HitPredict

Interactor 1: CEAM6 (P40199)
Cell adhesion molecule CEACAM6 (Carcinoembryonic antigen-related cell adhesion molecule 6) (CEA cell adhesion molecule 6) (Non-specific crossreacting antigen) (Normal cross-reacting antigen) (CD antigen CD66c)
Gene: CEACAM6

Interactor 2: CEAM7 (Q14002)
Cell adhesion molecule CEACAM7 (Carcinoembryonic antigen CGM2) (Carcinoembryonic antigen-related cell adhesion molecule 7) (CEA cell adhesion molecule 7)
Gene: CEACAM7

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.52	1.00	0.724

Property	Details
Experiments	21982860
Identification Methods	pull down, protein array
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	Ig_2~Ig_3, Ig_2~V-set, Ig_3~Ig_3, Ig_3~V-set, V-set~V-set
Common GO terms	GO:0005886 - plasma membrane GO:0009986 - cell surface GO:0016324 - apical plasma membrane GO:0098552 - side of membrane
Homologous interactions	17

Homologous interactions

Color coding for hit scores

	1 344 Hs			1 265
+	Hs
		567235 CEAM6_HUMAN (1-344): 3.04e-83: 257: 100.00		CEAM1_HUMAN (3-265): 2.27e-40: 147: 24.72
+	Hs
		567234 CEAM8_HUMAN (1-344): 8.84e-74: 233: 78.22		CEAM1_HUMAN (3-265): 2.27e-40: 147: 24.72
+	Hs
		820595 CEAM3_HUMAN (1-146): 1.53e-73: 229: 84.25		CEAM3_HUMAN (1-143): 6.06e-44: 151: 64.34
+	Hs
		445630 CEAM6_HUMAN (1-344): 3.04e-83: 257: 100.00		CEAM5_HUMAN (4-265): 3.4e-24: 103: 21.13
+	Hs
		820601 CEAM6_HUMAN (1-344): 3.04e-83: 257: 100.00		CEAM6_HUMAN (26-265): 7.93e-25: 103: 21.81
+	Hs
		731822 CEAM6_HUMAN (1-344): 3.04e-83: 257: 100.00		CEAM8_HUMAN (26-265): 1.43e-22: 96.8: 23.46
+	Hs
		731819 CEAM8_HUMAN (1-344): 8.84e-74: 233: 78.22		CEAM8_HUMAN (26-265): 1.43e-22: 96.8: 23.46
+	Hs
		543421 PSG5_HUMAN (1-322): 9.47e-73: 230: 57.72		PSG1_HUMAN (3-234): 5.84e-23: 98.8: 16.17
+	Hs
		1027931 PSG11_HUMAN (1-322): 4.34e-70: 223: 58.03		PSG4_HUMAN (4-234): 8.29e-25: 103: 17.52
+	Hs
		1027928 PSG4_HUMAN (2-319): 2.56e-46: 164: 37.62		PSG3_HUMAN (3-248): 6.35e-25: 104: 16.47
+	Hs
		1027932 PSG4_HUMAN (2-319): 2.56e-46: 164: 37.62		PSG8_HUMAN (3-236): 4.01e-24: 101: 15.61
+	Hs
		1158745 PSG3_HUMAN (2-322): 5.51e-46: 163: 37.58		PSG8_HUMAN (3-236): 4.01e-24: 101: 15.61
+	Hs
		543416 PSG4_HUMAN (2-319): 2.56e-46: 164: 37.62		PSG1_HUMAN (3-234): 5.84e-23: 98.8: 16.17
+	Hs
		1027917 PSG3_HUMAN (2-322): 5.51e-46: 163: 37.58		PSG9_HUMAN (25-261): 2.48e-23: 99: 28.57
+	Hs
		543423 PSG3_HUMAN (2-322): 5.51e-46: 163: 37.58		PSG1_HUMAN (3-234): 5.84e-23: 98.8: 16.17
+	Hs
		1027933 PSG3_HUMAN (2-322): 5.51e-46: 163: 37.58		PSG6_HUMAN (4-248): 3.34e-22: 96.8: 16.00
+	Hs
		543417 PSG6_HUMAN (2-335): 1.1e-44: 160: 35.91		PSG1_HUMAN (3-234): 5.84e-23: 98.8: 16.17