HitPredict

Interactor 1: TCPD (P50991)
T-complex protein 1 subunit delta (TCP-1-delta) (CCT-delta) (Chaperonin containing T-complex polypeptide 1 subunit 4) (Stimulator of TAR RNA-binding)
Gene: CCT4

Interactor 2: TCPB (P78371)
T-complex protein 1 subunit beta (TCP-1-beta) (CCT-beta) (Chaperonin containing T-complex polypeptide 1 subunit 2)
Gene: CCT2

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.95 1.00 0.976

The method score is based on:

Property Details
Experiments 32296183, 30021884, 24981860, 35271311, 37071682, 33961781, 35366418, 35235311, 34349018, 36652389, unassigned1304
Identification Methods two hybrid, proximity labelling technology, affinity chromatography technology, cross-linking study, validated two hybrid, anti tag coimmunoprecipitation, two hybrid array, two hybrid prey pooling approach
Interaction Type direct interaction, physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains Cpn60_TCP1~Cpn60_TCP1
Common GO terms GO:0002199 - zona pellucida receptor complex
GO:0005524 - ATP binding
GO:0005829 - cytosol
GO:0005832 - chaperonin-containing T-complex
GO:0005874 - microtubule
and 16 others

more...
Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 539
Hs

1 535
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+ Ph
+ Dm
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+ Ce
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+ Bt
+ Dm

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Last updated: 15 Jul 2024