Protein: IPO4
Importin-4 (Imp4) (Importin-4b) (Imp4b) (Ran-binding protein 4) (RanBP4)

Gene: IPO4
Organism: Homo sapiens
Interactions: 168
UniProt ID: Q8TEX9

Gene Ontology (top 5):
GO:0000785 - chromatin
GO:0005634 - nucleus
GO:0005737 - cytoplasm
GO:0006606 - protein import into nucleus
GO:0008139 - nuclear localization sequence binding

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

935019

H31
Histone H3.1

9

14

Small-scale

0.965

High

900728

RHOA
Transforming protein RhoA

3

6

High-throughput

0.817

High

919182

RAN
GTP-binding nuclear protein Ran

2

16

Small-scale

0.799

High

952488

H33
Histone H3.3

2

14

Small-scale

0.789

High

907419

RS8
Small ribosomal subunit protein eS8

5

1

High-throughput

0.718

High

1256995

ASF1A
Histone chaperone ASF1A

4

3

Small-scale

0.699

High

1256985

ASF1B
Histone chaperone ASF1B

4

3

Small-scale

0.697

High

1086236

H31T
Histone H3.1t

1

14

Small-scale

0.691

High

347415

MYC
Myc proto-oncogene protein

4

6

High-throughput

0.686

High

898405

RS3A
Small ribosomal subunit protein eS1

3

3

High-throughput

0.656

High

1256961

BAP1
Ubiquitin carboxyl-terminal hydrolase BAP1

3

5

Small-scale

0.650

High

791798

HD
Huntingtin

2

6

High-throughput

0.621

High

828313

CENPA
Histone H3-like centromeric protein A

1

14

High-throughput

0.618

High

894245

CDC42
Cell division control protein 42 homolog

1

7

High-throughput

0.618

High

918542

H2B1C
Histone H2B type 1-C/E/F/G/I

1

4

High-throughput

0.618

High

925464

RAC1
Ras-related C3 botulinum toxin substrate 1

1

6

High-throughput

0.618

High

1256974

UBE2O
(E3-independent) E2 ubiquitin-conjugating enzyme

1

2

High-throughput

0.618

High

917642

H4
Histone H4

2

5

High-throughput

0.611

High

1042125

CUL3
Cullin-3

2

7

High-throughput

0.611

High

1256960

DNJC9
DnaJ homolog subfamily C member 9

2

1

High-throughput

0.611

High

260586

TP4A3
Protein tyrosine phosphatase type IVA 3

2

19

High-throughput

0.601

High

779792

CCNF
Cyclin-F

2

6

High-throughput

0.601

High

455686

PARP1
Poly [ADP-ribose] polymerase 1

2

8

High-throughput

0.584

High

890764

PTEN
Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN

2

10

Small-scale

0.584

High

1237301

SIGL1
SIGLEC family-like protein 1

2

5

High-throughput

0.574

High

370073

ESR1
Estrogen receptor

2

7

High-throughput

0.571

High

246372

SCN2B
Sodium channel subunit beta-2

2

10

High-throughput

0.558

High

831912

CEBPD
CCAAT/enhancer-binding protein delta

1

8

Small-scale

0.554

High

160108

HGS
Hepatocyte growth factor-regulated tyrosine kinase substrate

2

2

High-throughput

0.553

High

261129

SH3L1
Adapter SH3BGRL

2

0

High-throughput

0.547

High

235973

HNRPQ
Heterogeneous nuclear ribonucleoprotein Q

1

2

High-throughput

0.536

High

529464

CFTR
Cystic fibrosis transmembrane conductance regulator

1

6

High-throughput

0.536

High

646243

STOM
Stomatin

1

5

High-throughput

0.536

High

796779

RANG
Ran-specific GTPase-activating protein

1

19

High-throughput

0.536

High

803664

BAG6
Large proline-rich protein BAG6

1

3

High-throughput

0.536

High

818288

SOX2
Transcription factor SOX-2

1

6

High-throughput

0.536

High

943137

KC1G2
Casein kinase I isoform gamma-2

1

6

High-throughput

0.536

High

957901

EFNB1
Ephrin-B1

1

5

High-throughput

0.536

High

1202513

CMTD1
Catechol O-methyltransferase domain-containing protein 1

1

6

High-throughput

0.536

High

1241900

ARRD4
Arrestin domain-containing protein 4

1

20

High-throughput

0.536

High

1252983

F174A
Membrane protein FAM174A

