Protein: RT4I1
NAD(P)H oxidoreductase RTN4IP1, mitochondrial (EC 1.6.5.-) (NOGO-interacting mitochondrial protein) (Reticulon-4-interacting protein 1)

Gene: RT4I1, RTN4IP1
Organism: Homo sapiens
Interactions: 89
UniProt ID: Q8WWV3

Gene Ontology (top 5):
GO:0005739 - mitochondrion
GO:0005741 - mitochondrial outer membrane
GO:0005759 - mitochondrial matrix
GO:0006744 - ubiquinone biosynthetic process
GO:0007399 - nervous system development

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1241151

LTMD1
LETM1 domain-containing protein 1

4

2

High-throughput

0.691

High

1156164

ZYX
Zyxin

6

1

High-throughput

0.666

High

916187

BIEA
Biliverdin reductase A

3

0

High-throughput

0.638

High

1359787

FXRD1
FAD-dependent oxidoreductase domain-containing protein 1

2

1

High-throughput

0.628

High

1359794

PYM1
Partner of Y14 and mago

4

1

High-throughput

0.626

High

325008

HEXI1
Protein HEXIM1

3

1

High-throughput

0.609

High

1055250

MTG8
Protein CBFA2T1

2

1

High-throughput

0.606

High

716705

ATPD
ATP synthase F(1) complex subunit delta, mitochondrial

2

0

High-throughput

0.602

High

1341181

PPTC7
Protein phosphatase PTC7 homolog

2

0

High-throughput

0.602

High

1087467

GRSF1
G-rich sequence factor 1

2

5

High-throughput

0.584

High

1162449

CLPP
ATP-dependent Clp protease proteolytic subunit, mitochondrial

2

1

High-throughput

0.584

High

1359810

ARFG3
ADP-ribosylation factor GTPase-activating protein 3

2

0

High-throughput

0.580

High

1359813

MARH5
E3 ubiquitin-protein ligase MARCHF5

2

0

High-throughput

0.580

High

279845

CISY
Citrate synthase, mitochondrial

2

0

High-throughput

0.559

High

1359799

SRBS1
Sorbin and SH3 domain-containing protein 1

2

1

High-throughput

0.553

High

1359803

WWTR1
WW domain-containing transcription regulator protein 1

2

7

High-throughput

0.553

High

1359809

SMUF2
E3 ubiquitin-protein ligase SMURF2

2

7

High-throughput

0.553

High

1359817

GGA2
ADP-ribosylation factor-binding protein GGA2

2

1

High-throughput

0.553

High

869204

UCRI
Cytochrome b-c1 complex subunit Rieske, mitochondrial

1

0

High-throughput

0.513

High

1235922

PDE12
2',5'-phosphodiesterase 12

1

0

High-throughput

0.513

High

1328243

RM50
Large ribosomal subunit protein mL50

1

0

High-throughput

0.513

High

289162

PRDM1
PR domain zinc finger protein 1

1

0

Small-scale

0.493

High

1248162

SAS6
Spindle assembly abnormal protein 6 homolog

1

1

High-throughput

0.489

High

1322765

CNTRB
Centrobin

1

1

High-throughput

0.489

High

1359814

PLK2
Serine/threonine-protein kinase PLK2

1

1

High-throughput

0.489

High

270263

MTG16
Protein CBFA2T3

1

1

High-throughput

0.481

High

1095729

CACO2
Calcium-binding and coiled-coil domain-containing protein 2

1

4

High-throughput

0.481

High

282023

MPPB
Mitochondrial-processing peptidase subunit beta

1

1

High-throughput

0.479

High

287339

RF1M
Peptide chain release factor 1, mitochondrial

1

3

High-throughput

0.479

High

471153

ODPA
Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial

1

4

High-throughput

0.479

High

532816

CH60
60 kDa heat shock protein, mitochondrial

1

2

High-throughput

0.479

High

786189

LONM
Lon protease homolog, mitochondrial

1

7

High-throughput

0.479

High

828867

MDHM
Malate dehydrogenase, mitochondrial

1

1

High-throughput

0.479

High

841845

LPPRC
Leucine-rich PPR motif-containing protein, mitochondrial

1

1

High-throughput

0.479

High

856319

IF2M
Translation initiation factor IF-2, mitochondrial

1

3

High-throughput

0.479

High

1024115

TFAM
Transcription factor A, mitochondrial

1

1

High-throughput

0.479

High

1083685

MPPA
Mitochondrial-processing peptidase subunit alpha

1

1

High-throughput

0.479

High

1090477

TRAP1
Heat shock protein 75 kDa, mitochondrial

1

14

High-throughput

0.479

High

1117790

AUHM
Methylglutaconyl-CoA hydratase, mitochondrial

1

3

High-throughput

0.479

High

1254829

TRI67
Tripartite motif-containing protein 67

1

11

High-throughput

0.479

High

1272945

FAKD5
FAST kinase domain-containing protein 5, mitochondrial

1

1

High-throughput

0.479

High

1337201

MCU
Calcium uniporter protein, mitochondrial

1

1

High-throughput

0.479

High

1359784

FAKD4
