HitPredict

Interactor 1: PRS4 (P48601)
26S proteasome regulatory subunit 4 (P26s4)
Gene: Rpt2

Interactor 2: PSB4 (Q9VNA5)
Proteasome subunit beta type-4 (Proteasome subunit beta type-7)
Gene: Prosbeta7

Species: Drosophila melanogaster

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	22036573
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	AAA~Proteasome, AAA_lid_3~Proteasome
Common GO terms	GO:0005654 - nucleoplasm GO:0005829 - cytosol GO:0043161 - proteasome-mediated ubiquitin-dependent protein catabolic process
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 439 Dm			1 268
+	Sc
		675482 PRS10_YEAST (9-436): 8.69e-144: 419: 37.82		PSB7_YEAST (31-268): 1.61e-86: 260: 35.41
+	Sc
		675428 PRS10_YEAST (9-436): 8.69e-144: 419: 37.82		PSB5_YEAST (21-268): 4.31e-80: 244: 15.08
+	Hs
		156269 PRS4_HUMAN (24-439): 8.92e-138: 404: 92.55		PSA7_HUMAN (33-265): 2.53e-82: 248: 12.55
+	Dm
		574017 PRS4_DROME (1-439): 7.01e-141: 411: 100.00		PSA4_DROME (33-268): 1.36e-78: 240: 14.34
+	Dm
		611634 PRS4_DROME (1-439): 7.01e-141: 411: 100.00		PSA71_DROME (32-265): 1.61e-77: 236: 12.50
+	Dm
		820495 PRS4_DROME (1-439): 7.01e-141: 411: 100.00		PSA5_DROME (33-266): 1.46e-77: 236: 17.00
+	Hs
		638104 PRS4_HUMAN (24-439): 8.92e-138: 404: 92.55		PSA4_HUMAN (32-265): 3.42e-79: 241: 13.33
+	Hs
		893639 PRS4_HUMAN (24-439): 8.92e-138: 404: 92.55		PSA6_HUMAN (28-265): 1.4e-78: 239: 17.55
+	Hs
		656441 PRS4_HUMAN (24-439): 8.92e-138: 404: 92.55		PSB4_HUMAN (12-268): 4.95e-78: 238: 38.91
+	Hs
		656193 PRS4_HUMAN (24-439): 8.92e-138: 404: 92.55		PSA5_HUMAN (33-266): 7.04e-78: 237: 17.96
+	Dm
		820480 PRS4_DROME (1-439): 7.01e-141: 411: 100.00		Q7K148_DROME (56-252): 1.88e-69: 217: 20.31
+	Dm
		820525 PRS4_DROME (1-439): 7.01e-141: 411: 100.00		Q9VUJ1_DROME (60-260): 6.76e-69: 215: 19.40
+	Sc
		625948 PRS10_YEAST (9-436): 8.69e-144: 419: 37.82		PSB2_YEAST (50-268): 2.12e-65: 206: 19.09
+	Hs
		656694 PRS4_HUMAN (24-439): 8.92e-138: 404: 92.55		PSB5_HUMAN (15-247): 2.34e-71: 221: 18.03
+	Hs
		906905 PRS4_HUMAN (24-439): 8.92e-138: 404: 92.55		PSB7_HUMAN (23-260): 1.37e-69: 217: 19.58
+	Hs
		594501 PRS4_HUMAN (24-439): 8.92e-138: 404: 92.55		PSB1_HUMAN (22-248): 5.77e-66: 207: 19.66
+	Dm
		771398 PRS4_DROME (1-439): 7.01e-141: 411: 100.00		PSB1_DROME (29-251): 2.59e-58: 187: 23.08
+	Dm
		820515 PRS4_DROME (1-439): 7.01e-141: 411: 100.00		Q9VJJ0_DROME (59-257): 1.07e-21: 91.3: 19.60
+	Dm
		47601 PRS4_DROME (1-439): 7.01e-141: 411: 100.00		A0AQH0_DROME (50-248): 6.38e-21: 89.8: 16.08
+	Hs
		832083 PRS4_HUMAN (24-439): 8.92e-138: 404: 92.55		PSB2_HUMAN (60-247): 7.94e-21: 89: 20.75