Protein: VSTM1
V-set and transmembrane domain-containing protein 1 (Signal inhibitory receptor on leukocytes-1) (SIRL-1)

Gene: VSTM1
Organism: Homo sapiens
Interactions: 55
UniProt ID: Q6UX27

Gene Ontology (top 5):
GO:0002376 - immune system process
GO:0002764 - immune response-regulating signaling pathway
GO:0005125 - cytokine activity
GO:0005615 - extracellular space
GO:0005886 - plasma membrane

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

553358

FCGR1
High affinity immunoglobulin gamma Fc receptor I

2

8

High-throughput

0.783

High

1249511

LRC4C
Leucine-rich repeat-containing protein 4C

2

0

High-throughput

0.742

High

224444

PLPP2
Phospholipid phosphatase 2

2

1

High-throughput

0.606

High

337887

CLD7
Claudin-7

2

2

High-throughput

0.606

High

338257

CLD9
Claudin-9

2

2

High-throughput

0.606

High

622066

CD53
Leukocyte surface antigen CD53

2

3

High-throughput

0.606

High

1249493

AGRG3
Adhesion G protein-coupled receptor G3

2

2

High-throughput

0.606

High

1249494

CLC10
C-type lectin domain family 10 member A

2

2

High-throughput

0.606

High

540515

LAMP1
Lysosome-associated membrane glycoprotein 1

2

0

High-throughput

0.580

High

870050

KCNJ6
G protein-activated inward rectifier potassium channel 2

2

0

High-throughput

0.580

High

1249496

GOLM1
Golgi membrane protein 1

2

0

High-throughput

0.580

High

1249502

APH1B
Gamma-secretase subunit APH-1B

2

0

High-throughput

0.580

High

1249517

HCST
Hematopoietic cell signal transducer

2

0

High-throughput

0.580

High

275046

COQ9
Ubiquinone biosynthesis protein COQ9, mitochondrial

2

1

High-throughput

0.553

High

335250

CXB5
Gap junction beta-5 protein

2

1

High-throughput

0.553

High

1249501

GPX8
Probable glutathione peroxidase 8

2

1

High-throughput

0.553

High

609714

LEG3
Galectin-3

1

1

High-throughput

0.536

High

722497

CTR1
High affinity cationic amino acid transporter 1

1

1

High-throughput

0.536

High

1249498

STEA2
Metalloreductase STEAP2

1

1

High-throughput

0.536

High

1249503

CTR3
Cationic amino acid transporter 3

1

1

High-throughput

0.536

High

1144969

RAB35
Ras-related protein Rab-35

1

0

High-throughput

0.513

High

1249505

MAGT1
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit MAGT1

1

0

High-throughput

0.513

High

1249516

S53A1
Solute carrier family 53 member 1

1

0

High-throughput

0.513

High

231492

ORC4
Origin recognition complex subunit 4

1

1

High-throughput

0.489

High

248596

FADS1
Acyl-CoA

1

1

High-throughput

0.489

High

269021

ABCB7
Iron-sulfur clusters transporter ABCB7, mitochondrial

1

1

High-throughput

0.489

High

1200259

FAKD1
FAST kinase domain-containing protein 1, mitochondrial

1

3

High-throughput

0.489

High

1249492

CERS6
Ceramide synthase 6

1

1

High-throughput

0.489

High

1249499

GOGA5
Golgin subfamily A member 5

1

1

High-throughput

0.489

High

1249510

XPO5
Exportin-5

1

5

High-throughput

0.489

High

1249512

AT131
Endoplasmic reticulum transmembrane helix translocase

1

3

High-throughput

0.489

High

1249518

XPO7
Exportin-7

1

6

High-throughput

0.489

High

1249520

KDIS
Kinase D-interacting substrate of 220 kDa

1

3

High-throughput

0.489

High

1249522

TNPO3
Transportin-3

1

6

High-throughput

0.489

High

385869

LMNA
Prelamin-A/C [Cleaved into: Lamin-A/C

1

1

High-throughput

0.439

High

1207524

F209A
Protein FAM209A

1

1

High-throughput

0.439

High

1108931

AQP6
Aquaporin-6

2

0

High-throughput

0.316

High

1187471

AR13B
ADP-ribosylation factor-like protein 13B

2

0

High-throughput

0.316

High

1216320

MFS4B
Sodium-dependent glucose transporter 1

2

0

High-throughput

0.316

High

1234423

MRM1
rRNA methyltransferase 1, mitochondrial

2

0

High-throughput

0.316

High

1249500

FNDC9
Fibronectin type III domain-containing protein 9

2

0

High-throughput

0.316

High

1249504

FATE1
Fetal and adult testis-expressed transcript protein

2

0

High-throughput

0.316

High

1249506

STMN4
Stathmin-4

2

0

High-throughput

0.316

High

1249509

MANS1
MANSC domain-containing protein 1

2

0

High-throughput

0.316

High

1249515

TM248
Transmembrane protein 248

2

0

High-throughput

0.316

High

1249519

FBX2
F-box only protein 2

2

0

High-throughput

0.316

High

1249521

ERGI3
Endoplasmic reticulum-Golgi intermediate compartment protein 3

2

0

High-throughput

0.316

High

162102

ACOT8
Acyl-coenzyme A thioesterase 8

1

0

High-throughput

0.279

Low

1180368

HKDC1
Hexokinase HKDC1

1

0

High-throughput

0.279

Low

1249495

EMC1
ER membrane protein complex subunit 1

1

0

High-throughput

0.279

Low

1249497

MROH1
Maestro heat-like repeat-containing protein family member 1

1

0

High-throughput

0.279

Low

1249507

HEAT1
HEAT repeat-containing protein 1

1

0

High-throughput

0.279

Low

1249508

OPA3
Optic atrophy 3 protein

1

0

High-throughput

0.279

Low

1249513

ZDH18
Palmitoyltransferase ZDHHC18

1

0

High-throughput

0.279

Low

1249514

INT7
Integrator complex subunit 7

1

0

High-throughput

0.279

Low


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Last updated: 11Aug2025