Protein: RHDF2
Inactive rhomboid protein 2 (iRhom2) (Rhomboid 5 homolog 2) (Rhomboid family member 2) (Rhomboid veinlet-like protein 5) (Rhomboid veinlet-like protein 6)

Gene: RHDF2, RHBDF2
Organism: Homo sapiens
Interactions: 165
UniProt ID: Q6PJF5

Gene Ontology (top 5):
GO:0002862 - negative regulation of inflammatory response to antigenic stimulus
GO:0005789 - endoplasmic reticulum membrane
GO:0005796 - Golgi lumen
GO:0005886 - plasma membrane
GO:0015031 - protein transport

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1079749

EREP1
Endosomal transmembrane epsin interactor 1

3

2

High-throughput

0.667

High

793113

PE2R3
Prostaglandin E2 receptor EP3 subtype

3

0

High-throughput

0.638

High

1162111

KCNS3
Potassium voltage-gated channel subfamily S member 3

2

3

High-throughput

0.628

High

1162073

RHDF2
Inactive rhomboid protein 2

1

3

High-throughput

0.618

High

622739

IL4RA
Interleukin-4 receptor subunit alpha

2

0

High-throughput

0.602

High

1067915

PDCD1
Programmed cell death protein 1

2

0

High-throughput

0.602

High

739996

TGFR2
TGF-beta receptor type-2

2

4

High-throughput

0.601

High

982154

1433F
14-3-3 protein eta

2

0

High-throughput

0.576

High

172065

GP182
G-protein coupled receptor 182

1

1

High-throughput

0.536

High

179205

COPT1
High affinity copper uptake protein 1

1

1

High-throughput

0.536

High

537751

INSRR
Insulin receptor-related protein

1

1

High-throughput

0.536

High

798152

KI2L1
Killer cell immunoglobulin-like receptor 2DL1

1

3

High-throughput

0.536

High

1086125

AMHR2
Anti-Muellerian hormone type-2 receptor

1

5

High-throughput

0.536

High

1162075

BT2A1
Butyrophilin subfamily 2 member A1

1

1

High-throughput

0.536

High

1162090

IGDC4
Immunoglobulin superfamily DCC subclass member 4

1

1

High-throughput

0.536

High

1162095

AQP3
Aquaporin-3

1

5

High-throughput

0.536

High

1162104

BSCL2
Seipin

1

1

High-throughput

0.536

High

1162110

KI2L4
Killer cell immunoglobulin-like receptor 2DL4

1

3

High-throughput

0.536

High

1162129

FLRT1
Leucine-rich repeat transmembrane protein FLRT1

1

1

High-throughput

0.536

High

1162139

CLC4A
C-type lectin domain family 4 member A

1

1

High-throughput

0.536

High

1162148

PCDB3
Protocadherin beta-3

1

2

High-throughput

0.536

High

301029

SLIK3
SLIT and NTRK-like protein 3

1

3

High-throughput

0.515

High

444746

GNAI3
Guanine nucleotide-binding protein G(i) subunit alpha-3

1

0

High-throughput

0.513

High

943979

X3CL1
Fractalkine

1

0

High-throughput

0.513

High

1016601

ASPH
Aspartyl/asparaginyl beta-hydroxylase

1

0

High-throughput

0.513

High

1053774

PIGH
Phosphatidylinositol N-acetylglucosaminyltransferase subunit H

1

0

High-throughput

0.513

High

1125026

TTMP
TPA-induced transmembrane protein

1

0

High-throughput

0.513

High

1132802

TRML2
Trem-like transcript 2 protein

1

0

High-throughput

0.513

High

1161989

TRAT1
T-cell receptor-associated transmembrane adapter 1

1

0

High-throughput

0.513

High

1162082

TCAM2
TIR domain-containing adapter molecule 2

1

0

High-throughput

0.513

High

1162094

BSND
Barttin

1

0

High-throughput

0.513

High

1162099

TR19L
Tumor necrosis factor receptor superfamily member 19L

1

0

High-throughput

0.513

High

1162107

OPALI
Opalin

1

0

High-throughput

0.513

High

1162128

GPC5B
G-protein coupled receptor family C group 5 member B

