Protein: NU188
Nucleoporin NUP188 (hNup188)

Gene: NU188, NUP188
Organism: Homo sapiens
Interactions: 149
UniProt ID: Q5SRE5

Gene Ontology (top 5):
GO:0005635 - nuclear envelope
GO:0005643 - nuclear pore
GO:0005829 - cytosol
GO:0006405 - RNA export from nucleus
GO:0006606 - protein import into nucleus

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

789131

NUP62
Nuclear pore glycoprotein p62

3

1

High-throughput

0.839

High

945246

NU107
Nuclear pore complex protein Nup107

1

0

High-throughput

0.656

High

1210361

SEH1
Nucleoporin SEH1

1

0

High-throughput

0.656

High

915973

NUP98
Nuclear pore complex protein Nup98-Nup96

1

2

Small-scale

0.647

High

285324

EED
Polycomb protein EED

1

1

High-throughput

0.618

High

487396

PARP1
Poly [ADP-ribose] polymerase 1

2

1

High-throughput

0.611

High

775553

NU214
Nuclear pore complex protein Nup214

2

1

Small-scale

0.611

High

1007708

RAE1L
mRNA export factor RAE1

1

0

High-throughput

0.586

High

1210335

NU188
Nucleoporin NUP188

1

0

High-throughput

0.586

High

1210355

NUP35
Nucleoporin NUP35

2

0

High-throughput

0.559

High

162004

MP2K7
Dual specificity mitogen-activated protein kinase kinase 7

1

1

High-throughput

0.536

High

409580

DPB1
HLA class II histocompatibility antigen, DP beta 1 chain

1

1

High-throughput

0.536

High

540031

BCR
Breakpoint cluster region protein

1

1

High-throughput

0.536

High

890336

NU153
Nuclear pore complex protein Nup153

1

3

High-throughput

0.536

High

1210367

NUP58
Nucleoporin p58/p45

1

1

High-throughput

0.536

High

563880

CFTR
Cystic fibrosis transmembrane conductance regulator

2

0

High-throughput

0.528

High

905590

IRAK1
Interleukin-1 receptor-associated kinase 1

1

0

High-throughput

0.513

High

981529

RAN
GTP-binding nuclear protein Ran

1

0

High-throughput

0.513

High

1100819

G3BP1
Ras GTPase-activating protein-binding protein 1

1

0

High-throughput

0.513

High

1134225

IMB1
Importin subunit beta-1

1

0

High-throughput

0.513

High

1140079

IQCB1
IQ calmodulin-binding motif-containing protein 1

1

0

High-throughput

0.513

High

1210348

CMTD1
Catechol O-methyltransferase domain-containing protein 1

1

0

High-throughput

0.513

High

1210352

SPC24
Kinetochore protein Spc24

1

0

High-throughput

0.513

High

1210362

AURKB
Aurora kinase B

1

0

High-throughput

0.513

High

1210378

LATS2
Serine/threonine-protein kinase LATS2

1

0

High-throughput

0.513

High

1210385

CILK1
Serine/threonine-protein kinase ICK

1

0

High-throughput

0.513

High

1210386

TN13B
Tumor necrosis factor ligand superfamily member 13B

1

0

High-throughput

0.513

High

1055056

TYRO3
Tyrosine-protein kinase receptor TYRO3

1

2

High-throughput

0.500

High

830878

CCNF
Cyclin-F

1

0

High-throughput

0.493

High

363392

EGFR
Epidermal growth factor receptor

1

0

High-throughput

0.479

High

58729

PTPC1
Protein tyrosine phosphatase domain-containing protein 1

1

1

High-throughput

0.479

High

157471

CTRO
Citron Rho-interacting kinase

1

1

High-throughput

0.479

High

172906

XPO1
Exportin-1

1

1

Small-scale

0.479

High

404118

GCR
Glucocorticoid receptor

1

1

Small-scale

0.479

High

520108

ANDR
