Interactor 1: LMAN1 (P49257)
Protein ERGIC-53 (ER-Golgi intermediate compartment 53 kDa protein) (Gp58) (Intracellular mannose-specific lectin MR60) (Lectin mannose-binding 1)
Gene: LMAN1

Interactor 2: MCFD2 (Q8NI22)
Multiple coagulation factor deficiency protein 2 (Neural stem cell-derived neuronal survival protein)
Gene: MCFD2

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.94 0.90 0.922

The method score is based on:

Property Details
Experiments 12717434, 33961781, 35271311, 20142513, 17971482, 19787799, 16304051, 20138881
Identification Methods affinity chromatography technology, cosedimentation in solution, nuclear magnetic resonance, mass spectrometry studies of complexes, molecular sieving, isothermal titration calorimetry, x-ray crystallography, anti bait coimmunoprecipitation, anti tag coimmunoprecipitation
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains EF-hand_7~Lectin_leg-like
Common GO terms GO:0005789 - endoplasmic reticulum membrane
GO:0012507 - ER to Golgi transport vesicle membrane
GO:0015031 - protein transport
GO:0033116 - endoplasmic reticulum-Golgi intermediate compartment membrane
Homologous interactions 0

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Last updated: 15 Jul 2024