HitPredict

Interactor 1: CDC42 (P40793)
Cdc42 homolog (EC 3.6.5.2)
Gene: CDC42

Interactor 2: Q9Y0S9 (Q9Y0S9)
Abelson interacting protein, isoform A (Abelson interacting protein, isoform B) (Abelson interacting protein, isoform F) (Abl tyrosine kinase-interacting protein) (LD37010p)
Gene: Abi

Species: Drosophila melanogaster

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	19716703
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0008360 - regulation of cell shape GO:0030027 - lamellipodium GO:0030031 - cell projection assembly GO:0030036 - actin cytoskeleton organization GO:0030866 - cortical actin cytoskeleton organization and 1 others more... GO:0048477 - oogenesis
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 191 Dm			1 473
+	Hs
		988517 RAC1_HUMAN (1-191): 6.47e-83: 245: 69.63		ABI1_HUMAN (13-473): 8.96e-88: 279: 33.65
+	Hs
		988763 RAC1_HUMAN (1-191): 6.47e-83: 245: 69.63		ABI2_HUMAN (13-473): 3.24e-82: 265: 35.95
+	Hs
		1015847 RHOG_HUMAN (1-191): 1.25e-80: 239: 60.21		ABI2_HUMAN (13-473): 3.24e-82: 265: 35.95
+	Hs
		955674 CDC42_HUMAN (1-191): 3.82e-80: 238: 92.67		ABI2_HUMAN (13-473): 3.24e-82: 265: 35.95
+	Hs
		65907 RAC1_HUMAN (1-191): 6.47e-83: 245: 69.63		RHG42_HUMAN (3-469): 2.62e-40: 156: 13.47
+	Hs
		601261 RHOQ_HUMAN (4-187): 1.26e-92: 270: 69.57		MYO1E_HUMAN (270-472): 7.38e-31: 128: 19.46
+	Hs
		1211652 RHOJ_HUMAN (2-188): 8.88e-84: 248: 63.64		FBP1L_HUMAN (32-469): 4.55e-34: 136: 12.53
+	Hs
		988427 RAC1_HUMAN (1-191): 6.47e-83: 245: 69.63		FBP1L_HUMAN (32-469): 4.55e-34: 136: 12.53
+	Hs
		626454 RAC1_HUMAN (1-191): 6.47e-83: 245: 69.63		NCF2_HUMAN (61-472): 1.65e-33: 134: 10.76
+	Hs
		1091716 RHOJ_HUMAN (2-188): 8.88e-84: 248: 63.64		MYO1E_HUMAN (270-472): 7.38e-31: 128: 19.46
+	Hs
		955266 CDC42_HUMAN (1-191): 3.82e-80: 238: 92.67		FBP1L_HUMAN (32-469): 4.55e-34: 136: 12.53
+	Hs
		988326 RAC1_HUMAN (1-191): 6.47e-83: 245: 69.63		MYO1E_HUMAN (270-472): 7.38e-31: 128: 19.46
+	Hs
		988817 RAC1_HUMAN (1-191): 6.47e-83: 245: 69.63		ASAP1_HUMAN (118-469): 8.54e-31: 128: 16.06
+	Hs
		626452 CDC42_HUMAN (1-191): 3.82e-80: 238: 92.67		NCF2_HUMAN (61-472): 1.65e-33: 134: 10.76
+	Hs
		1015398 RHOG_HUMAN (1-191): 1.25e-80: 239: 60.21		MYO1E_HUMAN (270-472): 7.38e-31: 128: 19.46
+	Dm
		828044 RAC1_DROME (1-191): 1.06e-80: 239: 69.79		RHGF_DROME (119-470): 7.35e-31: 128: 13.72
+	Hs
		955107 CDC42_HUMAN (1-191): 3.82e-80: 238: 92.67		MYO1E_HUMAN (270-472): 7.38e-31: 128: 19.46
+	Hs
		49959 CDC42_HUMAN (1-191): 3.82e-80: 238: 92.67		RHG10_HUMAN (281-470): 4.23e-26: 114: 18.10
+	Hs
		955207 CDC42_HUMAN (1-191): 3.82e-80: 238: 92.67		ITSN1_HUMAN (4-472): 2.86e-12: 71.4: 9.36
+	Hs
		955258 CDC42_HUMAN (1-191): 3.82e-80: 238: 92.67		SH319_HUMAN (417-472): 1.98e-10: 65.1: 35.71