Protein: ATAD2
ATPase histone chaperone YTA7 (EC 3.6.1.-) (ATPase family AAA domain-containing protein YTA7) (AAA-ATPase) (Tat-binding homolog 7)

Gene: ATAD2, YTA7
Organism: Saccharomyces cerevisiae S288C
Interactions: 195
UniProt ID: P40340

Gene Ontology (top 5):
GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0000775 - chromosome, centromeric region
GO:0000785 - chromatin
GO:0003682 - chromatin binding
GO:0005524 - ATP binding

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

743097

STH1
Nuclear protein STH1/NPS1

4

8

Small-scale

0.867

High

823053

RSC58
Chromatin structure-remodeling complex protein RSC58

4

0

Small-scale

0.823

High

823021

RSC4
Chromatin structure-remodeling complex subunit RSC4

3

14

High-throughput

0.817

High

823046

RSC2
Chromatin structure-remodeling complex subunit RSC2

3

13

High-throughput

0.817

High

800995

RFC1
Replication factor C subunit 1

2

8

High-throughput

0.754

High

679755

CDC48
Cell division control protein 48

2

18

High-throughput

0.737

High

822984

ATAD2
ATPase histone chaperone YTA7

2

17

High-throughput

0.737

High

823015

ORC1
Origin recognition complex subunit 1

2

7

High-throughput

0.737

High

823017

H3
Histone H3

6

14

Small-scale

0.719

High

739656

SPT16
FACT complex subunit SPT16

6

6

Small-scale

0.719

High

646426

RAD53
Serine/threonine-protein kinase RAD53

4

4

Small-scale

0.686

High

381531

H2B2
Histone H2B.2

4

10

High-throughput

0.672

High

382137

H4
Histone H4

4

6

High-throughput

0.672

High

419758

H2A2
Histone H2A.2

4

4

High-throughput

0.672

High

757764

SAS3
Histone acetyltransferase SAS3

4

1

Small-scale

0.672

High

823035

POB3
FACT complex subunit POB3

4

1

Small-scale

0.672

High

823043

PDP3
NuA3 HAT complex component PDP3

4

1

Small-scale

0.672

High

823050

RSC3
Chromatin structure-remodeling complex protein RSC3

4

2

Small-scale

0.672

High

678324

RSC6
Chromatin structure-remodeling complex protein RSC6

4

0

Small-scale

0.643

High

448973

TOP2
DNA topoisomerase 2

3

2

Small-scale

0.640

High

381124

H2B1
Histone H2B.1

3

10

High-throughput

0.633

High

744307

CHD1
Chromo domain-containing protein 1

3

5

High-throughput

0.633

High

794185

ISW1
ISWI chromatin-remodeling complex ATPase ISW1

3

7

High-throughput

0.633

High

823025

HOS3
Histone deacetylase HOS3

3

9

High-throughput

0.633

High

823039

ARP9
Actin-like protein ARP9

3

8

High-throughput

0.633

High

823061

NTO1
NuA3 HAT complex component NTO1

3

3

High-throughput

0.633

High

823067

CMR1
DNA damage-binding protein CMR1

3

11

High-throughput

0.633

High

823069

H2AZ
Histone H2A.Z

3

6

High-throughput

0.633

High

364571

CDK1
Cyclin-dependent kinase 1

2

4

Small-scale

0.629

High

777057

BDF1
Bromodomain-containing factor 1

1

14

High-throughput

0.618

High

800951

RFC3
Replication factor C subunit 3

1

6

High-throughput

0.618

High

822985

RFC2
Replication factor C subunit 2

1

6

High-throughput

0.618

High

823052

BDF2
Bromodomain-containing factor 2

1

6

High-throughput

0.618

High

745589

RSC7
Chromatin structure-remodeling complex subunit RSC7

3

0

High-throughput

0.606

High

820418

RT106
Histone chaperone RTT106

3

0

Small-scale

0.606

High

823026

RSC9
Chromatin structure-remodeling complex subunit RSC9

3

0

High-throughput

0.606

High

823057

IOC2
ISWI one complex protein 2

3

0

High-throughput

0.606

High

419439

H2A1
Histone H2A.1

2

4

Small-scale

0.594

High

807765

CSK2C
Casein kinase II subunit beta'

