HitPredict

Interactor 1: NU153 (P49790)
Nuclear pore complex protein Nup153 (153 kDa nucleoporin) (Nucleoporin Nup153)
Gene: NUP153

Interactor 2: UBC9 (P63279)
SUMO-conjugating enzyme UBC9 (EC 2.3.2.-) (RING-type E3 SUMO transferase UBC9) (SUMO-protein ligase) (Ubiquitin carrier protein 9) (Ubiquitin carrier protein I) (Ubiquitin-conjugating enzyme E2 I) (Ubiquitin-protein ligase I) (p18)
Gene: UBE2I

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	26496610
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005635 - nuclear envelope GO:0005643 - nuclear pore GO:0005654 - nucleoplasm GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1475 Hs			1 158
+	Hs
		834714 RBP2_HUMAN (573-1152): 6.9e-53: 207: 19.12		UBC9_HUMAN (1-158): 1.43e-70: 211: 100.00
+	Hs
		1290106 RNF31_HUMAN (545-922): 9.86e-47: 185: 15.72		UB2D4_HUMAN (4-157): 3.74e-75: 222: 34.42
+	Hs
		849403 RNF31_HUMAN (545-922): 9.86e-47: 185: 15.72		UB2D1_HUMAN (4-157): 7.96e-75: 221: 33.12
+	Hs
		919819 RNF31_HUMAN (545-922): 9.86e-47: 185: 15.72		UB2D2_HUMAN (4-157): 2.44e-74: 220: 35.07
+	Hs
		895873 RNF31_HUMAN (545-922): 9.86e-47: 185: 15.72		UB2D3_HUMAN (4-157): 6.67e-73: 216: 35.07
+	Hs
		1290028 RNF31_HUMAN (545-922): 9.86e-47: 185: 15.72		UB2E2_HUMAN (3-156): 7.29e-69: 208: 33.77
+	Hs
		1282324 RNF31_HUMAN (545-922): 9.86e-47: 185: 15.72		UB2E3_HUMAN (3-156): 2.14e-68: 207: 33.77
+	Hs
		851865 RNF31_HUMAN (545-922): 9.86e-47: 185: 15.72		UB2E1_HUMAN (3-156): 7.23e-67: 203: 33.12
+	Mm
		895978 RNF31_MOUSE (545-922): 6.44e-39: 160: 14.92		UB2D3_MOUSE (4-157): 6.67e-73: 216: 35.07
+	Hs
		483424 RGPD2_HUMAN (1136-1440): 1.34e-37: 157: 16.07		UBC9_HUMAN (1-158): 1.43e-70: 211: 100.00
+	Hs
		930320 TITIN_HUMAN (92-940): 3.34e-30: 133: 9.98		UBC9_HUMAN (1-158): 1.43e-70: 211: 100.00
+	Hs
		727237 NU214_HUMAN (146-1306): 4.07e-29: 129: 11.13		UBC9_HUMAN (1-158): 1.43e-70: 211: 100.00
+	Hs
		829039 TITIN_HUMAN (92-940): 3.34e-30: 133: 9.98		UBE2A_HUMAN (1-154): 3.37e-67: 202: 41.56
+	Hs
		919893 ZRAN1_HUMAN (589-796): 5.46e-22: 105: 16.89		UB2D2_HUMAN (4-157): 2.44e-74: 220: 35.07
+	Hs
		930435 ZRAN1_HUMAN (589-796): 5.46e-22: 105: 16.89		UBC9_HUMAN (1-158): 1.43e-70: 211: 100.00
+	Dm
		1181434 TRBID_DROME (654-921): 1.55e-20: 100: 16.23		Q7KNM2_DROME (1-158): 1.41e-66: 201: 85.44
+	Sc
		691645 NUP2_YEAST (923-1394): 5.12e-24: 111: 17.83		UBC9_YEAST (1-156): 3.53e-61: 187: 56.41
+	Dm
		973539 CPN_DROME (300-1089): 2.55e-15: 83.7: 7.46		Q9VQ00_DROME (2-157): 1.56e-66: 201: 35.90
+	Hs
		857961 NUP98_HUMAN (749-1368): 8.75e-11: 69.1: 12.83		UBC9_HUMAN (1-158): 1.43e-70: 211: 100.00
+	Sc
		691654 NUP2_YEAST (923-1394): 5.12e-24: 111: 17.83		UBC7_YEAST (1-149): 9.95e-31: 110: 38.13