HitPredict

Interactor 1: STAT3 (P40763)
Signal transducer and activator of transcription 3 (Acute-phase response factor)
Gene: STAT3

Interactor 2: BICD1 (Q96G01)
Protein bicaudal D homolog 1 (Bic-D 1)
Gene: BICD1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.66	0.60	0.631

Property	Details
Experiments	28718761, 21988832
Identification Methods	proximity labelling technology, affinity chromatography technology, two hybrid, pull down
Interaction Type	physical association, direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0019901 - protein kinase binding
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1 770 Hs			1 975
+	Hs
		827856 STAT3_HUMAN (1-770): 0: 1048: 100.00		BICD2_HUMAN (6-812): 7.25e-59: 219: 62.93
+	Hs
		838142 STAT1_HUMAN (1-749): 0: 929: 51.52		BICD2_HUMAN (6-812): 7.25e-59: 219: 62.93
+	Hs
		270781 STAT3_HUMAN (1-770): 0: 1048: 100.00		ROCK2_HUMAN (43-768): 1.27e-13: 77.6: 15.15
+	Hs
		1132025 STAT4_HUMAN (1-729): 0: 893: 48.44		BICD2_HUMAN (6-812): 7.25e-59: 219: 62.93
+	Hs
		838245 STAT6_HUMAN (1-753): 0: 627: 24.10		BICD2_HUMAN (6-812): 7.25e-59: 219: 62.93