1

4

High-throughput

0.536

High

1256963

NEP1
Ribosomal RNA small subunit methyltransferase NEP1

1

1

High-throughput

0.536

High

1256971

FACD2
Fanconi anemia group D2 protein

1

5

Small-scale

0.536

High

1256976

SENP3
Sentrin-specific protease 3

1

6

High-throughput

0.536

High

666140

SHC1
SHC-transforming protein 1

2

7

High-throughput

0.521

High

1234537

SH2D3
SH2 domain-containing protein 3C

2

7

High-throughput

0.521

High

328905

TOP3B
DNA topoisomerase 3-beta-1

1

1

High-throughput

0.515

High

429921

CATL1
Procathepsin L

1

1

High-throughput

0.515

High

648838

DPP4
Dipeptidyl peptidase 4

1

2

High-throughput

0.515

High

1256980

BRF2
Transcription factor IIIB 50 kDa subunit

1

3

High-throughput

0.515

High

1256981

NEK6
Serine/threonine-protein kinase Nek6

1

7

High-throughput

0.515

High

308000

ZWINT
ZW10 interactor

1

0

High-throughput

0.513

High

351542

ANF
Natriuretic peptides A

1

0

High-throughput

0.513

High

580669

ML12A
Myosin regulatory light chain 12A

1

0

High-throughput

0.513

High

1127994

TOIP1
Torsin-1A-interacting protein 1

1

0

High-throughput

0.513

High

1219767

CDAN1
Codanin-1

1

0

Small-scale

0.513

High

1256970

RBM4
RNA-binding protein 4

1

0

High-throughput

0.513

High

1256973

B2L14
Apoptosis facilitator Bcl-2-like protein 14

1

0

High-throughput

0.513

High

855813

VAV2
Guanine nucleotide exchange factor VAV2

1

6

High-throughput

0.508

High

395305

A4
Amyloid-beta precursor protein

1

2

High-throughput

0.501

High

1256988

NXF1
Nuclear RNA export factor 1

1

6

Small-scale

0.501

High

364374

TFR1
Transferrin receptor protein 1

1

0

High-throughput

0.493

High

1256996

GSTK1
Glutathione S-transferase kappa 1

1

0

High-throughput

0.493

High

1256998

PHLA3
Pleckstrin homology-like domain family A member 3

1

0

High-throughput

0.493

High

238889

TPST2
Protein-tyrosine sulfotransferase 2

1

1

High-throughput

0.489

High

363236

FINC
Fibronectin

1

3

High-throughput

0.489

High

436938

ACM4
Muscarinic acetylcholine receptor M4

1

7

High-throughput

0.489

High

623550

AKAP5
A-kinase anchor protein 5

1

1

High-throughput

0.489

High

1067550

P2RY6
P2Y purinoceptor 6

1

10

High-throughput

0.489

High

1256972

TX101
Testis-expressed protein 101

1

2

High-throughput

0.489

High

1256999

NPTN
Neuroplastin

1

6

High-throughput

0.489

High

117018

SGK1
Serine/threonine-protein kinase Sgk1

1

3

High-throughput

0.479

High

158830

HAT1
Histone acetyltransferase type B catalytic subunit

1

1

Small-scale

0.479

High

282975

CIAO1
Probable cytosolic iron-sulfur protein assembly protein CIAO1

1

5

High-throughput

0.479

High

295048

RECQ4
ATP-dependent DNA helicase Q4

1

6

High-throughput

0.479

High

298674

UFL1
E3 UFM1-protein ligase 1

1

1

High-throughput

0.479

High

299428

UBXN7
UBX domain-containing protein 7

1

4

High-throughput

0.479

High

326720

SNAI1
Zinc finger protein SNAI1

1

11

High-throughput

0.479

High

338740

EGFR
Epidermal growth factor receptor

1

8

High-throughput

0.479

High

385221

NTRK1
High affinity nerve growth factor receptor

1

10

High-throughput

0.479

High

487610

ANDR
Androgen receptor

1

7

High-throughput

0.479

High

504459

HSP7C
Heat shock cognate 71 kDa protein

1

2

High-throughput

0.479

High

545006

AMPN
Aminopeptidase N

1

2

High-throughput

0.479

High

553268

RFA2
Replication protein A 32 kDa subunit

1

4

High-throughput

0.479

High

651772

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

6

High-throughput

0.479

High

684914

STIP1
