HitPredict

Interactor 1: TCPQ (P50990)
T-complex protein 1 subunit theta (TCP-1-theta) (CCT-theta) (Chaperonin containing T-complex polypeptide 1 subunit 8) (Renal carcinoma antigen NY-REN-15)
Gene: CCT8

Interactor 2: DCAF7 (P61962)
DDB1- and CUL4-associated factor 7 (WD repeat-containing protein 68) (WD repeat-containing protein An11 homolog)
Gene: DCAF7

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.80	0.60	0.694

Property	Details
Experiments	25342745, 27705803, 33961781, 35016035
Identification Methods	affinity chromatography technology, proximity labelling technology, anti tag coimmunoprecipitation, tandem affinity purification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005654 - nucleoplasm GO:0005737 - cytoplasm GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 548 Hs			1 342
+	Hs
		903009 TCPH_HUMAN (9-538): 0: 564: 26.39		DCAF7_HUMAN (1-342): 5.45e-87: 267: 100.00
+	Hs
		826600 TCPG_HUMAN (10-547): 0: 558: 28.21		DCAF7_HUMAN (1-342): 5.45e-87: 267: 100.00
+	Ce
		954076 TCPQ_CAEEL (1-545): 0: 602: 57.66		LIN53_CAEEL (10-342): 2.97e-67: 218: 14.88
+	Hs
		134774 TCPQ_HUMAN (1-548): 0: 616: 100.00		PEX7_HUMAN (20-341): 1.26e-56: 188: 18.41
+	Hs
		843068 TCPQ_HUMAN (1-548): 0: 616: 100.00		SC31B_HUMAN (23-336): 4.36e-52: 187: 17.38
+	Hs
		1083362 TCPH_HUMAN (9-538): 0: 564: 26.39		RBBP7_HUMAN (10-342): 1.27e-68: 222: 14.51
+	Hs
		842990 TCPQ_HUMAN (1-548): 0: 616: 100.00		SNR40_HUMAN (116-342): 3.78e-43: 154: 13.66
+	Hs
		134793 TCPH_HUMAN (9-538): 0: 564: 26.39		PEX7_HUMAN (20-341): 1.26e-56: 188: 18.41
+	Hs
		1306698 TCPH_HUMAN (9-538): 0: 564: 26.39		SC31B_HUMAN (23-336): 4.36e-52: 187: 17.38
+	Hs
		134772 TCPG_HUMAN (10-547): 0: 558: 28.21		PEX7_HUMAN (20-341): 1.26e-56: 188: 18.41
+	Hs
		842958 TCPQ_HUMAN (1-548): 0: 616: 100.00		POC1A_HUMAN (2-204): 1.46e-29: 118: 18.72
+	Hs
		842812 TCPQ_HUMAN (1-548): 0: 616: 100.00		WDR5_HUMAN (208-342): 8.98e-29: 115: 11.85
+	Hs
		843019 TCPQ_HUMAN (1-548): 0: 616: 100.00		GRWD1_HUMAN (206-342): 9.29e-18: 85.5: 17.61
+	Hs
		1240450 TCPH_HUMAN (9-538): 0: 564: 26.39		POC1A_HUMAN (2-204): 1.46e-29: 118: 18.72
+	Hs
		903467 TCPH_HUMAN (9-538): 0: 564: 26.39		WDR5_HUMAN (208-342): 8.98e-29: 115: 11.85
+	Hs
		826601 TCPG_HUMAN (10-547): 0: 558: 28.21		WDR5_HUMAN (208-342): 8.98e-29: 115: 11.85
+	Hs
		1306704 TCPH_HUMAN (9-538): 0: 564: 26.39		NLE1_HUMAN (249-341): 1.44e-21: 97.2: 15.05
+	Hs
		792942 TCPG_HUMAN (10-547): 0: 558: 28.21		LIS1_HUMAN (3-151): 7.87e-23: 99.9: 14.82
+	Hs
		1306644 TCPH_HUMAN (9-538): 0: 564: 26.39		GRWD1_HUMAN (206-342): 9.29e-18: 85.5: 17.61
+	Hs
		1202777 TCPH_HUMAN (9-538): 0: 564: 26.39		WDR5B_HUMAN (2-148): 2.99e-13: 71.4: 10.74