HitPredict

Interactor 1: VAMP7 (P51809)
Vesicle-associated membrane protein 7 (VAMP-7) (Synaptobrevin-like protein 1) (Tetanus-insensitive VAMP) (Ti-VAMP)
Gene: VAMP7

Interactor 2: RHOB (P62745)
Rho-related GTP-binding protein RhoB (Rho cDNA clone 6) (h6)
Gene: RHOB

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	34079125, 31871319
Identification Methods	proximity labelling technology, affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane GO:0008333 - endosome to lysosome transport GO:0031902 - late endosome membrane GO:0070062 - extracellular exosome
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 220 Hs			1 196
+	Hs
		850556 VAMP7_HUMAN (1-220): 3.87e-90: 266: 100.00		RAC1_HUMAN (1-196): 2.37e-79: 236: 55.10
+	Hs
		850552 VAMP7_HUMAN (1-220): 3.87e-90: 266: 100.00		RHOA_HUMAN (1-196): 7.19e-78: 232: 83.67
+	Hs
		545275 VAMP7_HUMAN (1-220): 3.87e-90: 266: 100.00		RAC2_HUMAN (1-196): 7.63e-77: 230: 53.57
+	Hs
		436215 VAMP7_HUMAN (1-220): 3.87e-90: 266: 100.00		RHOC_HUMAN (1-196): 8.84e-76: 227: 83.16
+	Hs
		850558 VAMP7_HUMAN (1-220): 3.87e-90: 266: 100.00		RHOG_HUMAN (1-196): 8.84e-76: 227: 51.53
+	Hs
		850548 VAMP7_HUMAN (1-220): 3.87e-90: 266: 100.00		RAC3_HUMAN (1-179): 1.15e-74: 224: 57.54
+	Hs
		850550 VAMP7_HUMAN (1-220): 3.87e-90: 266: 100.00		CDC42_HUMAN (1-196): 1.35e-74: 224: 49.49
+	Hs
		564456 VAMP7_HUMAN (1-220): 3.87e-90: 266: 100.00		RHOQ_HUMAN (2-195): 6.71e-68: 207: 51.74
+	Hs
		120358 VAMP7_HUMAN (1-220): 3.87e-90: 266: 100.00		RHOD_HUMAN (7-182): 3.37e-66: 203: 53.98
+	Hs
		263218 SC22B_HUMAN (23-206): 4.4e-59: 186: 22.16		RAC1_HUMAN (1-196): 2.37e-79: 236: 55.10
+	Hs
		263212 SC22B_HUMAN (23-206): 4.4e-59: 186: 22.16		RHOA_HUMAN (1-196): 7.19e-78: 232: 83.67
+	Hs
		263216 SC22B_HUMAN (23-206): 4.4e-59: 186: 22.16		RHOB_HUMAN (1-196): 7.52e-78: 232: 100.00
+	Hs
		263159 SC22B_HUMAN (23-206): 4.4e-59: 186: 22.16		RAC2_HUMAN (1-196): 7.63e-77: 230: 53.57
+	Hs
		263146 SC22B_HUMAN (23-206): 4.4e-59: 186: 22.16		RHOC_HUMAN (1-196): 8.84e-76: 227: 83.16
+	Hs
		263221 SC22B_HUMAN (23-206): 4.4e-59: 186: 22.16		RHOG_HUMAN (1-196): 8.84e-76: 227: 51.53
+	Hs
		263209 SC22B_HUMAN (23-206): 4.4e-59: 186: 22.16		RAC3_HUMAN (1-179): 1.15e-74: 224: 57.54
+	Hs
		263210 SC22B_HUMAN (23-206): 4.4e-59: 186: 22.16		CDC42_HUMAN (1-196): 1.35e-74: 224: 49.49
+	Hs
		180793 YKT6_HUMAN (23-179): 3.99e-55: 176: 23.42		RHOC_HUMAN (1-196): 8.84e-76: 227: 83.16
+	Hs
		120240 SC22B_HUMAN (23-206): 4.4e-59: 186: 22.16		RHOD_HUMAN (7-182): 3.37e-66: 203: 53.98
+	Hs
		120218 YKT6_HUMAN (23-179): 3.99e-55: 176: 23.42		RHOD_HUMAN (7-182): 3.37e-66: 203: 53.98