3

4

Small-scale

0.587

High

402022

RPB1
DNA-directed RNA polymerase II subunit RPB1

2

7

Small-scale

0.584

High

470536

RPB2
DNA-directed RNA polymerase II subunit RPB2

2

6

Small-scale

0.584

High

594401

RPB3
DNA-directed RNA polymerase II subunit RPB3

2

4

Small-scale

0.584

High

794078

MCM7
DNA replication licensing factor MCM7

2

5

Small-scale

0.584

High

822987

DSN1
Kinetochore-associated protein DSN1

2

1

High-throughput

0.584

High

822992

RSC8
Chromatin structure-remodeling complex protein RSC8

2

2

Small-scale

0.584

High

822994

CSK2B
Casein kinase II subunit beta

3

4

Small-scale

0.578

High

823016

ORC4
Origin recognition complex subunit 4

1

1

High-throughput

0.575

High

823027

GCN5
Histone acetyltransferase GCN5

1

13

High-throughput

0.575

High

622962

CSK22
Casein kinase II subunit alpha'

2

9

Small-scale

0.571

High

664438

MCM3
DNA replication licensing factor MCM3

2

6

High-throughput

0.571

High

712994

MCM2
DNA replication licensing factor MCM2

2

6

High-throughput

0.571

High

713269

MCM5
Minichromosome maintenance protein 5

2

4

High-throughput

0.571

High

734429

BTAF1
TATA-binding protein-associated factor MOT1

2

12

High-throughput

0.571

High

802633

YHI0
Putative proline--tRNA ligase YHR020W

2

7

High-throughput

0.571

High

807083

FKBP3
Peptidyl-prolyl cis-trans isomerase

2

11

High-throughput

0.571

High

823002

TAF6
SAGA complex/transcription factor TFIID complex subunit TAF6

2

1

High-throughput

0.571

High

823011

H1
Histone H1

2

1

High-throughput

0.571

High

823029

RUVB1
RuvB-like protein 1

2

7

High-throughput

0.571

High

823044

FKBP4
FK506-binding protein 4

2

10

High-throughput

0.571

High

823065

RUVB2
RuvB-like protein 2

2

7

High-throughput

0.571

High

149213

FOB1
DNA replication fork-blocking protein FOB1

2

0

High-throughput

0.547

High

823032

IOC4
ISWI one complex protein 4

2

0

High-throughput

0.547

High

823042

SFH1
Chromatin structure-remodeling complex subunit SFH1

2

0

High-throughput

0.547

High

823003

APC10
Anaphase-promoting complex subunit DOC1

1

2

High-throughput

0.541

High

545087

SSB1
Ribosome-associated molecular chaperone SSB1

1

13

High-throughput

0.536

High

822998

NET1
Nucleolar protein NET1

2

2

High-throughput

0.521

High

823012

COPA
Coatomer subunit alpha

2

8

High-throughput

0.521

High

823022

TOF2
Topoisomerase 1-associated factor 2

2

2

High-throughput

0.521

High

746492

BEM3
GTPase-activating protein BEM3

1

1

High-throughput

0.489

High

597154

BIP
Endoplasmic reticulum chaperone BiP

1

8

High-throughput

0.481

High

700108

PRP45
Pre-mRNA-processing protein 45

1

2

Small-scale

0.481

High

744121

BRR2
Pre-mRNA-splicing helicase BRR2

1

4

Small-scale

0.481

High

822990

GZF3
Protein GZF3

1

1

High-throughput

0.481

High

823049

HDA2
HDA1 complex subunit 2

1

1

High-throughput

0.481

High

359250

G3P3
Glyceraldehyde-3-phosphate dehydrogenase 3

1

4

High-throughput

0.479

High

402219

RPC1
DNA-directed RNA polymerase III subunit RPC1

1

7

High-throughput

0.479

High

415227

TOP1
DNA topoisomerase 1

1

2

High-throughput

0.479

High

444540

DED1
ATP-dependent RNA helicase DED1

1

6

High-throughput

0.479

High

448313

PDE2
3',5'-cyclic-nucleotide phosphodiesterase 2

