Interactor 1: BCL2 (P49950)
Apoptosis regulator Bcl-2
Gene: BCL2

Interactor 2: Q9JKL3 (Q9JKL3)
Bax protein splice variant k (RCG54570, isoform CRA_a)
Gene: Bax

Species: Rattus norvegicus

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.38 1.00 0.618

The method score is based on:

Property Details
Experiments 16642033
Identification Methods affinity chromatography technology
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains Bcl-2~Bcl-2, BH4~Bcl-2
Common GO terms GO:0001836 - release of cytochrome c from mitochondria
GO:0005741 - mitochondrial outer membrane
GO:0008630 - intrinsic apoptotic signaling pathway in response to DNA damage
GO:0015267 - channel activity
GO:0042803 - protein homodimerization activity
and 2 others

more...

Homologous interactions 17

Homologous interactions

Color coding for hit scores

1 236
Rn

1 173
+ Mm
+ Hs
+ Mm
+ Hs
+ Mm
+ Hs
+ Hs
+ Hs
+ Hs
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+ Hs
+ Hs
+ Hs
+ Hs
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+ Hs
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024