HitPredict

Interactor 1: CEAM6 (P40199)
Cell adhesion molecule CEACAM6 (Carcinoembryonic antigen-related cell adhesion molecule 6) (CEA cell adhesion molecule 6) (Non-specific crossreacting antigen) (Normal cross-reacting antigen) (CD antigen CD66c)
Gene: CEACAM6

Interactor 2: CEAM6 (P40199)
Cell adhesion molecule CEACAM6 (Carcinoembryonic antigen-related cell adhesion molecule 6) (CEA cell adhesion molecule 6) (Non-specific crossreacting antigen) (Normal cross-reacting antigen) (CD antigen CD66c)
Gene: CEACAM6

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.86 1.00 0.930

The method score is based on:

Property Details
Experiments 32296183, 39468006, 21982860, unassigned1304, 26483485
Identification Methods two hybrid, proximity labelling technology, pull down, two hybrid prey pooling approach, two hybrid array, validated two hybrid, x-ray crystallography, cosedimentation in solution, protein array
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains Ig_2~Ig_2, Ig_2~Ig_3, Ig_2~V-set, Ig_3~Ig_3, Ig_3~V-set, V-set~V-set
Common GO terms GO:0005615 - extracellular space
GO:0005886 - plasma membrane
GO:0006915 - apoptotic process
GO:0007156 - homophilic cell adhesion via plasma membrane adhesion molecules
GO:0007157 - heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules
and 11 others

more...
Homologous interactions 17

Homologous interactions

Color coding for hit scores

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Last updated: 11Aug2025