HitPredict

Interactor 1: RAB7A (P51149)
Ras-related protein Rab-7a (EC 3.6.5.2)
Gene: RAB7A

Interactor 2: LTOR1 (Q6IAA8)
Ragulator complex protein LAMTOR1 (Late endosomal/lysosomal adaptor and MAPK and MTOR activator 1) (Lipid raft adaptor protein p18) (Protein associated with DRMs and endosomes) (p27Kip1-releasing factor from RhoA) (p27RF-Rho)
Gene: LAMTOR1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.71	0.60	0.656

Property	Details
Experiments	34079125, 35271311, 34432599
Identification Methods	proximity labelling technology, affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005764 - lysosome GO:0005765 - lysosomal membrane GO:0005886 - plasma membrane GO:0031902 - late endosome membrane GO:0070062 - extracellular exosome
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1 207 Hs			1 161
+	Hs
		918888 RAB1A_HUMAN (1-206): 7.27e-87: 256: 33.50		LTOR1_HUMAN (1-161): 1.93e-90: 262: 100.00
+	Hs
		1152088 RAB1B_HUMAN (1-205): 2.14e-86: 255: 34.15		LTOR1_HUMAN (1-161): 1.93e-90: 262: 100.00
+	Hs
		914141 RB11A_HUMAN (2-205): 1.09e-78: 236: 30.99		LTOR1_HUMAN (1-161): 1.93e-90: 262: 100.00
+	Hs
		845547 RAB9A_HUMAN (5-177): 3.51e-68: 209: 56.65		LTOR1_HUMAN (1-161): 1.93e-90: 262: 100.00
+	Hs
		844572 RAB5C_HUMAN (9-179): 1.56e-37: 131: 42.44		LTOR1_HUMAN (1-161): 1.93e-90: 262: 100.00