1

1

High-throughput

0.479

High

459100

RPAC1
DNA-directed RNA polymerases I and III subunit RPAC1

1

4

High-throughput

0.479

High

534269

RPA1
DNA-directed RNA polymerase I subunit RPA190

1

7

High-throughput

0.479

High

585951

CSK21
Casein kinase II subunit alpha

1

10

Small-scale

0.479

High

632169

RPAB1
DNA-directed RNA polymerases I, II, and III subunit RPABC1

1

1

Small-scale

0.479

High

639023

VPS1
Vacuolar protein sorting-associated protein 1

1

8

High-throughput

0.479

High

641433

RCC1
Guanine nucleotide exchange factor SRM1

1

3

High-throughput

0.479

High

644935

RPA2
DNA-directed RNA polymerase I subunit RPA135

1

6

High-throughput

0.479

High

647129

RPC2
DNA-directed RNA polymerase III subunit RPC2

1

6

High-throughput

0.479

High

647777

RFA1
Replication factor A protein 1

1

4

High-throughput

0.479

High

707262

TF2B
Transcription initiation factor IIB

1

5

High-throughput

0.479

High

709795

BMH1
Protein BMH1

1

11

High-throughput

0.479

High

721378

MCM4
DNA replication licensing factor MCM4

1

6

High-throughput

0.479

High

734113

EF2
Elongation factor 2

1

7

High-throughput

0.479

High

735007

RPC3
DNA-directed RNA polymerase III subunit RPC3

1

2

High-throughput

0.479

High

745764

GSP1
GTP-binding nuclear protein GSP1/CNR1

1

10

High-throughput

0.479

High

746632

DRS1
ATP-dependent RNA helicase DRS1

1

12

High-throughput

0.479

High

750089

MRT4
Ribosome assembly factor MRT4

1

6

High-throughput

0.479

High

779249

CENPA
Histone H3-like centromeric protein CSE4

1

14

Small-scale

0.479

High

792080

GBLP
Small ribosomal subunit protein RACK1

1

8

High-throughput

0.479

High

803986

RSC30
Chromatin structure-remodeling complex protein RSC30

1

2

High-throughput

0.479

High

822999

SMC3
Structural maintenance of chromosomes protein 3

1

3

Small-scale

0.479

High

823006

PRP43
Pre-mRNA-splicing factor ATP-dependent RNA helicase PRP43

1

2

High-throughput

0.479

High

823007

NSA1
Ribosome biogenesis protein NSA1

1

2

High-throughput

0.479

High

823008

PBP1
PAB1-binding protein 1

1

1

High-throughput

0.479

High

823014

APJ1
J domain-containing protein APJ1

1

9

High-throughput

0.479

High

823019

ACAC
Acetyl-CoA carboxylase

1

10

High-throughput

0.479

High

823020

RPA49
DNA-directed RNA polymerase I subunit RPA49

1

1

High-throughput

0.479

High

823023

ULP1
Ubiquitin-like-specific protease 1

1

2

High-throughput

0.479

High

823030

HMO1
High mobility group protein 1

1

4

High-throughput

0.479

High

823031

SCC2
Sister chromatid cohesion protein 2

1

1

High-throughput

0.479

High

823034

DPB4
DNA polymerase epsilon subunit D

1

1

Small-scale

0.479

High

823036

ERB1
Ribosome biogenesis protein ERB1

1

6

High-throughput

0.479

High

823040

SWR1
Helicase SWR1

1

6

High-throughput

0.479

High

823041

MMS22
E3 ubiquitin-protein ligase substrate receptor MMS22

1

1

High-throughput

0.479

High

823047

RRP15
Ribosomal RNA-processing protein 15

1

1

High-throughput

0.479

High

823054

SGO1
Shugoshin

1

2

High-throughput

0.479

High

823056

YTM1
Ribosome biogenesis protein YTM1

1

14

High-throughput

0.479

High

823058

YRA1
RNA annealing protein YRA1

1

7

High-throughput

0.479

High

823059

PSH1
