HitPredict

Interactor 1: PP1B (P48462)
Serine/threonine-protein phosphatase beta isoform (EC 3.1.3.16) (Protein flap wing)
Gene: flw

Interactor 2: SMO (P91682)
Protein smoothened (dSMO) (SMOH) (Smooth)
Gene: SMO

Species: Drosophila melanogaster

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	21730325
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0007476 - imaginal disc-derived wing morphogenesis
Homologous interactions	12

Homologous interactions

Color coding for hit scores

	1 330 Dm			1 1036
+	Dm
		819205 PP11_DROME (1-330): 0: 563: 81.21		SMO_DROME (1-1036): 0: 1567: 100.00
+	Dm
		524610 PP12_DROME (1-303): 0: 548: 85.48		SMO_DROME (1-1036): 0: 1567: 100.00
+	Dm
		954738 PP13_DROME (6-303): 0: 542: 85.57		SMO_DROME (1-1036): 0: 1567: 100.00
+	Hs
		906532 PP1B_HUMAN (1-329): 0: 581: 88.75		SFRP1_HUMAN (91-250): 3.54e-41: 156: 18.41
+	Hs
		737920 PP1G_HUMAN (1-330): 0: 572: 82.48		SFRP1_HUMAN (91-250): 3.54e-41: 156: 18.41
+	Hs
		906019 PP1A_HUMAN (1-326): 0: 570: 82.73		SFRP1_HUMAN (91-250): 3.54e-41: 156: 18.41
+	Hs
		906559 PP1B_HUMAN (1-329): 0: 581: 88.75		SFRP2_HUMAN (86-204): 4.57e-36: 140: 21.31
+	Hs
		906488 PP1B_HUMAN (1-329): 0: 581: 88.75		SFRP5_HUMAN (91-199): 4.19e-35: 138: 17.86
+	Hs
		737974 PP1G_HUMAN (1-330): 0: 572: 82.48		SFRP2_HUMAN (86-204): 4.57e-36: 140: 21.31
+	Hs
		737855 PP1G_HUMAN (1-330): 0: 572: 82.48		SFRP5_HUMAN (91-199): 4.19e-35: 138: 17.86
+	Hs
		906078 PP1A_HUMAN (1-326): 0: 570: 82.73		SFRP2_HUMAN (86-204): 4.57e-36: 140: 21.31
+	Hs
		905956 PP1A_HUMAN (1-326): 0: 570: 82.73		SFRP5_HUMAN (91-199): 4.19e-35: 138: 17.86