HitPredict

Interactor 1: RAC1 (P40792)
Ras-related protein Rac1
Gene: RAC1

Interactor 2: Q9V428 (Q9V428)
Ras suppressor protein 1
Gene: ics

Species: Drosophila melanogaster

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.80	0.553

Property	Details
Experiments	26170296
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	LRR_8~Ras
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 192 Dm			1 283
+	Hs
		988609 RAC1_HUMAN (1-192): 7.26e-85: 250: 91.67		LRCH3_HUMAN (29-259): 1.2e-52: 184: 28.57
+	Hs
		955475 CDC42_HUMAN (1-192): 2.46e-78: 233: 69.27		LRCH3_HUMAN (29-259): 1.2e-52: 184: 28.57
+	Hs
		988630 RAC1_HUMAN (1-192): 7.26e-85: 250: 91.67		ERBIN_HUMAN (1-233): 7.28e-44: 160: 24.71
+	Dm
		828001 RAC1_DROME (1-192): 1.62e-82: 244: 100.00		SCRIB_DROME (40-281): 1.25e-43: 160: 22.13
+	Hs
		581243 RAC2_HUMAN (1-192): 3.07e-81: 241: 89.06		ERBIN_HUMAN (1-233): 7.28e-44: 160: 24.71
+	Hs
		955280 CDC42_HUMAN (1-192): 2.46e-78: 233: 69.27		LRCH2_HUMAN (7-252): 1.99e-46: 167: 26.22
+	Hs
		1401933 RHOJ_HUMAN (2-190): 4.29e-80: 239: 60.32		ERBIN_HUMAN (1-233): 7.28e-44: 160: 24.71
+	Hs
		1015697 RHOG_HUMAN (1-192): 3.53e-78: 233: 67.19		ERBIN_HUMAN (1-233): 7.28e-44: 160: 24.71
+	Hs
		955500 CDC42_HUMAN (1-192): 2.46e-78: 233: 69.27		ERBIN_HUMAN (1-233): 7.28e-44: 160: 24.71
+	Hs
		988360 RAC1_HUMAN (1-192): 7.26e-85: 250: 91.67		SCRIB_HUMAN (107-281): 5.44e-21: 94.7: 19.89
+	Hs
		581041 RAC2_HUMAN (1-192): 3.07e-81: 241: 89.06		SCRIB_HUMAN (107-281): 5.44e-21: 94.7: 19.89
+	Hs
		1122344 RHOJ_HUMAN (2-190): 4.29e-80: 239: 60.32		SCRIB_HUMAN (107-281): 5.44e-21: 94.7: 19.89
+	Hs
		1015432 RHOG_HUMAN (1-192): 3.53e-78: 233: 67.19		SCRIB_HUMAN (107-281): 5.44e-21: 94.7: 19.89
+	Hs
		955158 CDC42_HUMAN (1-192): 2.46e-78: 233: 69.27		SCRIB_HUMAN (107-281): 5.44e-21: 94.7: 19.89
+	Hs
		988509 RAC1_HUMAN (1-192): 7.26e-85: 250: 91.67		LRC8A_HUMAN (51-258): 2.06e-14: 75.2: 17.94
+	Hs
		581157 RAC2_HUMAN (1-192): 3.07e-81: 241: 89.06		LRC8A_HUMAN (51-258): 2.06e-14: 75.2: 17.94
+	Hs
		988387 RAC1_HUMAN (1-192): 7.26e-85: 250: 91.67		RSU1_HUMAN (10-95): 2.17e-11: 64.7: 22.09
+	Hs
		1310840 RHOJ_HUMAN (2-190): 4.29e-80: 239: 60.32		LRC8A_HUMAN (51-258): 2.06e-14: 75.2: 17.94
+	Hs
		1015583 RHOG_HUMAN (1-192): 3.53e-78: 233: 67.19		LRC8A_HUMAN (51-258): 2.06e-14: 75.2: 17.94
+	Hs
		955358 CDC42_HUMAN (1-192): 2.46e-78: 233: 69.27		LRC8A_HUMAN (51-258): 2.06e-14: 75.2: 17.94