1

0

High-throughput

0.513

High

1162135

CCG4
Voltage-dependent calcium channel gamma-4 subunit

1

0

High-throughput

0.513

High

1162151

KCNE3
Potassium voltage-gated channel subfamily E member 3

1

0

High-throughput

0.513

High

1162140

CHIP
E3 ubiquitin-protein ligase CHIP

1

1

Small-scale

0.512

High

638994

S100P
Protein S100-P

1

6

High-throughput

0.489

High

661308

S10A2
Protein S100-A2

1

6

High-throughput

0.489

High

933484

TBA4A
Tubulin alpha-4A chain

1

1

High-throughput

0.489

High

1162084

NRSN1
Neurensin-1

1

1

High-throughput

0.489

High

1162102

F131C
Protein FAM131C

1

1

High-throughput

0.489

High

1162142

VSIG4
V-set and immunoglobulin domain-containing protein 4

1

2

High-throughput

0.489

High

120949

APBB1
Amyloid beta precursor protein binding family B member 1

1

1

High-throughput

0.479

High

180884

YKT6
Synaptobrevin homolog YKT6

1

3

High-throughput

0.479

High

204684

E41L2
Band 4.1-like protein 2

1

5

High-throughput

0.479

High

269004

CSDE1
Cold shock domain-containing protein E1

1

1

High-throughput

0.479

High

302724

SLIK5
SLIT and NTRK-like protein 5

1

3

High-throughput

0.479

High

307627

STBD1
Starch-binding domain-containing protein 1

1

1

High-throughput

0.479

High

310682

VAPB
Vesicle-associated membrane protein-associated protein B/C

1

6

High-throughput

0.479

High

320340

SNP29
Synaptosomal-associated protein 29

1

1

High-throughput

0.479

High

338572

EGFR
Epidermal growth factor receptor

1

2

High-throughput

0.479

High

348738

RASN
GTPase NRas

1

3

High-throughput

0.479

High

350268

RASK
GTPase KRas

1

3

High-throughput

0.479

High

403905

ITB1
Integrin beta-1

1

7

High-throughput

0.479

High

438785

SRPRA
Signal recognition particle receptor subunit alpha

1

1

High-throughput

0.479

High

514847

MPRI
Cation-independent mannose-6-phosphate receptor

1

3

High-throughput

0.479

High

820952

PRC2A
Protein PRRC2A

1

1

High-throughput

0.479

High

847514

BAP31
B-cell receptor-associated protein 31

1

1

High-throughput

0.479

High

848873

AL3A2
Aldehyde dehydrogenase family 3 member A2

1

1

High-throughput

0.479

High

856544

EFNB2
Ephrin-B2

1

2

High-throughput

0.479

High

873849

IF5
Eukaryotic translation initiation factor 5

1

1

High-throughput

0.479

High

944510

ADA17
Disintegrin and metalloproteinase domain-containing protein 17

1

1

High-throughput

0.479

High

957863

EFNB1
Ephrin-B1

1

2

High-throughput

0.479

High

973769

AKA12
A-kinase anchor protein 12

1

2

High-throughput

0.479

High

974095

DYST
Dystonin

1

4

High-throughput

0.479

High

980410

NOTC2
Neurogenic locus notch homolog protein 2

1

2

High-throughput

0.479

High

990503

CKAP4
Cytoskeleton-associated protein 4

1

1

High-throughput

0.479

High

999605

AHNK
Neuroblast differentiation-associated protein AHNAK

1

3

High-throughput

0.479

High

1027490

STX5
Syntaxin-5

1

1

High-throughput

0.479

High

1048605

DSG2
Desmoglein-2

1

2

High-throughput

0.479

High

1052230

SRC8
Src substrate cortactin

1

3

High-throughput

0.479

High

1077655

NSDHL
Sterol-4-alpha-carboxylate 3-dehydrogenase, decarboxylating

1

1

High-throughput

0.479

High

1079352

VAMP3
Vesicle-associated membrane protein 3

1

3

High-throughput

0.479

High

1138678

CDKAL
Threonylcarbamoyladenosine tRNA methylthiotransferase

1

1

High-throughput

