323): 3.04e-25: 108: 22.97		ACTC_HUMAN (2-375): 0: 592: 94.12
+	Hs
		300998 ABLM3_HUMAN (179-323): 3.04e-25: 108: 22.97		ACTS_HUMAN (2-375): 0: 592: 93.58
+	Hs
		891971 PDLI5_HUMAN (247-317): 8.65e-13: 70.8: 33.80		ACTB_HUMAN (1-375): 0: 603: 100.00
+	Ce
		107572 G5EFG1_CAEEL (191-302): 1.15e-12: 70.5: 33.33		ACT2_CAEEL (2-375): 0: 600: 98.13
+	Ce
		107573 G5EFG1_CAEEL (191-302): 1.15e-12: 70.5: 33.33		ACT4_CAEEL (2-375): 0: 600: 97.59
+	Ce
		107571 G5EFG1_CAEEL (191-302): 1.15e-12: 70.5: 33.33		ACT3_CAEEL (2-375): 0: 598: 97.33
+	Mm
		915554 PDLI5_MOUSE (247-317): 1.66e-12: 70: 33.80		ACTA_MOUSE (2-375): 0: 591: 94.12