HitPredict

Interactor 1: HDGF (P51858)
Hepatoma-derived growth factor (HDGF) (High mobility group protein 1-like 2) (HMG-1L2)
Gene: HDGF

Interactor 2: H31 (P68431)
Histone H3.1 (Histone H3/a) (Histone H3/b) (Histone H3/c) (Histone H3/d) (Histone H3/f) (Histone H3/h) (Histone H3/i) (Histone H3/j) (Histone H3/k) (Histone H3/l)
Gene: H3C1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.83	1.00	0.915

Property	Details
Experiments	25281560, 29568061, 36089195, 34349018, 21907836
Identification Methods	proximity labelling technology, cross-linking study, affinity chromatography technology, tandem affinity purification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	Histone~PWWP
Common GO terms	GO:0005576 - extracellular region GO:0005634 - nucleus GO:0005654 - nucleoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 240 Hs			1 136
+	Hs
		850901 HDGF_HUMAN (1-240): 4.63e-53: 173: 100.00		H33_HUMAN (1-136): 2.73e-61: 186: 96.32
+	Hs
		855452 MSH6_HUMAN (5-232): 3.82e-46: 165: 18.55		H31_HUMAN (1-136): 2.8e-62: 188: 100.00
+	Hs
		855454 MSH6_HUMAN (5-232): 3.82e-46: 165: 18.55		H33_HUMAN (1-136): 2.73e-61: 186: 96.32
+	Hs
		934827 GLYR1_HUMAN (6-228): 2.27e-46: 163: 25.94		H31_HUMAN (1-136): 2.8e-62: 188: 100.00
+	Hs
		1086171 GLYR1_HUMAN (6-228): 2.27e-46: 163: 25.94		H31T_HUMAN (1-136): 1.27e-61: 187: 97.06
+	Hs
		952374 GLYR1_HUMAN (6-228): 2.27e-46: 163: 25.94		H33_HUMAN (1-136): 2.73e-61: 186: 96.32
+	Hs
		111558 MSH6_HUMAN (5-232): 3.82e-46: 165: 18.55		K7EK07_HUMAN (1-132): 2.4e-59: 181: 96.21
+	Hs
		935364 ZMYD8_HUMAN (3-233): 1.74e-41: 152: 20.59		H31_HUMAN (1-136): 2.8e-62: 188: 100.00
+	Hs
		265990 PSIP1_HUMAN (7-239): 7.38e-38: 140: 37.60		H31_HUMAN (1-136): 2.8e-62: 188: 100.00
+	Hs
		935205 NSD3_HUMAN (8-222): 4.17e-37: 140: 16.74		H31_HUMAN (1-136): 2.8e-62: 188: 100.00
+	Hs
		1086307 NSD3_HUMAN (8-222): 4.17e-37: 140: 16.74		H31T_HUMAN (1-136): 1.27e-61: 187: 97.06
+	Hs
		265993 PSIP1_HUMAN (7-239): 7.38e-38: 140: 37.60		H33_HUMAN (1-136): 2.73e-61: 186: 96.32
+	Hs
		952607 NSD3_HUMAN (8-222): 4.17e-37: 140: 16.74		H33_HUMAN (1-136): 2.73e-61: 186: 96.32
+	Hs
		331780 NSD2_HUMAN (9-226): 4.97e-34: 131: 19.18		H31_HUMAN (1-136): 2.8e-62: 188: 100.00
+	Hs
		1157224 NSD3_HUMAN (8-222): 4.17e-37: 140: 16.74		H3C_HUMAN (1-136): 5.49e-58: 177: 93.38
+	Hs
		828177 MSH6_HUMAN (5-232): 3.82e-46: 165: 18.55		CENPA_HUMAN (9-133): 5.62e-45: 145: 50.00
+	Hs
		828247 GLYR1_HUMAN (6-228): 2.27e-46: 163: 25.94		CENPA_HUMAN (9-133): 5.62e-45: 145: 50.00
+	Hs
		265969 PSIP1_HUMAN (7-239): 7.38e-38: 140: 37.60		CENPA_HUMAN (9-133): 5.62e-45: 145: 50.00
+	Hs
		828367 NSD3_HUMAN (8-222): 4.17e-37: 140: 16.74		CENPA_HUMAN (9-133): 5.62e-45: 145: 50.00
+	Hs
		331748 NSD2_HUMAN (9-226): 4.97e-34: 131: 19.18		CENPA_HUMAN (9-133): 5.62e-45: 145: 50.00