RING finger protein PSH1

1

4

High-throughput

0.479

High

823060

MAK21
Ribosome biogenesis protein MAK21

1

4

High-throughput

0.479

High

823062

HAT1
Histone acetyltransferase type B catalytic subunit

1

1

High-throughput

0.479

High

823063

ARP7
Actin-related protein 7

1

6

High-throughput

0.479

High

823064

NOP56
Nucleolar protein 56

1

5

High-throughput

0.479

High

823068

IF6
Eukaryotic translation initiation factor 6

1

1

High-throughput

0.479

High

823070

SMC6
Structural maintenance of chromosomes protein 6

1

6

High-throughput

0.479

High

749680

TYE7
Transcription factor TYE7

1

0

High-throughput

0.460

High

822997

TAF1
Transcription initiation factor TFIID subunit 1

1

0

High-throughput

0.460

High

823048

NDE1
Nuclear distribution protein nudE homolog 1

1

0

High-throughput

0.460

High

645059

RPAB5
DNA-directed RNA polymerases I, II, and III subunit RPABC5

1

0

Small-scale

0.458

High

763906

SPT10
Protein SPT10

1

0

High-throughput

0.458

High

796025

LDB7
Chromatin structure-remodeling complex protein RSC14

1

0

High-throughput

0.458

High

805598

LSM12
Protein LSM12

1

0

High-throughput

0.458

High

806928

RPB11
DNA-directed RNA polymerase II subunit RPB11

1

0

High-throughput

0.458

High

822991

IOC3
ISWI one complex protein 3

1

0

High-throughput

0.458

High

822995

RPA43
DNA-directed RNA polymerase I subunit RPA43

1

0

High-throughput

0.458

High

823009

RT102
Regulator of Ty1 transposition protein 102

1

0

High-throughput

0.458

High

823071

HTL1
High temperature lethal protein 1

1

0

High-throughput

0.458

High

392824

HSP82
ATP-dependent molecular chaperone HSP82

1

10

High-throughput

0.445

High

448177

HAP2
Transcriptional activator HAP2

1

1

High-throughput

0.445

High

504602

YL12B
Transposon Ty1-LR2 Gag-Pol polyprotein

1

3

High-throughput

0.445

High

524127

HSP71
Heat shock protein SSA1

1

13

High-throughput

0.445

High

526842

HSP72
Heat shock protein SSA2

1

13

High-throughput

0.445

High

554003

TCPA
T-complex protein 1 subunit alpha

1

12

High-throughput

0.445

High

579501

HSC82
ATP-dependent molecular chaperone HSC82

1

10

High-throughput

0.445

High

590641

HSP26
Heat shock protein 26

1

2

High-throughput

0.445

High

676047

MAS5
Mitochondrial protein import protein MAS5

1

9

High-throughput

0.445

High

694560

SPT5
Transcription elongation factor SPT5

1

3

High-throughput

0.445

High

705772

IDH1
Isocitrate dehydrogenase [NAD] subunit 1, mitochondrial

1

8

High-throughput

0.445

High

724879

RAD16
DNA repair protein RAD16

1

8

High-throughput

0.445

High

737674

HIR2
Protein HIR2

1

7

High-throughput

0.445

High

741690

HSP7F
Heat shock protein homolog SSE1

1

20

High-throughput

0.445

High

763447

MDJ1
DnaJ homolog 1, mitochondrial

1

10

High-throughput

0.445

High

793934

TAF5
SAGA complex/transcription factor TFIID complex subunit TAF5

1

15

High-throughput

0.445

High

800711

RCK1
Serine/threonine-protein kinase RCK1

1

5

High-throughput

0.445

High

802086

IMDH2
Inosine-5'-monophosphate dehydrogenase 2

1

1

High-throughput

0.445

High

815017

SNF7
Vacuolar-sorting protein SNF7

1

7

High-throughput

0.445

High

816229

HSP7E
Heat shock protein SSC3, mitochondrial

1

10

High-throughput

0.445