0.479

High

1162078

LYRIC
Protein LYRIC

1

1

High-throughput

0.479

High

1162079

KTN1
Kinectin

1

3

High-throughput

0.479

High

1162081

ANKL2
Ankyrin repeat and LEM domain-containing protein 2

1

1

High-throughput

0.479

High

1162083

VRK2
Serine/threonine-protein kinase VRK2

1

1

High-throughput

0.479

High

1162085

XRN1
5'-3' exoribonuclease 1

1

1

High-throughput

0.479

High

1162087

EHBP1
EH domain-binding protein 1

1

1

High-throughput

0.479

High

1162088

VANG1
Vang-like protein 1

1

3

High-throughput

0.479

High

1162089

STT3B
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3B

1

1

High-throughput

0.479

High

1162092

CANT1
Soluble calcium-activated nucleotidase 1

1

1

High-throughput

0.479

High

1162096

UBXN4
UBX domain-containing protein 4

1

2

High-throughput

0.479

High

1162100

CCD47
PAT complex subunit CCDC47

1

1

High-throughput

0.479

High

1162101

LRC59
Leucine-rich repeat-containing protein 59

1

5

High-throughput

0.479

High

1162106

DDRGK
DDRGK domain-containing protein 1

1

1

High-throughput

0.479

High

1162108

ERBIN
Erbin

1

3

High-throughput

0.479

High

1162109

CLCC1
Chloride channel CLIC-like protein 1

1

1

High-throughput

0.479

High

1162112

COR1B
Coronin-1B

1

1

High-throughput

0.479

High

1162113

ESYT1
Extended synaptotagmin-1

1

2

High-throughput

0.479

High

1162116

LSG1
Large subunit GTPase 1 homolog

1

1

High-throughput

0.479

High

1162118

TMX1
Thioredoxin-related transmembrane protein 1

1

4

High-throughput

0.479

High

1162121

E41L5
Band 4.1-like protein 5

1

4

High-throughput

0.479

High

1162122

SEC12
Guanine nucleotide-exchange factor SEC12

1

4

High-throughput

0.479

High

1162123

GOPC
Golgi-associated PDZ and coiled-coil motif-containing protein

1

3

High-throughput

0.479

High

1162124

JPH1
Junctophilin-1

1

1

High-throughput

0.479

High

1162126

RTN4
Reticulon-4

1

3

High-throughput

0.479

High

1162131

VAPA
Vesicle-associated membrane protein-associated protein A

1

6

High-throughput

0.479

High

1162133

RRBP1
Ribosome-binding protein 1

1

3

High-throughput

0.479

High

1162134

COPG2
Coatomer subunit gamma-2

1

2

High-throughput

0.479

High

1162138

VANG2
Vang-like protein 2

1

3

High-throughput

0.479

High

1162144

E41L3
Band 4.1-like protein 3

1

4

High-throughput

0.479

High

1162146

UB2J1
Ubiquitin-conjugating enzyme E2 J1

1

1

High-throughput

0.479

High

1162149

CD2AP
CD2-associated protein

1

1

High-throughput

0.479

High

1162150

AUP1
Lipid droplet-regulating VLDL assembly factor AUP1

1

1

High-throughput

0.479

High

1162152

TX264
Testis-expressed protein 264

1

1

High-throughput

0.479

High

437392

4F2
Amino acid transporter heavy chain SLC3A2

1

0

High-throughput

0.458

High

968410

ROR2
Tyrosine-protein kinase transmembrane receptor ROR2

1

0

High-throughput

0.458

High

1071539

L2GL1
Lethal(2) giant larvae protein homolog 1

1

0

High-throughput

0.458

High

1078092

AAAT
Neutral amino acid transporter B(0)

1

0

High-throughput

0.458

High

1084053

OCLN
Occludin

1

0

High-throughput

0.458

High

1162076

GRIN1
G protein-regulated inducer of neurite outgrowth 1

1

0

High-throughput

0.458

High

1162115

ZDHC5
Palmitoyltransferase ZDHHC5

1

0

High-throughput

0.458

High

72738

B4DET5
cDNA FLJ59484, highly similar to Nuclear envelope pore membrane protein POM 121

