Protein: MAGA3
Melanoma-associated antigen 3 (Antigen MZ2-D) (Cancer/testis antigen 1.3) (CT1.3) (MAGE-3 antigen)

Gene: MAGA3, MAGEA3
Organism: Homo sapiens
Interactions: 133
UniProt ID: P43357

Gene Ontology (top 5):
GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0005634 - nucleus
GO:0005783 - endoplasmic reticulum
GO:0010507 - negative regulation of autophagy
GO:0010955 - negative regulation of protein processing

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

848221

MAGA6
Melanoma-associated antigen 6

2

14

Small-scale

0.789

High

848252

TIF1B
Transcription intermediary factor 1-beta

4

20

Small-scale

0.701

High

848194

MAGA2
Melanoma-associated antigen 2

1

14

High-throughput

0.691

High

191903

MAGB4
Melanoma-associated antigen B4

1

17

Small-scale

0.618

High

848222

MAGA8
Melanoma-associated antigen 8

1

14

Small-scale

0.618

High

848289

STALP
AMSH-like protease

3

1

High-throughput

0.610

High

444929

S10A9
Protein S100-A9

2

5

High-throughput

0.606

High

843359

HD
Huntingtin

2

4

Small-scale

0.606

High

848297

RUSC1
AP-4 complex accessory subunit RUSC1

2

3

High-throughput

0.606

High

848310

LSM2
U6 snRNA-associated Sm-like protein LSm2

2

2

High-throughput

0.606

High

848225

PCY1A
Choline-phosphate cytidylyltransferase A

2

0

High-throughput

0.580

High

848298

CINP
Cyclin-dependent kinase 2-interacting protein

2

0

High-throughput

0.580

High

848251

AAPK1
5'-AMP-activated protein kinase catalytic subunit alpha-1

1

2

Small-scale

0.561

High

848290

DCAF5
DDB1- and CUL4-associated factor 5

2

8

Small-scale

0.558

High

123342

BACH
Cytosolic acyl coenzyme A thioester hydrolase

2

3

High-throughput

0.553

High

137197

EXOC5
Exocyst complex component 5

2

1

High-throughput

0.553

High

848278

KIF27
Kinesin-like protein KIF27

2

6

High-throughput

0.553

High

848296

BCL7B
B-cell CLL/lymphoma 7 protein family member B

2

1

High-throughput

0.553

High

848274

CASPC
Inactive caspase-12

1

1

Small-scale

0.552

High

243567

SMCA5
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 5

1

5

High-throughput

0.536

High

352084

MBD3
Methyl-CpG-binding domain protein 3

1

1

High-throughput

0.536

High

487984

DPOLA
DNA polymerase alpha catalytic subunit

1

1

High-throughput

0.536

High

557162

SRC
Proto-oncogene tyrosine-protein kinase Src

1

3

High-throughput

0.536

High

703278

SMCA1
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 1

1

5

High-throughput

0.536

High

848224

CENPF
Centromere protein F

1

18

High-throughput

0.536

High

848247

BPTF
Nucleosome-remodeling factor subunit BPTF

1

13

High-throughput

0.536

High

848262

CHD4
Chromodomain-helicase-DNA-binding protein 4

1

5

High-throughput

0.536

High

848275

ACD11
Acyl-CoA dehydrogenase family member 11

1

1

High-throughput

0.536

High

848287

P66B
Transcriptional repressor p66-beta

1

1

High-throughput

0.536

High

848284

SCPDL
Saccharopine dehydrogenase-like oxidoreductase

1

0

High-throughput

0.513

High

135539

DNM1L
Dynamin-1-like protein

1

2

Small-scale

0.508

High

539870

RALB
Ras-related protein Ral-B

1

2

High-throughput

0.489

High

848234

RAP1A
Ras-related protein Rap-1A

1

2

High-throughput

0.489

High

848253

GRB10
Growth factor receptor-bound protein 10

1

5

High-throughput

0.489

High

848260

I5P1
Inositol polyphosphate-5-phosphatase A

1

1

High-throughput

0.489

High

848271

GRTP1
Growth hormone-regulated TBC protein 1

1

2

High-throughput

0.489

High

848282

MICU2
Calcium uptake protein 2, mitochondrial

1

4

High-throughput

0.489

High

848306

HMGX4
HMG domain-containing protein 4

1

5

High-throughput

0.489

High

848307

PACN3
Protein kinase C and casein kinase substrate in neurons protein 3

1

1

High-throughput

0.489

High

848308

CP131
Centrosomal protein of 131 kDa

1

9

High-throughput

0.489

High

133970

IPO5
Importin-5

1

7

Small-scale

0.479

High

290887

PPM1B
Protein phosphatase 1B

1

2

Small-scale

0.479

High

389979

ALBU
Albumin

1

1

Small-scale

0.479

High

407408

K2C1
Keratin, type II cytoskeletal 1

1

4

Small-scale

0.479

High

457291

TBB5
Tubulin beta chain

1

10

Small-scale

0.479

High

468159

HS90B
Heat shock protein HSP 90-beta

1

7

Small-scale

0.479

High

507107

UBB
Polyubiquitin-B [Cleaved into: Ubiquitin]

