HitPredict

Interactor 1: VHL (P40337)
von Hippel-Lindau disease tumor suppressor (Protein G7) (pVHL)
Gene: VHL

Interactor 2: NS1BP (Q9Y6Y0)
Influenza virus NS1A-binding protein (NS1-BP) (NS1-binding protein) (Aryl hydrocarbon receptor-associated protein 3) (Kelch-like protein 39)
Gene: IVNS1ABP

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	21942715
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005654 - nucleoplasm GO:0005829 - cytosol GO:0043161 - proteasome-mediated ubiquitin-dependent protein catabolic process GO:1990756 - ubiquitin-like ligase-substrate adaptor activity
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 213 Hs			1 642
+	Hs
		822698 VHL_HUMAN (1-213): 3.46e-146: 407: 100.00		KLH12_HUMAN (1-607): 3.66e-154: 458: 24.71
+	Hs
		822877 VHL_HUMAN (1-213): 3.46e-146: 407: 100.00		KLHL1_HUMAN (144-641): 5.36e-67: 235: 21.71
+	Hs
		822722 VHL_HUMAN (1-213): 3.46e-146: 407: 100.00		KLH17_HUMAN (404-639): 1.09e-62: 221: 36.02
+	Hs
		822717 VHL_HUMAN (1-213): 3.46e-146: 407: 100.00		KLH10_HUMAN (417-641): 2.93e-59: 211: 36.84
+	Hs
		822762 VHL_HUMAN (1-213): 3.46e-146: 407: 100.00		KLH23_HUMAN (514-641): 5.9e-25: 111: 28.24
+	Hs
		822746 VHL_HUMAN (1-213): 3.46e-146: 407: 100.00		KLHL7_HUMAN (464-633): 1.1e-11: 69.7: 24.43