Interactor 1: GSK3B (P49841)
Glycogen synthase kinase-3 beta (GSK-3 beta) (EC 2.7.11.26) (Serine/threonine-protein kinase GSK3B) (EC 2.7.11.1)
Gene: GSK3B

Interactor 2: FBW1A (Q9Y297)
F-box/WD repeat-containing protein 1A (E3RSIkappaB) (Epididymis tissue protein Li 2a) (F-box and WD repeats protein beta-TrCP) (pIkappaBalpha-E3 receptor subunit)
Gene: BTRC

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.67 0.60 0.634

The method score is based on:

Property Details
Experiments 24451375, 10228155
Identification Methods enzymatic study, affinity chromatography technology, pull down
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005654 - nucleoplasm
GO:0005737 - cytoplasm
GO:0005829 - cytosol
GO:0008013 - beta-catenin binding
GO:0042752 - regulation of circadian rhythm
and 1 others

more...

Homologous interactions 11

Homologous interactions

Color coding for hit scores

1 420
Hs

1 605
+ Mm
+ Hs
+ Hs
+ Hs
+ Hs
+ Dm
+ Hs
+ Hs
+ Hs
+ At
+ At

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024