High

817869

IMB4
Importin subunit beta-4

1

8

High-throughput

0.445

High

818906

SSB2
Ribosome-associated molecular chaperone SSB2

1

13

High-throughput

0.445

High

823000

TCPQ
T-complex protein 1 subunit theta

1

12

High-throughput

0.445

High

823001

PFD6
Prefoldin subunit 6

1

1

High-throughput

0.445

High

823004

INO80
Chromatin-remodeling ATPase INO80

1

9

High-throughput

0.445

High

823028

TAF12
SAGA complex/transcription factor TFIID complex subunit TAF12

1

3

High-throughput

0.445

High

823037

RCO1
Transcriptional regulatory protein RCO1

1

4

High-throughput

0.445

High

823051

SWA2
Auxilin-like clathrin uncoating factor SWA2

1

5

High-throughput

0.445

High

823055

ISW2
ISWI chromatin-remodeling complex ATPase ISW2

1

9

High-throughput

0.445

High

823066

CAF1A
Chromatin assembly factor 1 subunit A

1

3

High-throughput

0.445

High

470650

ERG20
Farnesyl pyrophosphate synthase

1

2

Small-scale

0.439

High

736985

CDC3
Cell division control protein 3

1

6

High-throughput

0.439

High

758099

CASP
Protein CASP

1

7

High-throughput

0.439

High

823045

SP382
Pre-mRNA-splicing factor SPP382

1

0

High-throughput

0.438

High

740723

SRP40
Suppressor protein SRP40

1

3

High-throughput

0.437

High

803871

CIC1
Proteasome-interacting protein CIC1

1

2

High-throughput

0.437

High

822986

MAM33
Mitochondrial acidic protein MAM33

1

3

High-throughput

0.437

High

823024

UTP17
NET1-associated nuclear protein 1

1

5

High-throughput

0.437

High

626511

AP1
AP-1-like transcription factor YAP1

1

0

High-throughput

0.426

High

649971

SIN3
Transcriptional regulatory protein SIN3

1

0

High-throughput

0.426

High

738156

NGG1
SAGA complex subunit NGG1

1

0

High-throughput

0.426

High

763742

CENPC
Inner kinetochore subunit MIF2

1

0

High-throughput

0.426

High

781749

SET3
SET domain-containing protein 3

1

0

High-throughput

0.426

High

822996

SUM1
Suppressor of mar1-1 protein

1

0

High-throughput

0.426

High

823005

ITC1
Imitation switch two complex protein 1

1

0

High-throughput

0.426

High

823010

RRN9
RNA polymerase I-specific transcription initiation factor RRN9

1

0

High-throughput

0.426

High

732154

COPG
Coatomer subunit gamma

1

7

High-throughput

0.407

High

803979

YHL4
Uncharacterized protein YHR054C

1

1

High-throughput

0.407

High

821012

EIF3I
Eukaryotic translation initiation factor 3 subunit I

1

9

High-throughput

0.407

High

822988

COPB2
Coatomer subunit beta'

1

7

High-throughput

0.407

High

822989

MPG1
Mannose-1-phosphate guanyltransferase

1

3

High-throughput

0.407

High

822993

ERJ5
ER-localized J domain-containing protein 5

1

7

High-throughput

0.407

High

823018

DID2
Vacuolar protein-sorting-associated protein 46

1

2

High-throughput

0.407

High

823033

PFD5
Prefoldin subunit 5

1

2

High-throughput

0.407

High

823038

SNO4
Probable glutathione-independent glyoxalase SNO4

1

1

High-throughput

0.407

High

823013

SNZ2
Probable pyridoxal 5'-phosphate synthase subunit SNZ2

2

0

High-throughput

0.298

High

672419

STE50
Protein STE50

1

0

High-throughput

0.251

Low

818105

SHO1
High osmolarity signaling protein SHO1

1

0

Small-scale

0.251

Low


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Last updated: 11Aug2025