Interactor 1: RPN3 (P40016)
26S proteasome regulatory subunit RPN3
Gene: RPN3

Interactor 2: RPN11 (P43588)
Ubiquitin carboxyl-terminal hydrolase RPN11 (EC 3.4.19.12) (26S proteasome regulatory subunit RPN11) (Protein MPR1)
Gene: RPN11

Species: Saccharomyces cerevisiae S288C

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.98 0.60 0.767

The method score is based on:

Property Details
Experiments 11805826, 16554755, 37968396, 16284124, 16338358, 22215586, 24038880, 26744777, 16429126, 26182356, 28106073, 26929360, 18314965, 19153599, 34161281, 27405762, 31601863, 31848235, 30792173, 15917626 and 8 others

more...

Identification Methods tandem affinity purification, affinity chromatography technology, biochemical, pull down, cross-linking study
Interaction Type physical association, association, direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0000502 - proteasome complex
GO:0008541 - proteasome regulatory particle, lid subcomplex
GO:0043161 - proteasome-mediated ubiquitin-dependent protein catabolic process
Homologous interactions 12

Homologous interactions

Color coding for hit scores

1 523
Sc

1 306
+ Hs
+ Dm
+ Sp
+ Sc
+ Dm
+ Hs
+ Hs
+ Zm
+ Dm
+ At
+ At
+ An

Service provided by Combinatics, Japan

Last updated: 11Aug2025