Interactor 1: BCL2 (P49950)
Apoptosis regulator Bcl-2
Gene: BCL2
Interactor 2: Q9JKL3 (Q9JKL3)
Bax protein splice variant k (RCG54570, isoform CRA_a)
Gene: Bax
Species: Rattus norvegicus
Source: biogrid
Category: Small-scale
Confidence: High
Method score | Annotation score | Interaction score |
---|---|---|
0.38 | 1.00 | 0.618 |
The method score is based on:
Property | Details |
---|---|
Experiments | 16642033 |
Identification Methods | affinity chromatography technology |
Interaction Type | physical association |
The annotation score is based on:
Property | Details |
---|---|
Interacting Pfam domains | Bcl-2~Bcl-2, BH4~Bcl-2 |
Common GO terms | GO:0001836 - release of cytochrome c from mitochondria GO:0005741 - mitochondrial outer membrane GO:0008630 - intrinsic apoptotic signaling pathway in response to DNA damage GO:0015267 - channel activity GO:0042803 - protein homodimerization activity and 2 others more... |
Homologous interactions | 17 |
Homologous interactions
Color coding for hit scores
Service provided by Combinatics, Japan
Last updated: 15 Jul 2024