HitPredict

Interactor 1: TCPZ (P40227)
T-complex protein 1 subunit zeta (TCP-1-zeta) (EC 3.6.1.-) (Acute morphine dependence-related protein 2) (CCT-zeta-1) (Chaperonin containing T-complex polypeptide 1 subunit 6A) (HTR3) (Tcp20)
Gene: CCT6A

Interactor 2: FBW1B (Q9UKB1)
F-box/WD repeat-containing protein 11 (F-box and WD repeats protein beta-TrCP2) (F-box/WD repeat-containing protein 1B) (Homologous to Slimb protein) (HOS)
Gene: FBXW11

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	25515538
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Cpn60_TCP1~WD40
Common GO terms	GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 531 Hs			1 542
+	Hs
		1407634 TCPH_HUMAN (2-530): 0: 576: 27.93		FBW1A_HUMAN (3-542): 2.2e-160: 471: 81.73
+	Hs
		821625 TCPZ_HUMAN (1-531): 0: 573: 100.00		FBW1A_HUMAN (3-542): 2.2e-160: 471: 81.73
+	Hs
		845257 TCPG_HUMAN (3-528): 0: 559: 27.96		LIS1_HUMAN (155-431): 2.01e-71: 235: 22.15
+	Hs
		821491 TCPZ_HUMAN (1-531): 0: 573: 100.00		FBXW7_HUMAN (342-536): 4.72e-52: 190: 30.00
+	Hs
		1291941 TCPH_HUMAN (2-530): 0: 576: 27.93		WDR5B_HUMAN (347-541): 2.01e-49: 175: 29.41
+	Hs
		821436 TCPZ_HUMAN (1-531): 0: 573: 100.00		WDR5B_HUMAN (347-541): 2.01e-49: 175: 29.41
+	Hs
		1407594 TCPH_HUMAN (2-530): 0: 576: 27.93		NLE1_HUMAN (348-541): 1.24e-45: 169: 24.16
+	Hs
		1287302 TCPH_HUMAN (2-530): 0: 576: 27.93		WDR86_HUMAN (29-348): 3.14e-46: 167: 14.15
+	Hs
		821597 TCPZ_HUMAN (1-531): 0: 573: 100.00		NLE1_HUMAN (348-541): 1.24e-45: 169: 24.16
+	Hs
		821431 TCPZ_HUMAN (1-531): 0: 573: 100.00		WDR86_HUMAN (29-348): 3.14e-46: 167: 14.15
+	Hs
		882014 TCPG_HUMAN (3-528): 0: 559: 27.96		WDR5B_HUMAN (347-541): 2.01e-49: 175: 29.41
+	Hs
		882009 TCPG_HUMAN (3-528): 0: 559: 27.96		WDR86_HUMAN (29-348): 3.14e-46: 167: 14.15
+	Hs
		965190 TCPH_HUMAN (2-530): 0: 576: 27.93		WDR5_HUMAN (395-542): 1.72e-37: 142: 24.03
+	Hs
		821289 TCPZ_HUMAN (1-531): 0: 573: 100.00		WDR5_HUMAN (395-542): 1.72e-37: 142: 24.03
+	Sc
		811114 TCPZ_YEAST (3-530): 0: 579: 56.75		MDV1_YEAST (357-532): 8.16e-30: 126: 19.07
+	Hs
		881861 TCPG_HUMAN (3-528): 0: 559: 27.96		WDR5_HUMAN (395-542): 1.72e-37: 142: 24.03
+	Sc
		793922 TCPZ_YEAST (3-530): 0: 579: 56.75		TAF5_YEAST (240-478): 1.44e-24: 110: 29.26
+	Hs
		209325 TCPH_HUMAN (2-530): 0: 576: 27.93		PRP4_HUMAN (430-534): 1.01e-09: 63: 14.53
+	Hs
		209209 TCPZ_HUMAN (1-531): 0: 573: 100.00		PRP4_HUMAN (430-534): 1.01e-09: 63: 14.53
+	Hs
		209218 TCPG_HUMAN (3-528): 0: 559: 27.96		PRP4_HUMAN (430-534): 1.01e-09: 63: 14.53