HitPredict

Interactor 1: CCNF (P41002)
Cyclin-F (F-box only protein 1)
Gene: CCNF

Interactor 2: NOTC2 (Q04721)
Neurogenic locus notch homolog protein 2 (Notch 2) (hN2) [Cleaved into: Notch 2 extracellular truncation (N2ECD); Notch 2 intracellular domain (N2ICD)]
Gene: NOTCH2

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.56	1.00	0.754

Property	Details
Experiments	33729478, 36114006
Identification Methods	proximity labelling technology, affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Ank_2~F-box-like
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm
Homologous interactions	4

Homologous interactions

Color coding for hit scores

	1 786 Hs			1 2471
+	Hs
		830645 CCNF_HUMAN (1-786): 0: 952: 100.00		ANK3_HUMAN (1732-2286): 1.32e-110: 399: 15.11
+	Hs
		830583 CCNF_HUMAN (1-786): 0: 952: 100.00		ANK2_HUMAN (1719-2317): 5.19e-108: 390: 14.51
+	Hs
		274110 CCNF_HUMAN (1-786): 0: 952: 100.00		ANR17_HUMAN (1801-2469): 2.56e-69: 262: 17.34
+	Hs
		831031 CCNF_HUMAN (1-786): 0: 952: 100.00		ANKH1_HUMAN (1561-1903): 7.52e-30: 133: 10.28