Protein: PTGR3
Prostaglandin reductase 3 (PRG-3) (EC 1.3.1.48) (Zinc-binding alcohol dehydrogenase domain-containing protein 2)

Gene: PTGR3
Organism: Homo sapiens
Interactions: 36
UniProt ID: Q8N4Q0

Gene Ontology (top 5):
GO:0005739 - mitochondrion
GO:0005777 - peroxisome
GO:0006629 - lipid metabolic process
GO:0008270 - zinc ion binding
GO:0045599 - negative regulation of fat cell differentiation

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

539367

ODB2
Lipoamide acyltransferase component of branched-chain alpha-keto acid dehydrogenase complex, mitochondrial

3

4

High-throughput

0.662

High

1065005

FGL1
Fibrinogen-like protein 1

4

1

High-throughput

0.630

High

1162422

CLPP
ATP-dependent Clp protease proteolytic subunit, mitochondrial

2

1

High-throughput

0.584

High

573862

CCNB1
G2/mitotic-specific cyclin-B1

2

1

High-throughput

0.574

High

1326710

MD1L1
Mitotic spindle assembly checkpoint protein MAD1

2

3

High-throughput

0.574

High

896270

PEX5
Peroxisomal targeting signal 1 receptor

2

0

Small-scale

0.559

High

1150450

NHRF2
Na(+)/H(+) exchange regulatory cofactor NHE-RF2

2

1

High-throughput

0.549

High

1061343

CP24A
1,25-dihydroxyvitamin D(3) 24-hydroxylase, mitochondrial

1

2

High-throughput

0.536

High

1275796

RM21
Large ribosomal subunit protein bL21m

1

0

High-throughput

0.513

High

1326701

LNX1
E3 ubiquitin-protein ligase LNX

1

2

Small-scale

0.501

High

1287268

DPP9
Dipeptidyl peptidase 9

1

1

High-throughput

0.489

High

879269

NR2C2
Nuclear receptor subfamily 2 group C member 2

1

3

High-throughput

0.479

High

1092589

ECH1
Delta(3,5)-Delta(2,4)-dienoyl-CoA isomerase, mitochondrial

1

3

High-throughput

0.479

High

1254630

TRI67
Tripartite motif-containing protein 67

1

12

High-throughput

0.479

High

399996

CATA
Catalase

1

0

High-throughput

0.458

High

422578

A4
Amyloid-beta precursor protein

1

4

High-throughput

0.457

High

1326703

NED4L
E3 ubiquitin-protein ligase NEDD4-like

1

6

High-throughput

0.457

High

791531

SYUA
Alpha-synuclein

1

1

High-throughput

0.445

High

1244558

SYDM
Aspartate--tRNA ligase, mitochondrial

1

3

High-throughput

0.445

High

106264

APRIO
Alternative prion protein

1

4

High-throughput

0.437

High

768639

RFA3
Replication protein A 14 kDa subunit

1

4

High-throughput

0.437

High

958150

ARP3
Actin-related protein 3

1

1

High-throughput

0.437

High

1326707

PKHA4
Pleckstrin homology domain-containing family A member 4

1

2

High-throughput

0.437

High

1326708

HECD1
E3 ubiquitin-protein ligase HECTD1

1

6

Small-scale

0.437

High

1135663

NAA25
N-alpha-acetyltransferase 25, NatB auxiliary subunit

1

1

High-throughput

0.407

High

874051

TPC10
Trafficking protein particle complex subunit 10

3

0

High-throughput

0.345

High

1326702

TPC14
Trafficking protein particle complex subunit 14

3

0

High-throughput

0.345

High

1326706

RBSK
Ribokinase

2

0

High-throughput

0.318

High

1307829

TPPC5
Trafficking protein particle complex subunit 5

2

0

High-throughput

0.313

High

1326704

TPPC9
Trafficking protein particle complex subunit 9

2

0

High-throughput

0.313

High

1326709

TPPC4
Trafficking protein particle complex subunit 4

2

0

High-throughput

0.313

High

753925

CKS2
Cyclin-dependent kinases regulatory subunit 2

1

0

High-throughput

0.279

Low

1326699

JMY
Junction-mediating and -regulatory protein

1

0

High-throughput

0.279

Low

1326705

ATGA1
Autophagy-related protein 101

1

0

High-throughput

0.279

Low

1037556

RL18A
Large ribosomal subunit protein eL20

1

0

High-throughput

0.232

Low

1326700

RCBT1
RCC1 and BTB domain-containing protein 1

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025