Interactor 1: BRCA2 (P51587)
Breast cancer type 2 susceptibility protein (Fanconi anemia group D1 protein)
Gene: BRCA2

Interactor 2: BARD1 (Q99728)
BRCA1-associated RING domain protein 1 (BARD-1) (EC 2.3.2.27) (RING-type E3 ubiquitin transferase BARD1)
Gene: BARD1

Species: Homo sapiens

Source: innatedb

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.80 0.55 0.667

The method score is based on:

Property Details
Experiments 14636569, 19176389, 17664283, 16391231
Identification Methods pull down, biochemical, affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type direct interaction, association, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0000152 - nuclear ubiquitin ligase complex
GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0071479 - cellular response to ionizing radiation
GO:2000001 - regulation of DNA damage checkpoint
Homologous interactions 0

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024