Stress-induced-phosphoprotein 1

1

7

High-throughput

0.479

High

719357

PTN7
Tyrosine-protein phosphatase non-receptor type 7

1

12

High-throughput

0.479

High

742424

SYUA
Alpha-synuclein

1

3

High-throughput

0.479

High

750372

COIL
Coilin

1

2

High-throughput

0.479

High

824216

NR2C2
Nuclear receptor subfamily 2 group C member 2

1

1

High-throughput

0.479

High

879826

TPTE
Putative tyrosine-protein phosphatase TPTE

1

12

High-throughput

0.479

High

881539

ARL4C
ADP-ribosylation factor-like protein 4C

1

3

High-throughput

0.479

High

881654

PEX3
Peroxisomal biogenesis factor 3

1

1

High-throughput

0.479

High

903383

WDR5
WD repeat-containing protein 5

1

4

High-throughput

0.479

High

921358

RBX1
E3 ubiquitin-protein ligase RBX1

1

2

High-throughput

0.479

High

921660

GBB2
Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2

1

3

High-throughput

0.479

High

998909

EP300
Histone acetyltransferase p300

1

11

High-throughput

0.479

High

1018338

MERTK
Tyrosine-protein kinase Mer

1

8

High-throughput

0.479

High

1026328

AIMP2
Aminoacyl tRNA synthase complex-interacting multifunctional protein 2

1

3

High-throughput

0.479

High

1029667

TIF1B
Transcription intermediary factor 1-beta

1

8

High-throughput

0.479

High

1035919

BIRC3
Baculoviral IAP repeat-containing protein 3

1

5

High-throughput

0.479

High

1062175

HAPR1
HUWE1-associated protein modifying stress responses 1

1

4

High-throughput

0.479

High

1085320

FSCN1
Fascin

1

1

High-throughput

0.479

High

1087575

CAH9
Carbonic anhydrase 9

1

7

Small-scale

0.479

High

1108708

ANR55
Ankyrin repeat domain-containing protein 55

1

5

High-throughput

0.479

High

1135096

ACBD5
Acyl-CoA-binding domain-containing protein 5

1

1

High-throughput

0.479

High

1138817

MYSM1
Deubiquitinase MYSM1

1

2

Small-scale

0.479

High

1167724

TPTE2
Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase TPTE2

1

11

High-throughput

0.479

High

1170961

TRI67
Tripartite motif-containing protein 67

1

9

High-throughput

0.479

High

1188605

PARPT
Protein mono-ADP-ribosyltransferase TIPARP

1

4

High-throughput

0.479

High

1219200

Z3H7A
Zinc finger CCCH domain-containing protein 7A

1

7

High-throughput

0.479

High

1229816

SPICE
Spindle and centriole-associated protein 1

1

2

High-throughput

0.479

High

1256962

ESR2
Estrogen receptor beta

1

7

High-throughput

0.479

High

1256964

FBXW7
F-box/WD repeat-containing protein 7

1

4

Small-scale

0.479

High

1256965

DDRGK
DDRGK domain-containing protein 1

1

4

High-throughput

0.479

High

1256966

RUFY1
RUN and FYVE domain-containing protein 1

1

5

High-throughput

0.479

High

1256967

RING2
E3 ubiquitin-protein ligase RING2

1

7

High-throughput

0.479

High

1256968

DNJC7
DnaJ homolog subfamily C member 7

1

7

High-throughput

0.479

High

1256969

DUS23
Dual specificity protein phosphatase 23

1

16

High-throughput

0.479

High

1256975

Q9H4D1
Protein kinase

1

3

High-throughput

0.479

High

1256977

PKHA4
Pleckstrin homology domain-containing family A member 4

1

14

High-throughput

0.479

High

1256978

EGLN3
Prolyl hydroxylase EGLN3

1

3

High-throughput

0.479

High

1256983

SIR7
NAD-dependent protein deacetylase sirtuin-7

1

7

High-throughput

0.479

High

1256987

TLS1
Splicing factor C9orf78

1

5

High-throughput

0.479

High

1256989

ZRAN1
Ubiquitin thioesterase ZRANB1

1

13

High-throughput

0.479

High

1256990

TES
Testin

1

2

High-throughput

0.479

High

1256991

TBK1
Serine/threonine-protein kinase TBK1

1

4

High-throughput

0.479

High