Androgen receptor

1

1

High-throughput

0.479

High

541536

FGFR1
Fibroblast growth factor receptor 1

1

3

High-throughput

0.479

High

610006

VGFR1
Vascular endothelial growth factor receptor 1

1

2

High-throughput

0.479

High

719152

MPIP1
M-phase inducer phosphatase 1

1

1

High-throughput

0.479

High

719334

MPIP3
M-phase inducer phosphatase 3

1

1

High-throughput

0.479

High

858673

MP2K3
Dual specificity mitogen-activated protein kinase kinase 3

1

1

High-throughput

0.479

High

1010046

DLK1
Protein delta homolog 1

1

1

High-throughput

0.479

High

1210351

SIR6
NAD-dependent protein deacylase sirtuin-6

1

1

High-throughput

0.479

High

1210375

ECT2
Protein ECT2

1

1

High-throughput

0.479

High

1210382

ZRAN1
Ubiquitin thioesterase ZRANB1

1

1

High-throughput

0.479

High

277364

TP4A3
Protein tyrosine phosphatase type IVA 3

1

1

High-throughput

0.470

High

124369

HAX1
HCLS1-associated protein X-1

1

0

High-throughput

0.458

High

125489

LEG9
Galectin-9

1

0

High-throughput

0.458

High

129158

MEN1
Menin

1

0

High-throughput

0.458

High

159686

DVL2
Segment polarity protein dishevelled homolog DVL-2

1

0

High-throughput

0.458

High

179925

BET1
BET1 homolog

1

0

High-throughput

0.458

High

190943

RPA34
DNA-directed RNA polymerase I subunit RPA34

1

0

High-throughput

0.458

High

223111

PRC1
Protein regulator of cytokinesis 1

1

0

High-throughput

0.458

High

272245

OBSL1
Obscurin-like protein 1

1

0

High-throughput

0.458

High

291371

NU155
Nuclear pore complex protein Nup155

1

0

High-throughput

0.458

High

299228

FLOT1
Flotillin-1

1

0

High-throughput

0.458

High

315672

RECQ4
ATP-dependent DNA helicase Q4

1

0

High-throughput

0.458

High

345917

STAU1
Double-stranded RNA-binding protein Staufen homolog 1

1

0

High-throughput

0.458

High

436890

K1C18
Keratin, type I cytoskeletal 18

1

0

High-throughput

0.458

High

437206

K2C8
Keratin, type II cytoskeletal 8

1

0

High-throughput

0.458

High

565405

ITA4
Integrin alpha-4

1

0

High-throughput

0.458

High

643882

FBRL
rRNA 2'-O-methyltransferase fibrillarin

1

0

High-throughput

0.458

High

731376

STIP1
Stress-induced-phosphoprotein 1

1

0

High-throughput

0.458

High

766618

PHB1
Prohibitin 1

1

0

High-throughput

0.458

High

799927

COIL
Coilin

1

0

High-throughput

0.458

High

883567

CENPA
Histone H3-like centromeric protein A

1

0

High-throughput

0.458

High

920019

PLK1
Serine/threonine-protein kinase PLK1

1

0

High-throughput

0.458

High

941178

IF6
Eukaryotic translation initiation factor 6

1

0

High-throughput

0.458

High

941913

PEX3
Peroxisomal biogenesis factor 3

1

0

High-throughput

0.458

High

978987

RS6
Small ribosomal subunit protein eS6

1

0

High-throughput

0.458

High

979789

H4
Histone H4

1

0

High-throughput

0.458

High

984801

RL31
Large ribosomal subunit protein eL31

1

0

High-throughput

0.458

High

1064348

DEMA
Dematin

1

0

High-throughput

0.458

High

1106942

BIRC3
Baculoviral IAP repeat-containing protein 3

1

0

High-throughput

0.458

High

1107802

SQSTM
Sequestosome-1

1

0

High-throughput

0.458

High

1113311

CUL3
Cullin-3

1

0

High-throughput

0.458

High

1161484

