Interactor 1: TRPC1 (P48995)
Short transient receptor potential channel 1 (TrpC1) (Transient receptor protein 1) (TRP-1)
Gene: TRPC1

Interactor 2: TRPC4 (Q9UBN4)
Short transient receptor potential channel 4 (TrpC4) (Trp-related protein 4) (hTrp-4) (hTrp4)
Gene: TRPC4

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.64 1.00 0.806

The method score is based on:

Property Details
Experiments 12857742, 12032305
Identification Methods affinity chromatography technology, fluorescent resonance energy transfer
Interaction Type physical association, direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains Ion_trans~Ion_trans, Ank_2~TRP_2
Common GO terms GO:0005262 - calcium channel activity
GO:0005886 - plasma membrane
GO:0006816 - calcium ion transport
GO:0015279 - store-operated calcium channel activity
GO:0034703 - cation channel complex
and 3 others

more...

Homologous interactions 15

Homologous interactions

Color coding for hit scores

1 793
Hs

1 977
+ Mm
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Mm
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+ Dm
+ Hs
+ Hs
+ Hs
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+ Rn
+ Hs

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Last updated: 15 Jul 2024