HitPredict

Interactor 1: AGRE5 (P48960)
Adhesion G protein-coupled receptor E5 (Leukocyte antigen CD97) (CD antigen CD97) [Cleaved into: Adhesion G protein-coupled receptor E5 subunit alpha; Adhesion G protein-coupled receptor E5 subunit beta]
Gene: ADGRE5

Interactor 2: CUL3 (Q13618)
Cullin-3 (CUL-3)
Gene: CUL3

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	35563538
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane GO:0006954 - inflammatory response GO:0016020 - membrane GO:0070062 - extracellular exosome
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 835 Hs			1 768
+	Hs
		315827 AGRL2_HUMAN (315-835): 7.7e-125: 410: 31.60		CUL4A_HUMAN (10-768): 0: 791: 38.32
+	Hs
		146756 AGRB1_HUMAN (26-800): 3.25e-79: 282: 17.50		CUL4A_HUMAN (10-768): 0: 791: 38.32
+	Hs
		1042356 NELL2_HUMAN (99-241): 1.02e-19: 96.7: 33.57		CUL3_HUMAN (1-768): 0: 951: 100.00
+	Hs
		1042020 LTBP4_HUMAN (120-266): 1.39e-14: 80.5: 35.81		CUL3_HUMAN (1-768): 0: 951: 100.00
+	Hs
		724369 FBN2_HUMAN (22-246): 4.23e-10: 65.9: 26.54		CUL3_HUMAN (1-768): 0: 951: 100.00
+	Hs
		1042342 HMCN1_HUMAN (60-178): 9.49e-10: 64.7: 32.79		CUL3_HUMAN (1-768): 0: 951: 100.00
+	Hs
		724339 FBN1_HUMAN (32-241): 5.83e-09: 62.4: 26.62		CUL3_HUMAN (1-768): 0: 951: 100.00