HitPredict

Interactor 1: DYN2 (P50570)
Dynamin-2 (EC 3.6.5.5) (Dynamin 2) (Dynamin II)
Gene: DNM2

Interactor 2: BAIP2 (Q9UQB8)
BAR/IMD domain-containing adapter protein 2 (Brain-specific angiogenesis inhibitor 1-associated protein 2) (BAI-associated protein 2) (BAI1-associated protein 2) (Protein BAP2) (Fas ligand-associated factor 3) (FLAF3) (Insulin receptor substrate p53/p58) (IRS-58) (IRSp53/58) (Insulin receptor substrate protein of 53 kDa) (IRSp53) (Insulin receptor substrate p53)
Gene: BAIAP2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.44	0.60	0.515

Property	Details
Experiments	32814053
Identification Methods	two hybrid array, two hybrid pooling approach, validated two hybrid
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0005874 - microtubule GO:0005886 - plasma membrane GO:0070062 - extracellular exosome
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 870 Hs			1 552
+	Mm
		760487 DYN2_MOUSE (1-870): 0: 1057: 98.16		PACN2_MOUSE (3-436): 4.92e-64: 218: 16.29
+	Hs
		840864 DYN2_HUMAN (1-870): 0: 1057: 100.00		PACN2_HUMAN (3-436): 4.17e-62: 213: 15.61
+	Hs
		840683 DYN2_HUMAN (1-870): 0: 1057: 100.00		MYO1E_HUMAN (7-435): 3.08e-57: 208: 13.65
+	Mm
		760475 DYN2_MOUSE (1-870): 0: 1057: 98.16		PACN1_MOUSE (3-435): 2.17e-44: 165: 12.98
+	Hs
		840812 DYN2_HUMAN (1-870): 0: 1057: 100.00		PACN1_HUMAN (3-435): 1.16e-44: 165: 13.10
+	Hs
		840860 DYN2_HUMAN (1-870): 0: 1057: 100.00		PACN3_HUMAN (13-435): 1.11e-44: 165: 12.72
+	Hs
		983417 DYN1_HUMAN (1-846): 0: 1002: 79.04		PACN2_HUMAN (3-436): 4.17e-62: 213: 15.61
+	Hs
		207784 DYN2_HUMAN (1-870): 0: 1057: 100.00		PPIP1_HUMAN (33-435): 7.69e-42: 157: 16.19
+	Hs
		983372 DYN1_HUMAN (1-846): 0: 1002: 79.04		MYO1E_HUMAN (7-435): 3.08e-57: 208: 13.65
+	Hs
		840694 DYN2_HUMAN (1-870): 0: 1057: 100.00		LASP1_HUMAN (207-435): 2.59e-40: 148: 15.98
+	Mm
		760451 DYN1_MOUSE (1-844): 0: 1003: 79.23		PACN1_MOUSE (3-435): 2.17e-44: 165: 12.98
+	Hs
		983406 DYN1_HUMAN (1-846): 0: 1002: 79.04		PACN1_HUMAN (3-435): 1.16e-44: 165: 13.10
+	Hs
		983416 DYN1_HUMAN (1-846): 0: 1002: 79.04		PACN3_HUMAN (13-435): 1.11e-44: 165: 12.72
+	Hs
		983377 DYN1_HUMAN (1-846): 0: 1002: 79.04		LASP1_HUMAN (207-435): 2.59e-40: 148: 15.98
+	Hs
		840840 DYN2_HUMAN (1-870): 0: 1057: 100.00		ITSN2_HUMAN (166-444): 7.54e-12: 70.6: 14.13
+	Mm
		760485 DYN2_MOUSE (1-870): 0: 1057: 98.16		PACN3_MOUSE (82-435): 1.2e-10: 65.7: 10.90
+	Hs
		840702 DYN2_HUMAN (1-870): 0: 1057: 100.00		ITSN1_HUMAN (268-455): 5.42e-10: 64.5: 15.18
+	Mm
		760488 DYN2_MOUSE (1-870): 0: 1057: 98.16		ITSN1_MOUSE (225-455): 3.28e-09: 62.2: 13.04
+	Hs
		983379 DYN1_HUMAN (1-846): 0: 1002: 79.04		ITSN1_HUMAN (268-455): 5.42e-10: 64.5: 15.18
+	Mm
		760469 DYN1_MOUSE (1-844): 0: 1003: 79.23		ITSN1_MOUSE (225-455): 3.28e-09: 62.2: 13.04