HitPredict

Interactor 1: GDF5 (P43026)
Growth/differentiation factor 5 (GDF-5) (Bone morphogenetic protein 14) (BMP-14) (Cartilage-derived morphogenetic protein 1) (CDMP-1) (Lipopolysaccharide-associated protein 4) (LAP-4) (LPS-associated protein 4) (Radotermin)
Gene: GDF5

Interactor 2: GDF5 (P43026)
Growth/differentiation factor 5 (GDF-5) (Bone morphogenetic protein 14) (BMP-14) (Cartilage-derived morphogenetic protein 1) (CDMP-1) (Lipopolysaccharide-associated protein 4) (LAP-4) (LPS-associated protein 4) (Radotermin)
Gene: GDF5

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.41 1.00 0.647

The method score is based on:

Property Details
Experiments 25174448
Identification Methods surface plasmon resonance
Interaction Type direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains TGF_beta~TGF_beta, TGF_beta~TGFb_propeptide, TGFb_propeptide~TGFb_propeptide
Common GO terms GO:0002062 - chondrocyte differentiation
GO:0005125 - cytokine activity
GO:0005576 - extracellular region
GO:0005615 - extracellular space
GO:0005886 - plasma membrane
and 21 others

more...
Homologous interactions 15

Homologous interactions

Color coding for hit scores

1 501
Hs

1 501
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Last updated: 11Aug2025