Interactor 1: SYSC (P49591)
Serine--tRNA ligase, cytoplasmic (EC 6.1.1.11) (Seryl-tRNA synthetase) (SerRS) (Seryl-tRNA(Ser/Sec) synthetase)
Gene: SARS1

Interactor 2: SIR2 (Q8IXJ6)
NAD-dependent protein deacetylase sirtuin-2 (EC 2.3.1.286) (NAD-dependent protein defatty-acylase sirtuin-2) (EC 2.3.1.-) (Regulatory protein SIR2 homolog 2) (SIR2-like protein 2)
Gene: SIRT2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.80 0.60 0.697

The method score is based on:

Property Details
Experiments 26186194, 28514442, 17353931, 33961781
Identification Methods affinity chromatography technology, anti bait coimmunoprecipitation, anti tag coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0005634 - nucleus
GO:0005737 - cytoplasm
GO:0005739 - mitochondrion
GO:0005829 - cytosol
Homologous interactions 3

Homologous interactions

Color coding for hit scores

1 514
Hs

1 389
+ Sc
+ Sc
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024