1

4

Small-scale

0.479

High

507653

UBC
Polyubiquitin-C [Cleaved into: Ubiquitin]

1

4

Small-scale

0.479

High

608486

DDX5
Probable ATP-dependent RNA helicase DDX5

1

6

Small-scale

0.479

High

729170

HNRH1
Heterogeneous nuclear ribonucleoprotein H

1

12

Small-scale

0.479

High

771965

K1C9
Keratin, type I cytoskeletal 9

1

8

Small-scale

0.479

High

838013

STAT1
Signal transducer and activator of transcription 1-alpha/beta

1

2

Small-scale

0.479

High

841640

LPPRC
Leucine-rich PPR motif-containing protein, mitochondrial

1

2

Small-scale

0.479

High

848226

RBP2
E3 SUMO-protein ligase RanBP2

1

3

Small-scale

0.479

High

848228

HNRPM
Heterogeneous nuclear ribonucleoprotein M

1

7

Small-scale

0.479

High

848230

TERA
Transitional endoplasmic reticulum ATPase

1

3

Small-scale

0.479

High

848231

HNRH2
Heterogeneous nuclear ribonucleoprotein H2

1

11

Small-scale

0.479

High

848232

ACTB
Actin, cytoplasmic 1

1

6

Small-scale

0.479

High

848233

PRS4
26S proteasome regulatory subunit 4

1

3

Small-scale

0.479

High

848235

ACTG
Actin, cytoplasmic 2

1

6

Small-scale

0.479

High

848237

EF1A1
Elongation factor 1-alpha 1

1

5

Small-scale

0.479

High

848238

GTF2I
General transcription factor II-I

1

3

Small-scale

0.479

High

848240

HNRPU
Heterogeneous nuclear ribonucleoprotein U

1

7

Small-scale

0.479

High

848241

DSG1
Desmoglein-1

1

3

Small-scale

0.479

High

848243

PRDX1
Peroxiredoxin-1

1

4

Small-scale

0.479

High

848245

DHX9
ATP-dependent RNA helicase A

1

8

Small-scale

0.479

High

848254

HDAC1
Histone deacetylase 1

1

9

Small-scale

0.479

High

848255

KCC2D
Calcium/calmodulin-dependent protein kinase type II subunit delta

1

6

Small-scale

0.479

High

848256

SNW1
SNW domain-containing protein 1

1

2

Small-scale

0.479

High

848259

RCN2
Reticulocalbin-2

1

2

Small-scale

0.479

High

848263

IMB1
Importin subunit beta-1

1

7

Small-scale

0.479

High

848266

DDB1
DNA damage-binding protein 1

1

1

Small-scale

0.479

High

848267

FILA2
Filaggrin-2

1

5

Small-scale

0.479

High

848269

DCA12
DDB1- and CUL4-associated factor 12

1

1

Small-scale

0.479

High

848276

EPMIP
EPM2A-interacting protein 1

1

2

Small-scale

0.479

High

848283

CCAR2
Cell cycle and apoptosis regulator protein 2

1

3

Small-scale

0.479

High

848285

UBA3
NEDD8-activating enzyme E1 catalytic subunit

1

2

Small-scale

0.479

High

848286

IASPP
RelA-associated inhibitor

1

11

Small-scale

0.479

High

848295

TBA1C
Tubulin alpha-1C chain

1

16

Small-scale

0.479

High

848301

MYLK2
Myosin light chain kinase 2, skeletal/cardiac muscle

1

6

Small-scale

0.479

High

848305

FBLN5
Fibulin-5

1

3

Small-scale

0.479

High

848309

RUVB2
RuvB-like 2

1

2

Small-scale

0.479

High

848312

YTHD2
YTH domain-containing family protein 2

1

3

Small-scale

0.479

High

2939

A0A0C4DGT3
Epididymis secretory sperm binding protein

1

2

High-throughput

0.470

High

210882

PSMD3
26S proteasome non-ATPase regulatory subunit 3

1

0

Small-scale

0.458

High

348409

AIFM1
Apoptosis-inducing factor 1, mitochondrial

1

0

Small-scale

0.458

High

701109

PSB5
Proteasome subunit beta type-5

1

0

Small-scale

0.458

High

848280

TDRP
Testis development-related protein

1

0

Small-scale

0.458

High

848293

PSMD1
26S proteasome non-ATPase regulatory subunit 1

1

0

Small-scale

0.458

High

848294

CPNE1
Copine-1

1

0

Small-scale

0.458

High

848299

PDIP3
Polymerase delta-interacting protein 3

