HitPredict

Interactor 1: KC1E (P49674)
Casein kinase I isoform epsilon (CKI-epsilon) (CKIe) (EC 2.7.11.1)
Gene: CSNK1E

Interactor 2: SAV1 (Q9H4B6)
Protein salvador homolog 1 (45 kDa WW domain protein) (hWW45)
Gene: SAV1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	0.60	0.628

Property	Details
Experiments	24255178, 23455922
Identification Methods	affinity chromatography technology, tandem affinity purification, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0005829 - cytosol
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 416 Hs			1 383
+	Hs
		822372 KC1D_HUMAN (1-406): 2e-125: 370: 83.25		SAV1_HUMAN (1-383): 9.28e-111: 330: 100.00
+	Hs
		822382 KC1D_HUMAN (1-406): 2e-125: 370: 83.25		SMUF1_HUMAN (147-381): 2.43e-59: 206: 18.32
+	Hs
		830415 KC1E_HUMAN (1-416): 1.42e-136: 399: 100.00		KIBRA_HUMAN (197-355): 2.75e-30: 124: 20.47
+	Hs
		1039182 KCC2D_HUMAN (4-339): 1.58e-119: 358: 16.62		WWOX_HUMAN (198-282): 3.98e-30: 121: 31.87
+	Hs
		808043 KC1D_HUMAN (1-406): 2e-125: 370: 83.25		NEDD4_HUMAN (42-307): 3.99e-20: 94.4: 14.84
+	Hs
		808324 AKT3_HUMAN (2-355): 3.23e-119: 357: 18.31		NEDD4_HUMAN (42-307): 3.99e-20: 94.4: 14.84
+	Hs
		681731 AKT1_HUMAN (5-356): 7.92e-119: 356: 18.56		NEDD4_HUMAN (42-307): 3.99e-20: 94.4: 14.84
+	Hs
		1299664 AKT3_HUMAN (2-355): 3.23e-119: 357: 18.31		NED4L_HUMAN (151-312): 1.2e-09: 62.1: 18.07
+	Hs
		681988 AKT1_HUMAN (5-356): 7.92e-119: 356: 18.56		NED4L_HUMAN (151-312): 1.2e-09: 62.1: 18.07