HitPredict

Interactor 1: RAC1 (P40792)
Ras-related protein Rac1
Gene: RAC1

Interactor 2: DIAP1 (Q24306)
Death-associated inhibitor of apoptosis 1 (EC 2.3.2.27) (Apoptosis 1 inhibitor) (E3 ubiquitin-protein ligase th) (Inhibitor of apoptosis 1) (Protein thread) (RING-type E3 ubiquitin transferase Diap1)
Gene: DIAP1

Species: Drosophila melanogaster

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	15242648
Identification Methods	pull down
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0007298 - border follicle cell migration GO:1903688 - positive regulation of border follicle cell migration
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 192 Dm			1 438
+	Mm
		988890 RAC1_MOUSE (1-192): 7.26e-85: 250: 91.67		XIAP_MOUSE (2-156): 5.91e-39: 148: 22.01
+	Hs
		988276 RAC1_HUMAN (1-192): 7.26e-85: 250: 91.67		XIAP_HUMAN (2-156): 4.74e-38: 146: 21.25
+	Hs
		580989 RAC2_HUMAN (1-192): 3.07e-81: 241: 89.06		XIAP_HUMAN (2-156): 4.74e-38: 146: 21.25
+	Hs
		953391 RAC3_HUMAN (1-191): 4.3e-78: 233: 89.53		XIAP_HUMAN (2-156): 4.74e-38: 146: 21.25
+	Hs
		955057 CDC42_HUMAN (1-192): 2.46e-78: 233: 69.27		XIAP_HUMAN (2-156): 4.74e-38: 146: 21.25
+	Hs
		988341 RAC1_HUMAN (1-192): 7.26e-85: 250: 91.67		BIRC3_HUMAN (213-401): 2.68e-20: 95.4: 21.08
+	Hs
		988342 RAC1_HUMAN (1-192): 7.26e-85: 250: 91.67		BIRC2_HUMAN (181-401): 6.93e-20: 94.3: 16.96
+	Hs
		955134 CDC42_HUMAN (1-192): 2.46e-78: 233: 69.27		BIRC3_HUMAN (213-401): 2.68e-20: 95.4: 21.08
+	Hs
		955135 CDC42_HUMAN (1-192): 2.46e-78: 233: 69.27		BIRC2_HUMAN (181-401): 6.93e-20: 94.3: 16.96
+	Hs
		962021 RHOA_HUMAN (5-192): 1.2e-76: 229: 54.79		BIRC3_HUMAN (213-401): 2.68e-20: 95.4: 21.08
+	Hs
		962022 RHOA_HUMAN (5-192): 1.2e-76: 229: 54.79		BIRC2_HUMAN (181-401): 6.93e-20: 94.3: 16.96