FAST kinase domain-containing protein 4

1

1

High-throughput

0.479

High

1359785

MCUR1
Mitochondrial calcium uniporter regulator 1

1

1

High-throughput

0.479

High

1359790

DNJA3
DnaJ homolog subfamily A member 3, mitochondrial

1

2

High-throughput

0.479

High

1359792

EFGM
Elongation factor G, mitochondrial

1

2

High-throughput

0.479

High

1359796

TACO1
Translational activator of cytochrome c oxidase 1

1

1

High-throughput

0.479

High

1359800

HINT2
Adenosine 5'-monophosphoramidase HINT2

1

1

High-throughput

0.479

High

1359802

CC90B
Coiled-coil domain-containing protein 90B, mitochondrial

1

1

High-throughput

0.479

High

1359804

MTRFR
Mitochondrial translation release factor in rescue

1

3

High-throughput

0.479

High

1359806

MET17
Ribosome assembly protein METTL17, mitochondrial

1

1

High-throughput

0.479

High

1359808

ACAD9
Complex I assembly factor ACAD9, mitochondrial

1

1

High-throughput

0.479

High

1359812

MCUB
Calcium uniporter regulatory subunit MCUb, mitochondrial

1

1

High-throughput

0.479

High

1359816

RF1ML
Peptide chain release factor 1-like, mitochondrial

1

3

High-throughput

0.479

High

1359786

Q96CP1
RELA protein

1

3

High-throughput

0.470

High

61563

VWA8
von Willebrand factor A domain-containing protein 8

1

0

High-throughput

0.458

High

66249

MET15
12S rRNA N(4)-cytidine methyltransferase METTL15

1

0

High-throughput

0.458

High

183691

RT12
Small ribosomal subunit protein uS12m

1

0

High-throughput

0.458

High

275075

COQ9
Ubiquinone biosynthesis protein COQ9, mitochondrial

1

0

High-throughput

0.458

High

350935

TRUB2
Pseudouridylate synthase TRUB2, mitochondrial

1

0

High-throughput

0.458

High

519178

COX8A
Cytochrome c oxidase subunit 8A, mitochondrial

1

0

High-throughput

0.458

High

851968

EFTS
Elongation factor Ts, mitochondrial

1

0

High-throughput

0.458

High

1048612

SSBP
Single-stranded DNA-binding protein, mitochondrial

1

0

High-throughput

0.458

High

1058170

C1QBP
Complement component 1 Q subcomponent-binding protein, mitochondrial

1

0

High-throughput

0.458

High

1142609

PDK1
[Pyruvate dehydrogenase

1

0

High-throughput

0.458

High

1207083

SYAM
Alanine--tRNA ligase, mitochondrial

1

0

High-throughput

0.458

High

1234466

MRM1
rRNA methyltransferase 1, mitochondrial

1

0

High-throughput

0.458

High

1359788

RRFM
Ribosome-recycling factor, mitochondrial

1

0

High-throughput

0.458

High

1359789

MTEF3
Transcription termination factor 3, mitochondrial

1

0

High-throughput

0.458

High

1359791

TEFM
Transcription elongation factor, mitochondrial

1

0

High-throughput

0.458

High

1359793

IMP2L
Mitochondrial inner membrane protease subunit 2

1

0

High-throughput

0.458

High

1359797

TMM70
Transmembrane protein 70, mitochondrial

1

0

High-throughput

0.458

High

1359798

TR61B
tRNA

1

0

High-throughput

0.458

High

1359801

NMES1
Normal mucosa of esophagus-specific gene 1 protein

1

0

High-throughput

0.458

High

1359815

MRES1
Mitochondrial transcription rescue factor 1

1

0

High-throughput

0.458

High

1359820

RM11
Large ribosomal subunit protein uL11m

1

0

High-throughput

0.458

High

1045574

TF65
Transcription factor p65

1

3

High-throughput

0.439

High

1015635

RHOG
Rho-related GTP-binding protein RhoG

1

3

High-throughput

0.437

High

1323736

S39AB
Zinc transporter ZIP11

1

1

High-throughput

0.407

High

1359805

BORG4
Cdc42 effector protein 4

3

0

High-throughput

0.347

High

1006277

CTG1B
Cancer/testis antigen 1

2

0

High-throughput

0.316

High

1091782

PP1R8
Nuclear inhibitor of protein phosphatase 1

2

0

High-throughput

0.316

High

1275998

HDX
Highly divergent homeobox

2

0

High-throughput

0.316

High

1347327

ERMIN
Ermin

2

0

High-throughput

0.316

High

1359795

CENPK
Centromere protein K

2

0

High-throughput

0.316

High

1359807

SFR19
Splicing factor, arginine/serine-rich 19

2

0

High-throughput

0.316

High

1359818

EXOC7
Exocyst complex component 7

1

0

High-throughput

0.282

High

1359819

WBP11
WW domain-binding protein 11

1

0

High-throughput

0.282

High

1359811

RTN4
Reticulon-4

1

0

Small-scale

0.249

Low


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Last updated: 11Aug2025