IF16
Gamma-interferon-inducible protein 16

1

0

High-throughput

0.458

High

1210337

RN123
E3 ubiquitin-protein ligase RNF123

1

0

High-throughput

0.458

High

1210338

RNF43
E3 ubiquitin-protein ligase RNF43

1

0

High-throughput

0.458

High

1210342

BAKOR
Beclin 1-associated autophagy-related key regulator

1

0

High-throughput

0.458

High

1210345

HUWE1
E3 ubiquitin-protein ligase HUWE1

1

0

High-throughput

0.458

High

1210346

UBP48
Ubiquitin carboxyl-terminal hydrolase 48

1

0

Small-scale

0.458

High

1210349

DYR2
Dihydrofolate reductase 2, mitochondrial

1

0

High-throughput

0.458

High

1210358

AKAP1
A-kinase anchor protein 1, mitochondrial

1

0

High-throughput

0.458

High

1210360

DCPS
m7GpppX diphosphatase

1

0

High-throughput

0.458

High

1210363

CI072
Guanine nucleotide exchange factor C9orf72

1

0

High-throughput

0.458

High

1210365

RUFY1
RUN and FYVE domain-containing protein 1

1

0

High-throughput

0.458

High

1210371

CCDC8
Coiled-coil domain-containing protein 8

1

0

High-throughput

0.458

High

1210374

EGLN3
Prolyl hydroxylase EGLN3

1

0

High-throughput

0.458

High

1210380

KCMF1
E3 ubiquitin-protein ligase KCMF1

1

0

Small-scale

0.458

High

1210381

NXF1
Nuclear RNA export factor 1

1

0

Small-scale

0.458

High

1210387

ZN330
Zinc finger protein 330

1

0

High-throughput

0.458

High

174523

TRI66
Tripartite motif-containing protein 66

1

1

High-throughput

0.437

High

412056

NTRK1
High affinity nerve growth factor receptor

1

1

High-throughput

0.437

High

720253

UFO
Tyrosine-protein kinase receptor UFO

1

2

High-throughput

0.437

High

787032

FLT3
Receptor-type tyrosine-protein kinase FLT3

1

2

High-throughput

0.437

High

1052831

DUSP2
Dual specificity protein phosphatase 2

1

1

High-throughput

0.437

High

1099985

TIF1B
Transcription intermediary factor 1-beta

1

1

High-throughput

0.437

High

1101267

SLAF1
Signaling lymphocytic activation molecule

1

1

High-throughput

0.437

High

1210366

DUS26
Dual specificity protein phosphatase 26

1

1

High-throughput

0.437

High

1210377

SIR7
NAD-dependent protein deacetylase sirtuin-7

1

1

High-throughput

0.437

High

380058

HLAB
HLA class I histocompatibility antigen, B alpha chain

1

0

High-throughput

0.426

High

664876

RAE1
Rab proteins geranylgeranyltransferase component A 1

1

0

High-throughput

0.426

High

854537

S15A1
Solute carrier family 15 member 1

1

0

High-throughput

0.426

High

1209213

LRRK2
Leucine-rich repeat serine/threonine-protein kinase 2

1

0

High-throughput

0.426

High

1210340

S27A4
Long-chain fatty acid transport protein 4

1

0

High-throughput

0.426

High

1210369

ZDHC5
Palmitoyltransferase ZDHHC5

1

0

High-throughput

0.426

High

166315

ZNT4
Probable proton-coupled zinc antiporter SLC30A4

1

1

High-throughput

0.407

High

1210339

ZNT6
Zinc transporter 6

1

1

High-throughput

0.407

High

1210356

S35G2
Solute carrier family 35 member G2

1

1

High-throughput

0.407

High

619833

VCAM1
Vascular cell adhesion protein 1

2

0

High-throughput

0.313

High

622463

ELK1
ETS domain-containing protein Elk-1

2

0

High-throughput

0.298

High

292357

RA51D
DNA repair protein RAD51 homolog 4