1

1

High-throughput

0.437

High

117285

PDLI1
PDZ and LIM domain protein 1

1

4

High-throughput

0.437

High

160049

HGS
Hepatocyte growth factor-regulated tyrosine kinase substrate

1

2

High-throughput

0.437

High

170867

PGRC2
Membrane-associated progesterone receptor component 2

1

2

High-throughput

0.437

High

202651

TXNL1
Thioredoxin-like protein 1

1

3

High-throughput

0.437

High

272434

TIPRL
TIP41-like protein

1

1

High-throughput

0.437

High

277078

STAM2
Signal transducing adapter molecule 2

1

2

High-throughput

0.437

High

297506

TOX4
TOX high mobility group box family member 4

1

2

High-throughput

0.437

High

573753

PTN1
Tyrosine-protein phosphatase non-receptor type 1

1

1

High-throughput

0.437

High

727270

NU214
Nuclear pore complex protein Nup214

1

1

High-throughput

0.437

High

785970

LAP2B
Lamina-associated polypeptide 2, isoforms beta/gamma

1

1

High-throughput

0.437

High

801204

KI67
Proliferation marker protein Ki-67

1

3

High-throughput

0.437

High

834617

NU153
Nuclear pore complex protein Nup153

1

6

High-throughput

0.437

High

834773

RBP2
E3 SUMO-protein ligase RanBP2

1

2

High-throughput

0.437

High

838915

EMD
Emerin

1

1

High-throughput

0.437

High

949493

RL24
Large ribosomal subunit protein eL24

1

1

High-throughput

0.437

High

1059235

GOGB1
Golgin subfamily B member 1

1

2

High-throughput

0.437

High

1127964

TOIP1
Torsin-1A-interacting protein 1

1

1

High-throughput

0.437

High

1162074

LARP1
La-related protein 1

1

1

High-throughput

0.437

High

1162077

ZCCHV
Zinc finger CCCH-type antiviral protein 1

1

1

High-throughput

0.437

High

1162086

MACOI
Macoilin

1

1

High-throughput

0.437

High

1162097

STAM1
Signal transducing adapter molecule 1

1

2

High-throughput

0.437

High

1162103

EFHD2
EF-hand domain-containing protein D2

1

2

High-throughput

0.437

High

1162105

PDLI5
PDZ and LIM domain protein 5

1

3

High-throughput

0.437

High

1162117

SLK
STE20-like serine/threonine-protein kinase

1

1

High-throughput

0.437

High

1162119

GCP60
Golgi resident protein GCP60

1

1

High-throughput

0.437

High

1162120

PKHA5
Pleckstrin homology domain-containing family A member 5

1

4

High-throughput

0.437

High

1162127

WWOX
WW domain-containing oxidoreductase

1

1

High-throughput

0.437

High

1162130

RAI14
Ankycorbin

1

3

High-throughput

0.437

High

1162136

ZRAN1
Ubiquitin thioesterase ZRANB1

1

5

High-throughput

0.437

High

1162141

SCML2
Sex comb on midleg-like protein 2

1

1

High-throughput

0.437

High

1162143

FND3A
Fibronectin type-III domain-containing protein 3A

1

3

High-throughput

0.437

High

1162145

MAN1
Inner nuclear membrane protein Man1

1

1

High-throughput

0.437

High

1117361

TM52B
Transmembrane protein 52B

2

0

High-throughput

0.318

High

896467

UBE2N
Ubiquitin-conjugating enzyme E2 N

2

0

Small-scale

0.305

High

1162114

TRI31
E3 ubiquitin-protein ligase TRIM31

1

0

Small-scale

0.301

High

1162098

UBP13
Ubiquitin carboxyl-terminal hydrolase 13

1

0

Small-scale

0.292

High

237814

TSN3
Tetraspanin-3

1

0

High-throughput

0.279

Low

885930

EVA1C
Protein eva-1 homolog C

1

0

High-throughput

0.279

Low

1139953

SPRY7
SPRY domain-containing protein 7

1

0

High-throughput

0.279

Low

1162080

T200A
Transmembrane protein 200A

1

0

High-throughput

0.279

Low

1162091

CC107
Coiled-coil domain-containing protein 107

1

0

High-throughput

0.279

Low

1162093

KCNE4
Potassium voltage-gated channel subfamily E member 4

1

0

High-throughput

0.279

Low

1162125

TMM9B
Transmembrane protein 9B

1

0

High-throughput

0.279

Low

1162137

HSPB8
Heat shock protein beta-8

1

0

High-throughput

0.279

Low

312300

IPO7
Importin-7

1

0

High-throughput

0.249

Low

1033115

UB2V1
Ubiquitin-conjugating enzyme E2 variant 1

1

0

Small-scale

0.249

Low

1162132

F135A
Protein FAM135A

1

0

High-throughput

0.249

Low

1162147

UBP15
Ubiquitin carboxyl-terminal hydrolase 15

1

0

Small-scale

0.249

Low


Service provided by Combinatics, Japan

Last updated: 15 Jul 2024