Interactor 1: SDF1 (P48061)
Stromal cell-derived factor 1 (SDF-1) (hSDF-1) (C-X-C motif chemokine 12) (Intercrine reduced in hepatomas) (IRH) (hIRH) (Pre-B cell growth-stimulating factor) (PBSF) [Cleaved into: SDF-1-beta(3-72); SDF-1-alpha(3-67)]
Gene: CXCL12

Interactor 2: SDF1 (P48061)
Stromal cell-derived factor 1 (SDF-1) (hSDF-1) (C-X-C motif chemokine 12) (Intercrine reduced in hepatomas) (IRH) (hIRH) (Pre-B cell growth-stimulating factor) (PBSF) [Cleaved into: SDF-1-beta(3-72); SDF-1-alpha(3-67)]
Gene: CXCL12

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.56 0.90 0.716

The method score is based on:

Property Details
Experiments 10954912, 28381538
Identification Methods x-ray crystallography, surface plasmon resonance
Interaction Type association, direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains IL8~IL8
Common GO terms GO:0001666 - response to hypoxia
GO:0001764 - neuron migration
GO:0001938 - positive regulation of endothelial cell proliferation
GO:0005102 - signaling receptor binding
GO:0005178 - integrin binding
and 44 others

more...

Homologous interactions 0

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024