Interactor 1: IF2G (P41091)
Eukaryotic translation initiation factor 2 subunit 3 (EC 3.6.5.3) (Eukaryotic translation initiation factor 2 subunit gamma X) (eIF2-gamma X) (eIF2gX)
Gene: EIF2S3
Interactor 2: U5S1 (Q15029)
116 kDa U5 small nuclear ribonucleoprotein component (Elongation factor Tu GTP-binding domain-containing protein 2) (SNU114 homolog) (hSNU114) (U5 snRNP-specific protein, 116 kDa) (U5-116 kDa)
Gene: EFTUD2
Species: Homo sapiens
Source: biogrid
Category: High-throughput
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.38 | 1.00 | 0.618 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 28515276 |
| Identification Methods | affinity chromatography technology |
| Interaction Type | physical association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | GTP_EFTU~eIF2_C, GTP_EFTU_D2~eIF2_C, EFG_C~GTP_EFTU, EFG_III~GTP_EFTU, EFG_IV~GTP_EFTU, EFTUD2~GTP_EFTU, GTP_EFTU~GTP_EFTU, GTP_EFTU~GTP_EFTU_D2, EFG_III~GTP_EFTU_D2, EFTUD2~GTP_EFTU_D2, GTP_EFTU_D2~GTP_EFTU_D2 |
| Common GO terms | GO:0003924 - GTPase activity GO:0005525 - GTP binding GO:0005829 - cytosol |
| Homologous interactions | 9 |
Homologous interactions
Color coding for hit scores 
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Last updated: 11Aug2025