1

0

Small-scale

0.458

High

848265

ENOX2
Ecto-NOX disulfide-thiol exchanger 2

1

1

High-throughput

0.439

High

848273

IQEC1
IQ motif and SEC7 domain-containing protein 1

1

2

High-throughput

0.439

High

128170

PSD12
26S proteasome non-ATPase regulatory subunit 12

1

1

Small-scale

0.437

High

244138

KIF5C
Kinesin heavy chain isoform 5C

1

5

Small-scale

0.437

High

270326

WDR1
WD repeat-containing protein 1

1

8

Small-scale

0.437

High

412940

CPNS1
Calpain small subunit 1

1

3

Small-scale

0.437

High

532432

CH60
60 kDa heat shock protein, mitochondrial

1

2

Small-scale

0.437

High

593818

PP2BB
Serine/threonine-protein phosphatase 2B catalytic subunit beta isoform

1

2

Small-scale

0.437

High

621446

HXK1
Hexokinase-1

1

3

Small-scale

0.437

High

680264

ATPA
ATP synthase F(1) complex subunit alpha, mitochondrial

1

2

Small-scale

0.437

High

786017

LONM
Lon protease homolog, mitochondrial

1

2

Small-scale

0.437

High

848223

RS5
Small ribosomal subunit protein uS7

1

1

Small-scale

0.437

High

848227

TCPQ
T-complex protein 1 subunit theta

1

7

Small-scale

0.437

High

848229

HXK2
Hexokinase-2

1

3

Small-scale

0.437

High

848236

ACTC
Actin, alpha cardiac muscle 1

1

5

Small-scale

0.437

High

848242

EF1A2
Elongation factor 1-alpha 2

1

5

Small-scale

0.437

High

848244

PP2BA
Protein phosphatase 3 catalytic subunit alpha

1

3

Small-scale

0.437

High

848246

FBLN3
EGF-containing fibulin-like extracellular matrix protein 1

1

3

Small-scale

0.437

High

848248

KIF5A
Kinesin heavy chain isoform 5A

1

7

Small-scale

0.437

High

848250

TRAP1
Heat shock protein 75 kDa, mitochondrial

1

3

Small-scale

0.437

High

848261

PUM1
Pumilio homolog 1

1

3

Small-scale

0.437

High

848264

UBE3C
Ubiquitin-protein ligase E3C

1

13

Small-scale

0.437

High

848268

ATD3C
ATPase family AAA domain-containing protein 3C

1

4

Small-scale

0.437

High

848270

ATD3B
ATPase family AAA domain-containing protein 3B

1

7

Small-scale

0.437

High

848277

YTHD3
YTH domain-containing family protein 3

1

3

Small-scale

0.437

High

848279

LIPB1
Liprin-beta-1

1

10

Small-scale

0.437

High

848292

MA7D2
MAP7 domain-containing protein 2

1

3

Small-scale

0.437

High

848300

RBNS5
Rabenosyn-5

1

3

Small-scale

0.437

High

848303

VPS45
Vacuolar protein sorting-associated protein 45

1

1

Small-scale

0.437

High

848311

TLN1
Talin-1

1

11

Small-scale

0.437

High

848272

A16L1
Autophagy-related protein 16-1

1

10

High-throughput

0.407

High

848281

BAP18
BPTF-associated chromatin complex component 1

3

0

High-throughput

0.346

High

64690

PALM3
Paralemmin-3

1

0

High-throughput

0.279

Low

848249

CNTN1
Contactin-1

1

0

High-throughput

0.279

Low

848257

EFR3A
Protein EFR3 homolog A

1

0

High-throughput

0.279

Low

848258

DPOA2
DNA polymerase alpha subunit B

1

0

High-throughput

0.279

Low

848302

CA021
Uncharacterized protein C1orf21

1

0

High-throughput

0.279

Low

301857

CLPX
ATP-dependent clpX-like chaperone, mitochondrial

1

0

Small-scale

0.249

Low

848239

DCD
Dermcidin

1

0

Small-scale

0.249

Low

848288

KPBB
Phosphorylase b kinase regulatory subunit beta

1

0

Small-scale

0.249

Low

848291

VPS35
Vacuolar protein sorting-associated protein 35

1

0

Small-scale

0.249

Low

848304

NDUF4
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 4

1

0

Small-scale

0.249

Low


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Last updated: 11Aug2025