HitPredict

Interactor 1: P2C56 (P49597)
Protein phosphatase 2C 56 (AtPP2C56) (EC 3.1.3.16) (Protein ABSCISIC ACID-INSENSITIVE 1) (Protein phosphatase 2C ABI1) (PP2C ABI1)
Gene: ABI1

Interactor 2: PYL1 (Q8VZS8)
Abscisic acid receptor PYL1 (ABI1-binding protein 6) (PYR1-like protein 1) (Regulatory components of ABA receptor 9)
Gene: PYL1

Species: Arabidopsis thaliana

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.95	1.00	0.976

Property	Details
Experiments	19893533, 19855379, 20729862, 32612234, 19874541, 19898420, unassigned2354
Identification Methods	x-ray crystallography, pull down, two hybrid, affinity chromatography technology, amplified luminescent proximity homogeneous assay, molecular sieving, two hybrid array, two hybrid prey pooling approach, validated two hybrid
Interaction Type	association, direct interaction, physical association

Property	Details
Interacting Pfam domains	PP2C~Polyketide_cyc2
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0005886 - plasma membrane GO:0009738 - abscisic acid-activated signaling pathway
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 434 At			1 221
+	At
		221991 P2C56_ARATH (1-434): 7.17e-178: 505: 100.00		PYR1_ARATH (28-220): 2.06e-98: 285: 76.68
+	At
		829507 P2C56_ARATH (1-434): 7.17e-178: 505: 100.00		PYL6_ARATH (5-210): 6.54e-94: 275: 44.44
+	At
		829503 P2C56_ARATH (1-434): 7.17e-178: 505: 100.00		PYL9_ARATH (42-214): 4.5e-94: 274: 46.24
+	At
		829492 P2C56_ARATH (1-434): 7.17e-178: 505: 100.00		PYL7_ARATH (41-216): 1.98e-92: 271: 46.59
+	At
		829523 P2C56_ARATH (1-434): 7.17e-178: 505: 100.00		PYL5_ARATH (9-207): 1.37e-91: 268: 44.44
+	At
		829518 P2C56_ARATH (1-434): 7.17e-178: 505: 100.00		PYL8_ARATH (39-216): 9.1e-89: 261: 44.94
+	At
		829504 P2C56_ARATH (1-434): 7.17e-178: 505: 100.00		PYL10_ARATH (34-212): 9.8e-85: 250: 41.90
+	At
		286072 P2C56_ARATH (1-434): 7.17e-178: 505: 100.00		PYL2_ARATH (29-212): 6.76e-84: 249: 49.46
+	At
		829543 P2C56_ARATH (1-434): 7.17e-178: 505: 100.00		PYL3_ARATH (29-207): 2.07e-83: 248: 48.65
+	At
		285957 P2C56_ARATH (1-434): 7.17e-178: 505: 100.00		PYL4_ARATH (34-212): 1.33e-77: 233: 51.93
+	At
		138639 P2C77_ARATH (1-434): 3.59e-146: 424: 71.37		PYL1_ARATH (1-221): 6.84e-100: 290: 100.00
+	At
		138616 P2C77_ARATH (1-434): 3.59e-146: 424: 71.37		PYR1_ARATH (28-220): 2.06e-98: 285: 76.68
+	At
		829520 P2C56_ARATH (1-434): 7.17e-178: 505: 100.00		PYL12_ARATH (55-208): 1.2e-63: 196: 51.30
+	At
		829521 P2C56_ARATH (1-434): 7.17e-178: 505: 100.00		PYL11_ARATH (55-209): 1.21e-63: 196: 53.55
+	At
		138637 P2C77_ARATH (1-434): 3.59e-146: 424: 71.37		PYL6_ARATH (5-210): 6.54e-94: 275: 44.44
+	At
		138635 P2C77_ARATH (1-434): 3.59e-146: 424: 71.37		PYL9_ARATH (42-214): 4.5e-94: 274: 46.24
+	At
		829542 P2C56_ARATH (1-434): 7.17e-178: 505: 100.00		PYL13_ARATH (56-210): 1.41e-56: 178: 47.50
+	At
		138636 P2C77_ARATH (1-434): 3.59e-146: 424: 71.37		PYL10_ARATH (34-212): 9.8e-85: 250: 41.90
+	At
		138619 P2C77_ARATH (1-434): 3.59e-146: 424: 71.37		PYL2_ARATH (29-212): 6.76e-84: 249: 49.46
+	At
		138618 P2C77_ARATH (1-434): 3.59e-146: 424: 71.37		PYL4_ARATH (34-212): 1.33e-77: 233: 51.93