1

0

High-throughput

0.279

Low

821724

CD79B
B-cell antigen receptor complex-associated protein beta chain

1

0

High-throughput

0.279

Low

922316

LIMK2
LIM domain kinase 2

1

0

High-throughput

0.279

Low

1160943

PDK4
[Pyruvate dehydrogenase

1

0

High-throughput

0.279

Low

1210347

ST32C
Serine/threonine-protein kinase 32C

1

0

High-throughput

0.279

Low

1210350

SLX4
Structure-specific endonuclease subunit SLX4

1

0

High-throughput

0.279

Low

1210354

HIPK4
Homeodomain-interacting protein kinase 4

1

0

High-throughput

0.279

Low

1210357

NEK7
Serine/threonine-protein kinase Nek7

1

0

High-throughput

0.279

Low

1210364

PSKH2
Serine/threonine-protein kinase H2

1

0

High-throughput

0.279

Low

1210373

SG196
Protein O-mannose kinase

1

0

High-throughput

0.279

Low

1210388

RPKL1
Ribosomal protein S6 kinase-like 1

1

0

High-throughput

0.279

Low

1210383

MD2L2
Mitotic spindle assembly checkpoint protein MAD2B

1

0

High-throughput

0.269

Low

218282

TGON2
Trans-Golgi network integral membrane protein 2

1

0

High-throughput

0.249

Low

247955

NUPR1
Nuclear protein 1

1

0

High-throughput

0.249

Low

342209

BRD1
Bromodomain-containing protein 1

1

0

High-throughput

0.249

Low

372233

MYC
Myc proto-oncogene protein

1

0

High-throughput

0.249

Low

451397

NFM
Neurofilament medium polypeptide

1

0

High-throughput

0.249

Low

588870

RFA2
Replication protein A 32 kDa subunit

1

0

High-throughput

0.249

Low

680715

CATS
Cathepsin S

1

0

High-throughput

0.249

Low

695650

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

0

High-throughput

0.249

Low

768372

RFA3
Replication protein A 14 kDa subunit

1

0

High-throughput

0.249

Low

851775

NKX21
Homeobox protein Nkx-2.1

1

0

High-throughput

0.249

Low

1004671

RNF4
E3 ubiquitin-protein ligase RNF4

1

0

High-throughput

0.249

Low

1135703

HAPR1
HUWE1-associated protein modifying stress responses 1

1

0

High-throughput

0.249

Low

1210341

LMBRL
Protein LMBR1L

1

0

High-throughput

0.249

Low

1210343

TRI67
Tripartite motif-containing protein 67

1

0

High-throughput

0.249

Low

1210344

PARPT
Protein mono-ADP-ribosyltransferase TIPARP

1

0

High-throughput

0.249

Low

1210359

PTPR2
Receptor-type tyrosine-protein phosphatase N2

1

0

High-throughput

0.249

Low

1210368

MK67I
MKI67 FHA domain-interacting nucleolar phosphoprotein

1

0

High-throughput

0.249

Low

1210370

RPA49
DNA-directed RNA polymerase I subunit RPA49

1

0

High-throughput

0.249

Low

1210372

PKHA4
Pleckstrin homology domain-containing family A member 4

1

0

High-throughput

0.249

Low

1210376

MET14
N(6)-adenosine-methyltransferase non-catalytic subunit METTL14

1

0

High-throughput

0.249

Low

1210379

F120C
Constitutive coactivator of PPAR-gamma-like protein 2

1

0

High-throughput

0.249

Low

653365

HEMH
Ferrochelatase, mitochondrial

1

0

High-throughput

0.232

Low

1210336

S35F1
Solute carrier family 35 member F1

1

0

High-throughput

0.232

Low

1210353

MOT11
Monocarboxylate transporter 11

1

0

High-throughput

0.232

Low

1210384

TTC7A
Tetratricopeptide repeat protein 7A

1

0

Small-scale

0.232

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025