HitPredict

Interactor 1: PSMD7 (P26270)
26S proteasome non-ATPase regulatory subunit 7 (26S proteasome regulatory subunit RPN8) (26S proteasome regulatory subunit S12) (Proteasome subunit p39B) (Proteasome subunit p40) (Protein Mov34)
Gene: Rpn8

Interactor 2: Q7KMQ0 (Q7KMQ0)
26S proteasome regulatory subunit 7 (Proteasome 26S subunit ATPase 2)
Gene: Rpt1

Species: Drosophila melanogaster

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	1.00	0.575

Property	Details
Experiments	38944040
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	JAB~PRS7_OB
Common GO terms	GO:0005654 - nucleoplasm GO:0005829 - cytosol GO:0005838 - proteasome regulatory particle GO:0043161 - proteasome-mediated ubiquitin-dependent protein catabolic process
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 338 Dm			1 433
+	Dm
		198024 PSMD7_DROME (1-338): 4.59e-136: 391: 100.00		PRS8_DROME (50-430): 1.96e-123: 366: 48.29
+	Dm
		684560 PSMD7_DROME (1-338): 4.59e-136: 391: 100.00		Q9V405_DROME (1-425): 2.69e-118: 352: 35.29
+	Dm
		684544 PSMD7_DROME (1-338): 4.59e-136: 391: 100.00		PRS4_DROME (1-430): 3.95e-117: 351: 38.89
+	Dm
		684574 PSMD7_DROME (1-338): 4.59e-136: 391: 100.00		Q9W414_DROME (33-429): 1.46e-116: 347: 42.75
+	Hs
		778636 PSMD7_HUMAN (4-288): 8.73e-104: 309: 81.75		PRS7_HUMAN (1-433): 1e-143: 418: 91.69
+	Hs
		906494 PSMD7_HUMAN (4-288): 8.73e-104: 309: 81.75		PRS4_HUMAN (1-430): 1.02e-120: 360: 40.28
+	Hs
		906495 PSMD7_HUMAN (4-288): 8.73e-104: 309: 81.75		PRS8_HUMAN (25-430): 3.46e-120: 357: 45.57
+	Hs
		906497 PSMD7_HUMAN (4-288): 8.73e-104: 309: 81.75		PRS10_HUMAN (34-429): 9.58e-118: 350: 41.60
+	Sc
		751017 RPN8_YEAST (9-312): 1.24e-91: 278: 46.27		PRS7_YEAST (1-433): 5.55e-128: 379: 67.24
+	Hs
		851269 PSMD7_HUMAN (4-288): 8.73e-104: 309: 81.75		PRS6B_HUMAN (17-425): 4.21e-116: 347: 36.84
+	Sp
		152924 RPN11_SCHPO (3-272): 2.42e-61: 199: 18.00		PRS6A_SCHPO (22-431): 7.01e-152: 439: 36.74
+	Sc
		1033899 RPN8_YEAST (9-312): 1.24e-91: 278: 46.27		PRS8_YEAST (41-430): 1.24e-115: 346: 45.13
+	Hs
		137990 PSDE_HUMAN (2-275): 4.39e-61: 199: 16.78		PRS7_HUMAN (1-433): 1e-143: 418: 91.69
+	Sp
		206967 RPN11_SCHPO (3-272): 2.42e-61: 199: 18.00		PRS7_SCHPO (1-430): 4.39e-131: 386: 72.58
+	Dm
		198064 PSDE_DROME (2-273): 9.69e-61: 198: 16.89		PRS8_DROME (50-430): 1.96e-123: 366: 48.29
+	Hs
		138051 PSDE_HUMAN (2-275): 4.39e-61: 199: 16.78		PRS4_HUMAN (1-430): 1.02e-120: 360: 40.28
+	Hs
		138052 PSDE_HUMAN (2-275): 4.39e-61: 199: 16.78		PRS8_HUMAN (25-430): 3.46e-120: 357: 45.57
+	Hs
		138055 PSDE_HUMAN (2-275): 4.39e-61: 199: 16.78		PRS10_HUMAN (34-429): 9.58e-118: 350: 41.60
+	Dm
		874995 PSDE_DROME (2-273): 9.69e-61: 198: 16.89		PRS4_DROME (1-430): 3.95e-117: 351: 38.89
+	Hs
		138008 PSDE_HUMAN (2-275): 4.39e-61: 199: 16.78		PRS6B_HUMAN (17-425): 4.21e-116: 347: 36.84