HitPredict

Interactor 1: MTOR (P42345)
Serine/threonine-protein kinase mTOR (EC 2.7.11.1) (FK506-binding protein 12-rapamycin complex-associated protein 1) (FKBP12-rapamycin complex-associated protein) (Mammalian target of rapamycin) (mTOR) (Mechanistic target of rapamycin) (Rapamycin and FKBP12 target 1) (Rapamycin target protein 1) (Tyrosine-protein kinase mTOR) (EC 2.7.10.2)
Gene: MTOR

Interactor 2: XCT (Q9UPY5)
Cystine/glutamate transporter (Amino acid transport system xc-) (Calcium channel blocker resistance protein CCBR1) (Solute carrier family 7 member 11) (xCT)
Gene: SLC7A11

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	unassigned3795
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane GO:0016020 - membrane
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 2549 Hs			1 501
+	Hs
		1102289 ATM_HUMAN (387-2548): 0: 894: 14.98		LAT2_HUMAN (23-500): 9.87e-122: 368: 43.66
+	Hs
		1102294 ATM_HUMAN (387-2548): 0: 894: 14.98		XCT_HUMAN (1-501): 5.48e-119: 360: 100.00
+	Hs
		1010911 ATM_HUMAN (387-2548): 0: 894: 14.98		BAT1_HUMAN (23-500): 4.1e-103: 319: 43.22
+	Hs
		839514 PI4KA_HUMAN (733-2453): 4.51e-160: 552: 12.12		LAT2_HUMAN (23-500): 9.87e-122: 368: 43.66
+	Hs
		839519 PI4KA_HUMAN (733-2453): 4.51e-160: 552: 12.12		XCT_HUMAN (1-501): 5.48e-119: 360: 100.00
+	Hs
		839448 PI4KA_HUMAN (733-2453): 4.51e-160: 552: 12.12		BAT1_HUMAN (23-500): 4.1e-103: 319: 43.22
+	Hs
		1365793 GCN1_HUMAN (245-1372): 1.05e-38: 162: 12.17		XCT_HUMAN (1-501): 5.48e-119: 360: 100.00