1256993

CLC4E
C-type lectin domain family 4 member E

1

5

High-throughput

0.479

High

1256994

TRI33
E3 ubiquitin-protein ligase TRIM33

1

8

High-throughput

0.479

High

1256997

ZN330
Zinc finger protein 330

1

3

High-throughput

0.479

High

177952

TMPS2
Transmembrane protease serine 2

1

6

High-throughput

0.470

High

431255

CATB
Cathepsin B

1

2

High-throughput

0.470

High

637278

CATS
Cathepsin S

1

1

High-throughput

0.470

High

1198107

TM11B
Transmembrane protease serine 11B

1

6

High-throughput

0.470

High

1256959

CLC4D
C-type lectin domain family 4 member D

1

5

High-throughput

0.470

High

825722

MTR1B
Melatonin receptor type 1B

1

2

High-throughput

0.464

High

1086075

CDKN3
Cyclin-dependent kinase inhibitor 3

1

0

High-throughput

0.458

High

883576

RIPK4
Receptor-interacting serine/threonine-protein kinase 4

1

3

High-throughput

0.445

High

1023083

STK4
Serine/threonine-protein kinase 4

1

5

High-throughput

0.445

High

100996

APRIO
Alternative prion protein

1

4

High-throughput

0.437

High

129804

AGRIN
Agrin [Cleaved into: Agrin N-terminal 110 kDa subunit; Agrin C-terminal 110 kDa subunit; Agrin C-terminal 90 kDa fragment

1

3

High-throughput

0.437

High

179739

RPA34
DNA-directed RNA polymerase I subunit RPA34

1

2

High-throughput

0.437

High

329854

AGR2
Anterior gradient protein 2 homolog

1

2

High-throughput

0.437

High

572660

VGFR1
Vascular endothelial growth factor receptor 1

1

7

High-throughput

0.437

High

609441

FGFR3
Fibroblast growth factor receptor 3

1

14

High-throughput

0.437

High

674485

UFO
Tyrosine-protein kinase receptor UFO

1

9

High-throughput

0.437

High

720994

RFA3
Replication protein A 14 kDa subunit

1

4

High-throughput

0.437

High

729316

VGFR3
Vascular endothelial growth factor receptor 3

1

7

High-throughput

0.437

High

738245

FLT3
Receptor-type tyrosine-protein kinase FLT3

1

7

High-throughput

0.437

High

1101187

CL16A
Protein CLEC16A

1

2

High-throughput

0.437

High

1146655

A16L1
Autophagy-related protein 16-1

1

9

High-throughput

0.437

High

1165789

LMBRL
Protein LMBR1L

1

4

High-throughput

0.437

High

1166846

LRC31
Leucine-rich repeat-containing protein 31

1

2

High-throughput

0.437

High

1183869

KCTD9
BTB/POZ domain-containing protein KCTD9

1

4

High-throughput

0.437

High

1199649

ZN598
E3 ubiquitin-protein ligase ZNF598

1

5

High-throughput

0.437

High

1256982

ANLN
Anillin

1

8

High-throughput

0.437

High

1256986

B3GN2
N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase 2

1

3

High-throughput

0.437

High

48700

MED19
Mediator of RNA polymerase II transcription subunit 19

1

0

High-throughput

0.426

High

1256979

LN28A
Protein lin-28 homolog A

1

0

High-throughput

0.426

High

1256992

AGO2
Protein argonaute-2

1

0

High-throughput

0.426

High

1089

SIM26
Small integral membrane protein 26

1

4

High-throughput

0.407

High

90088

D6RAT0
Small ribosomal subunit protein eS1

1

3

High-throughput

0.407

High

1241541

MOT11
Monocarboxylate transporter 11

1

6

High-throughput

0.407

High

1203370

PRSR2
Proline and serine-rich protein 2

2

0

High-throughput

0.328

High

1256984

T11L1
T-complex protein 11-like protein 1

2

0

High-throughput

0.316

High

473066

BNIP5
Protein BNIP5

1

0

High-throughput

0.279

Low

1089437

ODAPH
Odontogenesis associated phosphoprotein

1

0

High-throughput

0.279

Low

1086676

CLPP
ATP-dependent Clp protease proteolytic subunit, mitochondrial

1

0

High-throughput

0.249

Low


Service provided by Combinatics, Japan

Last updated: 15 Jul 2024