Protein: STAT4
Signal transducer and activator of transcription 4

Gene: STAT4
Organism: Homo sapiens
Interactions: 44
UniProt ID: Q14765

Gene Ontology (top 5):
GO:0000785 - chromatin
GO:0000978 - RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0003700 - DNA-binding transcription factor activity
GO:0005634 - nucleus

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

838097

STAT1
Signal transducer and activator of transcription 1-alpha/beta

3

17

Small-scale

0.847

High

1132029

I12R2
Interleukin-12 receptor subunit beta-2

2

6

Small-scale

0.806

High

1132021

IRF4
Interferon regulatory factor 4

2

20

Small-scale

0.789

High

164860

SH21B
SH2 domain-containing protein 1B

2

18

High-throughput

0.767

High

855625

CRK
Adapter molecule crk

2

4

High-throughput

0.767

High

1132020

STAT4
Signal transducer and activator of transcription 4

1

16

Small-scale

0.692

High

827785

STAT3
Signal transducer and activator of transcription 3

1

17

Small-scale

0.618

High

378432

IFNG
Interferon gamma

2

3

Small-scale

0.584

High

533935

IRF1
Interferon regulatory factor 1

2

20

Small-scale

0.584

High

458399

ADRB2
Beta-2 adrenergic receptor

1

2

Small-scale

0.552

High

913722

ZN136
Zinc finger protein 136

1

1

High-throughput

0.536

High

167270

KLF11
Krueppel-like factor 11

1

5

High-throughput

0.515

High

161468

KMT2D
Histone-lysine N-methyltransferase 2D

1

2

High-throughput

0.479

High

297811

PIAS2
E3 SUMO-protein ligase PIAS2

1

5

Small-scale

0.479

High

338328

SC24A
Protein transport protein Sec24A

1

2

High-throughput

0.479

High

338472

SC24B
Protein transport protein Sec24B

1

2

High-throughput

0.479

High

429901

JUN
Transcription factor Jun

1

12

Small-scale

0.479

High

488477

UCHL1
Ubiquitin carboxyl-terminal hydrolase isozyme L1

1

1

Small-scale

0.479

High

575827

IL2RB
Interleukin-2 receptor subunit beta

1

20

Small-scale

0.479

High

789113

NUP62
Nuclear pore glycoprotein p62

1

1

High-throughput

0.479

High

1024038

TFAM
Transcription factor A, mitochondrial

1

2

High-throughput

0.479

High

1092538

ECH1
Delta(3,5)-Delta(2,4)-dienoyl-CoA isomerase, mitochondrial

1

2

High-throughput

0.479

High

1099899

TIF1B
Transcription intermediary factor 1-beta

1

11

Small-scale

0.479

High

1101211

NMI
N-myc-interactor

1

6

Small-scale

0.479

High

1112288

PWP1
Periodic tryptophan protein 1 homolog

1

7

High-throughput

0.479

High

1132022

SC23B
Protein transport protein Sec23B

1

2

High-throughput

0.479

High

1132024

ALMS1
Centrosome-associated protein ALMS1

1

1

High-throughput

0.479

High

1132025

BICD2
Protein bicaudal D homolog 2

1

5

Small-scale

0.479

High

1132028

PDLI2
PDZ and LIM domain protein 2

1

2

Small-scale

0.479

High

1132030

PCGF1
Polycomb group RING finger protein 1

1

3

High-throughput

0.479

High

1132035

TBX21
T-box transcription factor TBX21

1

6

Small-scale

0.479

High

175048

SC16A
Protein transport protein Sec16A

1

0

High-throughput

0.458

High

219173

LTOR5
Ragulator complex protein LAMTOR5

1

0

Small-scale

0.458

High

1132023

BCL7A
B-cell CLL/lymphoma 7 protein family member A

1

0

High-throughput

0.458

High

1132026

DI3L1
DIS3-like exonuclease 1

1

0

High-throughput

0.458

High

1132027

SMG7
Nonsense-mediated mRNA decay factor SMG7

1

0

High-throughput

0.458

High

1132032

PDIP3
Polymerase delta-interacting protein 3

1

0

High-throughput

0.458

High

299196

FLOT1
Flotillin-1

1

5

High-throughput

0.457

High

1124805

FLOT2
Flotillin-2

1

5

High-throughput

0.457

High

378625

IL2RA
Interleukin-2 receptor subunit alpha

1

2

Small-scale

0.437

High

1132034

IL21
Interleukin-21

1

3

Small-scale

0.437

High

1132031

NUP58
Nucleoporin p58/p45

1

0

High-throughput

0.268

Low

1132033

WDCP
WD repeat and coiled-coil-containing protein

1

0

High-throughput

0.249

Low


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Last updated: 11Aug2025