HitPredict

Interactor 1: SOX2 (P48431)
Transcription factor SOX-2
Gene: SOX2

Interactor 2: HNRH2 (P55795)
Heterogeneous nuclear ribonucleoprotein H2 (hnRNP H2) (FTP-3) (Heterogeneous nuclear ribonucleoprotein H') (hnRNP H') [Cleaved into: Heterogeneous nuclear ribonucleoprotein H2, N-terminally processed]
Gene: HNRNPH2

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	34732716
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005829 - cytosol
Homologous interactions	14

Homologous interactions

Color coding for hit scores

	1 317 Hs			1 449
+	Hs
		818011 SOX2_HUMAN (1-317): 2.16e-77: 240: 100.00		PABP4_HUMAN (1-447): 1.01e-81: 266: 13.59
+	Mm
		193430 SOX2_MOUSE (1-317): 8.01e-72: 226: 94.67		HNRH1_MOUSE (1-449): 5.42e-73: 238: 95.99
+	Hs
		817821 SOX2_HUMAN (1-317): 2.16e-77: 240: 100.00		HNRPF_HUMAN (1-434): 2.49e-60: 204: 71.72
+	Mm
		818781 SOX2_MOUSE (1-317): 8.01e-72: 226: 94.67		HNRPF_MOUSE (1-434): 3.55e-62: 208: 71.72
+	Hs
		682997 HM20A_HUMAN (6-248): 2.71e-37: 137: 15.32		HNRH1_HUMAN (1-449): 2.8e-73: 239: 96.21
+	Hs
		878714 CIC_HUMAN (3-272): 8.9e-33: 130: 22.26		HNRH2_HUMAN (1-449): 1.46e-74: 242: 100.00
+	Hs
		682945 CIC_HUMAN (3-272): 8.9e-33: 130: 22.26		HNRH1_HUMAN (1-449): 2.8e-73: 239: 96.21
+	Hs
		855180 CIC_HUMAN (3-272): 8.9e-33: 130: 22.26		HNRPF_HUMAN (1-434): 2.49e-60: 204: 71.72
+	Hs
		818064 SOX2_HUMAN (1-317): 2.16e-77: 240: 100.00		SART3_HUMAN (2-217): 3.71e-16: 83.3: 23.45
+	Hs
		817984 SOX2_HUMAN (1-317): 2.16e-77: 240: 100.00		GRSF1_HUMAN (268-361): 1.26e-15: 80.7: 23.47
+	Hs
		582131 SOX2_HUMAN (1-317): 2.16e-77: 240: 100.00		NUCL_HUMAN (4-404): 6.61e-09: 60.2: 18.16
+	Hs
		996634 SSRP1_HUMAN (24-203): 1.77e-31: 125: 15.68		GRSF1_HUMAN (268-361): 1.26e-15: 80.7: 23.47
+	Hs
		682586 SSRP1_HUMAN (24-203): 1.77e-31: 125: 15.68		HNRH3_HUMAN (10-86): 8.49e-10: 62.2: 33.77
+	Hs
		331720 NSD2_HUMAN (7-251): 1.34e-29: 120: 10.71		NUCL_HUMAN (4-404): 6.61e-09: 60.2: 18.16